Insider List

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Total 56

Insider Name
Aaron Schuchart
Ag Novartis
Alison Frances Lawton
Anthony G. Quinn
Armen Shanafelt
Baker Bros. Advisors (gp) Llc
Baker Bros. Advisors Lp
Baker Brothers Life Sciences Lp
Cameron Turtle
David George Lowe
Fairmount Funds Management Llc
Fairmount Healthcare Co-invest L.p.
Fairmount Healthcare Fund Ii L.p.
Fairmount Healthcare Fund L.p.
Felix Baker
George Georgiou
Hanley Jr. Michael Conick
Heidy King-jones
Henry Hebel
Hunter C Smith
Ivana Magovcevic-liebisch
James Paul Kastenmayer
James Wooldridge
Jeff Marc Goldberg
Jeffrey W. Albers
Jonathan Alspaugh
Joseph E Tyler
Julian Baker
L.p. 667,
Laurie Stelzer
Leslie Sloan
Lilly Eli & Co
Lilly Ventures Fund I Llc
Linda L Neuman
Madduri Ravin Rao
Marcio Souza
Michael Thomas Henderson
Novartis Bioventures Ltd
Orbimed Advisors Llc
Orbimed Capital Gp V Llc

Insider Name	Latest Transaction Date	Aggregate Performance						Aggregate Performance Relative to S&P 500						Companys
Insider Name	Latest Transaction Date	1M	3M	6M	1Y	2Y	3Y	1M	3M	6M	1Y	2Y	3Y	Companys
Insider Name	Latest Transaction Date	Aggregate Performance						Aggregate Performance Relative to S&P 500						Companys
Insider Name	Latest Transaction Date	1M	3M	6M	1Y	2Y	3Y	1M	3M	6M	1Y	2Y	3Y	Companys
Aaron Schuchart	2018-09-27	-	-	-	-	-	-	-	-	-	-	-	-	SYRE LUMO
Ag Novartis	2010-04-23	7.570	7.570	-15.260	-27.840	-23.570	-3.310	11.780	6.280	-22.000	-44.120	-36.910	-14.930	CBMG PSTX AKUS FMTX GRTX BCYC ... ARPO RNTX NTLA ALT AVXS SYRE SURF FIXX RARX PTI ELDN ALNY ATRX MNTA WHWK YMTX DTIL KANT QTTB
Alison Frances Lawton		-	-	-	-	-	-	-	-	-	-	-	-	XFOR KLDO VSTM CLCD MLND TPST ... SYRE MGTA DNTH
Anthony G. Quinn	2025-01-13	-0.540	-0.540	6.520	-7.530	-6.470	-25.660	-3.300	-0.780	3.680	-13.050	-19.140	-37.040	KLDO GBIO SYRE
Armen Shanafelt	2021-12-13	13.800	13.800	-25.630	-52.040	-49.500	-28.270	13.250	21.730	-26.500	-57.480	-56.460	-39.210	SURF SYRE RNTX PTGX
Baker Bros. Advisors (gp) Llc	2015-08-07	-	-	-	-	-	-	-	-	-	-	-	-	TCRX NGNE MDGL BCYC IGMS NTLA ... RYTM XOMA INCY BCRX ONC ACAD KOD KALA SERA CELC DBVT SYRE VTVT IMCR PRLD TRDA DNLI KNSA REPL HOOK KYMR
Baker Bros. Advisors Lp	2025-09-08	3.320	3.320	11.670	26.470	-9.270	-16.960	1.750	10.020	4.270	11.670	-21.510	-28.370	IGMS INCY KOD PRLD KNSA BCEL ... ONC ACAD SGEN ALXN ZYME NLTX ACGN HOOK PRNB NVTAQ BLCM MRTX RYTM BCRX NTLA XOMA XOMAO.PFD TLIS DBVT SYRE TRDA TCRX MDGL NGNE BCYC KALA SERA CELC VTVT IMCR DNLI REPL KYMR
Baker Brothers Life Sciences Lp	2013-01-18	-	-	-	-	-	-	-	-	-	-	-	-	IGMS INCY KOD PRLD KNSA ONC ... ACAD SGEN ALXN ZYME NLTX ACGN XOMA MRTX BCRX XOMAO.PFD TLIS DBVT SYRE TCRX MDGL NGNE BCYC VTVT IMCR DNLI REPL KYMR
Cameron Turtle	2020-12-28	-	-	-	-	-	-	-	-	-	-	-	-	BBIO EIDX SYRE ORKA
David George Lowe	2009-01-27	-	-	-	-	-	-	-	-	-	-	-	-	SYRE ABIO ORKA
Fairmount Funds Management Llc	2025-07-10	3.960	3.960	79.690	74.730	37.140	-1.340	4.070	3.210	66.470	48.070	15.460	-19.380	COGT VRDN SYRE APGE MGTA ZBIO ... ORKA CBIO DNTH JBIO
Fairmount Healthcare Co-invest L.p.		-	-	-	-	-	-	-	-	-	-	-	-	SYRE
Fairmount Healthcare Fund Ii L.p.	2025-10-07	22.360	22.360	-54.090	1.500	-	-	19.260	-59.030	-54.190	-15.780	-	-	VRDN SYRE APGE ZBIO ORKA CBIO ... JBIO
Fairmount Healthcare Fund L.p.	2023-07-13	-	-	-	-	-	-	-	-	-	-	-	-	VRDN SYRE APGE
Felix Baker	2016-11-08	5.580	5.580	22.870	29.840	19.200	11.310	4.360	7.520	14.590	14.110	4.670	0.940	IGMS INCY KOD PRLD KNSA BCEL ... ONC ACAD SGEN ALXN ZYME NLTX ACGN HOOK PRNB NVTAQ BLCM MRTX RYTM BCRX NTLA XOMA OCRX HRTX XOMAO.PFD TLIS DBVT SYRE TRDA TCRX MDGL NGNE BCYC KALA SERA CELC VTVT IMCR DNLI REPL KYMR
George Georgiou		-	-	-	-	-	-	-	-	-	-	-	-	SYRE
Hanley Jr. Michael Conick	2022-06-08	-25.330	-25.330	-45.800	-81.520	38.670	-1.040	-20.070	-25.950	-42.100	-85.850	24.690	-14.440	SYRE ANRO
Heidy King-jones		-	-	-	-	-	-	-	-	-	-	-	-	PRVB AXLA SYRE
Henry Hebel		-	-	-	-	-	-	-	-	-	-	-	-	SYRE
Hunter C Smith	2025-08-13	-	-	-	-	-	-	-	-	-	-	-	-	RYTM GWR SYRE
Ivana Magovcevic-liebisch	2024-12-19	1.940	1.940	175.570	17.060	13.330	13.770	0.140	18.920	173.510	2.450	1.880	1.380	SYRE AGTC DYAX ABSI VIGL QTRX ... ACRV
James Paul Kastenmayer		-	-	-	-	-	-	-	-	-	-	-	-	VIE SYRE AVBP
James Wooldridge		-	-	-	-	-	-	-	-	-	-	-	-	CMPI SYRE
Jeff Marc Goldberg	2019-04-08	-	-	-	-	-	-	-	-	-	-	-	-	AKCA SYRE
Jeffrey W. Albers	2025-10-13	-	-	-	-	-	-	-	-	-	-	-	-	BPMC KYMR MGTA SYRE DNTH
Jonathan Alspaugh	2022-03-11	16.460	16.460	-70.310	-87.710	-45.360	-35.990	14.500	-31.790	-64.190	-78.880	-48.460	-44.970	SYRE
Joseph E Tyler		-	-	-	-	-	-	-	-	-	-	-	-	SYRE MNTA
Julian Baker	2016-10-07	1.250	1.250	-1.670	38.110	-4.720	-4.650	-1.020	-1.590	-8.780	17.980	-22.120	-18.490	IGMS INCY KOD PRLD KNSA BCEL ... ONC ACAD SGEN ALXN ZYME NLTX ACGN HOOK PRNB NVTAQ BLCM MRTX RYTM BCRX NTLA XOMA OCRX HRTX INVA XOMAO.PFD TLIS DBVT SYRE TRDA TCRX MDGL NGNE BCYC KALA SERA CELC VTVT IMCR DNLI REPL KYMR
L.p. 667,	2013-01-18	-	-	-	-	-	-	-	-	-	-	-	-	IGMS INCY KOD PRLD KNSA ONC ... ACAD SGEN ALXN ZYME NLTX ACGN XOMA MRTX BCRX XOMAO.PFD TLIS DBVT SYRE TCRX MDGL NGNE BCYC VTVT IMCR DNLI REPL KYMR
Laurie Stelzer	2015-08-20	11.580	11.580	-51.690	-41.910	-16.860	-0.250	15.400	-1.170	-45.900	-49.190	-26.030	-12.200	PMVP SURF ARNA HALO MRTX SYRE ... SION
Leslie Sloan		-	-	-	-	-	-	-	-	-	-	-	-	SYRE
Lilly Eli & Co	2023-08-11	-5.760	-5.760	-48.220	-57.600	-43.090	-9.090	-7.470	-42.980	-57.190	-77.960	-51.660	-21.230	RNA DERM ELAN ZYME LPTX CLCD ... SYRE ZSANQ CHRS DARE UTHR IONS SGTX AKUS
Lilly Ventures Fund I Llc	2018-04-23	13.530	13.530	-7.370	-39.500	-46.620	-25.530	12.730	41.390	-15.100	-51.390	-55.770	-37.110	SURF RNTX PTGX SYRE CHRS DARE
Linda L Neuman		-	-	-	-	-	-	-	-	-	-	-	-	SYRE
Madduri Ravin Rao		-	-	-	-	-	-	-	-	-	-	-	-	SYRE DBVT
Marcio Souza	2023-06-27	25.260	25.260	12.180	64.380	8.940	-20.130	26.060	64.460	7.780	46.290	-3.340	-31.220	PRAX PTCT CLPT SYRE
Michael Thomas Henderson	2019-07-01	8.480	8.480	28.060	10.820	52.360	-28.680	8.840	-22.830	19.070	5.720	31.670	-37.540	BBIO ADGM SYRE APGE
Novartis Bioventures Ltd	2020-06-30	-1.780	-1.780	30.640	12.760	-22.720	-10.070	-5.070	2.900	20.950	-5.870	-38.800	-21.650	AKUS FMTX GRTX BCYC ARPO RNTX ... ALT SYRE RARX PTI ELDN AKBA EIGRQ ATRX WHWK YMTX KANT
Orbimed Advisors Llc	2025-10-08	4.000	4.000	1.110	-1.730	-8.760	-13.550	3.480	5.010	-3.840	-13.220	-19.930	-24.890	ARQT XTNT LOGC CALC PRLD PMVP ... ETNB INSP AFIB PAND FUSN RPTX SCPH ORIC ALEC KROS IMRA CTIC PASG SRRA TCDAQ TELA SWTX CRVS PRVL PRNB NXTC TPTX AVDR ALPN THOR SIBN GH ARVN STDY VRAYQ CNST CRNX ARPO ARMO ADAPY RYTM PIRS BOLD GKOS KALA SYBX LOXO XFOR ROKA SYRE NBRVF RPBIF RLYP RNAC NTLA OTIC DMTX SIENQ ICPT MRTX XLRN SUPN ANTH AMRN PCRX CCXI ATHXQ NXTM KURU ALBO ARYX PODD WHWK NPCE DBTX VRNA SBTX EWTX ACET CMPX THRX KNTE GLTO IRON JANX TERN IKNA THRD SPRY ELVN TSBX PVLA MBX TRAW QTTB AVBP UPB SION STTK IMA
Orbimed Capital Gp V Llc		-	-	-	-	-	-	-	-	-	-	-	-	PMVP INSP TCDAQ CRVS SIBN ARPO ... ARMO ADAPY RYTM LOXO SYRE NBRVF NTLA DMTX WHWK ACET CMPX

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Total 56

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