Denali Therapeutics Inc

NEW
NAS:DNLI (USA)  
$ 22.28 -0.51 (-2.24%) 10:08 PM EST
At Loss
P/B:
4.26
Market Cap:
$ 3.56B
Enterprise V:
$ 2.88B
Volume:
799.46K
Avg Vol (2M):
1.45M
Trade In:
Volume:
799.46K
At Loss
Avg Vol (2M):
1.45M

Business Description

Denali Therapeutics Inc
NAICS : 325414 SIC : 2836
ISIN : US24823R1059

Total Employee Number:

507
Description
Denali Therapeutics Inc is a biotechnology company that is engaged in developing and discovering therapeutics to defeat neurodegenerative diseases. The company's development programs include the LRRK2 Inhibitor Program, which develops brain penetrant small molecule LRRK2 inhibitor product candidates for Parkinson's disease. Its key products include DNL201, DNL151, ATV (Antibody Transport Vehicle), ETV (Enzyme Transport Vehicle), and others. The Company has one operating segment with the goal to discover, develop, and commercializing therapeutics.
Name Current Vs Industry Vs History
Cash-To-Debt
22.06
Equity-to-Asset
0.72
Debt-to-Equity
0.04
Debt-to-EBITDA
-0.06
Interest Coverage
N/A
N/A
N/A
Piotroski F-Score
3/9
0
1
2
3
4
5
6
7
8
9
Altman Z-Score
3.06
Distress
Grey
Safe
WACC vs ROIC
WACC
ROIC
Name Current Vs Industry Vs History
5-Day RSI
14.1
9-Day RSI
27.05
14-Day RSI
35.4
3-1 Month Momentum %
20.01
6-1 Month Momentum %
18.65
12-1 Month Momentum %
63.42

Liquidity Ratio

Name Current Vs Industry Vs History
Current Ratio
8.37
Quick Ratio
8.32
Cash Ratio
7.89
Days Inventory
16244.46
Days Sales Outstanding
309.1
Days Payable
57384.28

Dividend & Buy Back

Name Current Vs Industry Vs History
3-Year Average Share Buyback Ratio
-4.7
Shareholder Yield %
0.34
Name Current Vs Industry Vs History
Gross Margin %
97.42
Operating Margin %
-15058.19
Net Margin %
-14191.2
EBITDA Margin %
-14617.31
FCF Margin %
-12937.21
OCF Margin %
-12043.29
ROE %
-54.08
ROA %
-44.16
ROIC %
-177.64
3-Year ROIIC %
225.04
ROC (Joel Greenblatt) %
-449.3
ROCE %
-51.09
Years of Profitability over Past 10-Year
1
Moat Score
6
Tariff Resilience Score
7

Financials (Next Earnings Date:2026-11-06 Est.)

DNLI's 30-Y Financials
Income Statement Breakdown FY
Not Enough Data
Balance Sheet Breakdown
Not Enough Data
Cashflow Statement Breakdown
Not Enough Data

Operating Revenue by Business Segment

Operating Revenue by Geographic Region

Historical Operating Revenue by Business Segment

Historical Operating Revenue by Geographic Region

5-Step DuPont Analysis as of
Not Enough Data

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Performance

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Log
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Annualized Return %  

Symbol
1 Week
1 Month
3 Months
6 Months
YTD
1 Year
3 Years
5 Years
10 Years

Total Annual Return %  

Symbol
2026
2025
2024
2023
2022
2021
2020
2019
2018
2017

Denali Therapeutics Inc Executives

Details

GF Valueâ„¢

Valuation Chart

Year:

Analyst Estimate

Key Statistics

Name Value
Revenue (TTM) (Mil $) 3.604
EPS (TTM) ($) -2.84
Beta 1.4051
3-Year Sharpe Ratio 0.22
3-Year Sortino Ratio 0.33
Volatility % 51.12
14-Day RSI 35.4
14-Day ATR ($) 0.908482
20-Day SMA ($) 24.28625
12-1 Month Momentum % 63.42
52-Week Range ($) 12.58 - 27.3
Shares Outstanding (Mil) 159.85

Piotroski F-Score Details

Year:
Component Result
Piotroski F-Score 3
Positive ROA
Positive CFROA
Higher ROA yoy
CFROA > ROA
Lower Leverage yoy
Higher Current Ratio yoy
Less Shares Outstanding yoy
Higher Gross Margin yoy
Higher Asset Turnover yoy

Denali Therapeutics Inc Filings

Filing Date Document Date Form
No Filing Data

Denali Therapeutics Inc Stock Events

Financials Calendars
Event Date Price ($)
Annual report for 2026 2027-02-26 In 173 days
Fourth quarter earnings results for 2026 2027-02-26 In 173 days
Third quarter earnings results for 2026 2026-11-06 In 61 days
Second quarter earnings conference call for 2026 2026-08-06 16:30 24.42 (+0.54%)
Second quarter earnings results for 2026 2026-08-06 24.42 (+0.54%)
General meeting for 2026 2026-06-03 10:00 19.35 (-3.06%)
First quarter earnings results for 2026 2026-05-07 20.41 (+6.19%)
Annual report for 2025 2026-02-26 22.29 (+3.19%)
Fourth quarter earnings results for 2025 2026-02-26 22.29 (+3.19%)
Guidance call for 2026 2026-02-05 12:30 21.28 (-3.18%)
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Denali Therapeutics Inc Frequently Asked Questions

What is Denali Therapeutics Inc(DNLI)'s stock price today?
The current price of DNLI is $22.28. The 52 week high of DNLI is $27.30 and 52 week low is $12.58.
When is next earnings date of Denali Therapeutics Inc(DNLI)?
The next earnings date of Denali Therapeutics Inc(DNLI) is 2026-11-06 Est..
Does Denali Therapeutics Inc(DNLI) pay dividends? If so, how much?
Denali Therapeutics Inc(DNLI) does not pay dividend.

Guru Commentaries on NAS:DNLI

2026 Q2
ACATIS Investment report July 2026
What the manager wrote

Denali Therapeutics is a promising investment due to its innovative transport vehicle platform, which is essential for delivering enzymes or antibodies across the blood-brain barrier. This technology is crucial for treating conditions like Alzheimer's and Parkinson's disease. The company has already achieved a significant milestone with the approval of a medication for Hunter Syndrome. The market has overlooked Denali, despite its potential to address major health challenges associated with an aging population.

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