Insider List

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Total 47

Insider Name
Alexander A Fitzpatrick
Alexandria Venture Investments, Llc
Brent L Saunders
Brian Dorsey
Casey M Tansey
Deerfield Management Company, L.p. (series C)
Deerfield Mgmt Iii, L.p.
Deerfield Mgmt Iv, L.p.
Deerfield Private Design Fund Iii, L.p.
Deerfield Private Design Fund Iv, L.p.
Eric Karas
James E Flynn
Jeffrey C. Pepe
Jonathan D Root
Jonathan Piazza
Jonathan S Leff
Justin Chakma
Kathleen D. Scott
Laura Shawver
Maria Koehler
Michael Kelly
Naomi Hunder
Orbimed Advisors Llc
Orbimed Capital Gp Vi Llc
Orbimed Capital Llc
Peter A. Thompson
Peter Kolchinsky
Phillip M Schneider
Powell Andrew Kenneth William
Pratik Shah
Pratik Shah Living Trust Dated June 15, 2011
Presidio Management Group Xii, L.l.c.
Ra Capital Healthcare Fund Lp
Ra Capital Management, L.p.
Ra Capital Nexus Fund Ii, L.p.
Rajeev Dadoo
Rajeev M. Shah
Richard E Lowenthal
Robert Hershberg
Russ Hawkinson

Insider Name	Latest Transaction Date	Aggregate Performance						Aggregate Performance Relative to S&P 500						Companys
Insider Name	Latest Transaction Date	1M	3M	6M	1Y	2Y	3Y	1M	3M	6M	1Y	2Y	3Y	Companys
Insider Name	Latest Transaction Date	Aggregate Performance						Aggregate Performance Relative to S&P 500						Companys
Insider Name	Latest Transaction Date	1M	3M	6M	1Y	2Y	3Y	1M	3M	6M	1Y	2Y	3Y	Companys
Alexander A Fitzpatrick	2023-09-29	14.570	14.570	7.400	27.040	-42.740	-81.400	14.030	39.990	2.120	18.730	-50.780	-91.580	EVFM SBTX SPRY
Alexandria Venture Investments, Llc	2020-09-18	1.870	1.870	31.400	53.140	23.350	20.320	-0.900	-14.620	25.450	40.850	10.060	6.510	MTCR KYMR RLAY RNAM APLT IMRA ... FREQ KRTX IDYA NXTC LQDA CNST EVLO XFOR SBTX VOR VIGL XLO OMIC SPRY ELVN GRNA ENVIU KRRO
Brent L Saunders	2026-03-06	0.000	0.000	-0.050	-8.070	-1.090	3.490	-0.790	-3.900	-6.480	-18.320	-10.240	-7.520	VSPRU BBIO CSCO MRK SKIN DELISTED:MRKPRB.PFD ... SBTX SPRY BLCO
Brian Dorsey	2025-11-13	-	-	-	-	-	-	-	-	-	-	-	-	SEELQ PTXTQ SBTX SPRY
Casey M Tansey	2025-08-01	20.550	20.550	59.000	116.960	72.290	100.630	16.940	29.290	50.740	109.050	68.470	84.080	INSP NARI IMI BOX XENT CSLT ... OMED GWRE MXL ATRC IMPV MEET ONTF SBTX EFTR SPRY CARL SI HTFL
Deerfield Management Company, L.p. (series C)	2021-07-30	-2.400	-2.400	-4.100	-2.800	1.590	-	-5.440	-6.780	-4.930	3.230	-0.520	-	ONCR LRMR CALC AFIB ANNX DFHTU ... NKTX GBIO LUMO DFPHU RVMD SDGR BDTX FIXX DFBHU CABA FREQ MIRM ACRS SWAV XERS ARVN AERI CNST AVDL TARA KNSA MNKKQ CBIO RYTM SCTL EHTH CASM IVTY VNDA ALPN BOLD AXGN SYRS XNPT AVXS EDIT STRM ALIM CTMX ATRS RGNX NEOS ATYR STDY NVTAQ DRNA LOXO ADVM TRIV NXTM RIGL MDCO NURO FCSC NGSX BGMS DVAX VIAP ARNA EWTX AHCO HOWL TOI CMAXQ TERN IGNYU PEPG XLO OMIC NUVL DALS IGNY MCKPF SBTX PKBO FLAC SPRY FLACU KRRO GUTS GYRE QTTB PHGE BCAX
Deerfield Mgmt Iii, L.p.		-	-	-	-	-	-	-	-	-	-	-	-	ONCR CALC AFIB LRMR LUMO FIXX ... SWAV XERS ARVN AERI RYTM TARA BOLD SYRS AVXS EDIT ALIM CTMX RGNX NEOS ATYR STDY ADVM SBTX SPRY GUTS QTTB
Deerfield Mgmt Iv, L.p.		-	-	-	-	-	-	-	-	-	-	-	-	ANNX NKTX LRMR DFPHU RVMD SDGR ... DFBHU CABA FREQ MIRM ARVN TARA EWTX AHCO TOI OMIC NUVL SBTX SPRY KRRO
Deerfield Private Design Fund Iii, L.p.		-	-	-	-	-	-	-	-	-	-	-	-	ONCR CALC AFIB LRMR LUMO FIXX ... SWAV XERS ARVN AERI RYTM TARA BOLD SYRS AVXS EDIT ALIM CTMX RGNX NEOS ATYR STDY ADVM SBTX SPRY GUTS QTTB
Deerfield Private Design Fund Iv, L.p.		-	-	-	-	-	-	-	-	-	-	-	-	ANNX NKTX LRMR DFPHU RVMD SDGR ... DFBHU CABA FREQ MIRM ARVN TARA EWTX AHCO TOI OMIC NUVL SBTX SPRY KRRO
Eric Karas	2025-07-01	-	-	-	-	-	-	-	-	-	-	-	-	SBTX SPRY
James E Flynn	2026-02-27	1.400	1.400	-8.610	-9.270	-14.890	-22.400	0.830	-2.450	-13.340	-20.460	-25.110	-29.650	ONCR LRMR CALC AFIB ANNX DFHTU ... NKTX GBIO LUMO DFPHU RVMD SDGR BDTX FIXX DFBHU CABA FREQ MIRM ACRS SWAV XERS ARVN AERI CNST AVDL TARA KNSA MNKKQ CBIO RYTM SCTL EHTH CASM IVTY VNDA ALPN BOLD AXGN SYRS XNPT AVXS EDIT STRM ALIM CTMX ATRS RGNX NEOS ATYR STDY NVTAQ DRNA LOXO ADVM TRIV NXTM RIGL MDCO NURO FCSC NGSX BGMS DVAX VIAP ARNA EWTX AHCO HOWL TOI CMAXQ TERN IGNYU PEPG XLO OMIC NUVL DALS IGNY MCKPF SBTX PKBO FLAC SPRY FLACU KRRO GUTS GYRE QTTB PHGE BCAX
Jeffrey C. Pepe		-	-	-	-	-	-	-	-	-	-	-	-	SBTX SPRY
Jonathan D Root	2025-07-24	-6.900	-6.900	-9.950	-14.760	-13.930	-11.350	-8.210	-5.990	-14.440	-26.340	-20.850	-20.840	NARI OMED IMI INSP BOX XENT ... CSLT GWRE MXL ATRC IMPV MEET MLNX LDIS SBTX EWTX EFTR SPRY CARL OMDA
Jonathan Piazza	2020-12-08	30.860	30.860	-5.650	-76.950	-	-	27.550	46.220	-19.830	-103.930	-	-	SBTX SPRY
Jonathan S Leff		-	-	-	-	-	-	-	-	-	-	-	-	LRMR TARA AVXS ALPN SNSS VIRX ... SBTX SPRY PHGE
Justin Chakma	2025-11-12	-	-	-	-	-	-	-	-	-	-	-	-	SBTX SPRY
Kathleen D. Scott	2022-11-29	40.730	40.730	22.020	-20.530	54.900	16.460	43.470	50.330	15.760	-35.510	31.480	-3.600	HSTOQ DRMA SBTX SPRY GFOR NKGN
Laura Shawver	2025-04-07	-	-	-	-	-	-	-	-	-	-	-	-	RLAY NKTX THOR SBTX SPRY
Maria Koehler	2025-03-12	-	-	-	-	-	-	-	-	-	-	-	-	RPTX SBTX IKNA SPRY IMA
Michael Kelly		-	-	-	-	-	-	-	-	-	-	-	-	SBTX SPRY
Naomi Hunder		-	-	-	-	-	-	-	-	-	-	-	-	SBTX SPRY
Orbimed Advisors Llc	2025-10-08	3.900	3.900	3.580	2.210	-8.670	-11.950	3.390	5.330	-1.390	-9.360	-20.060	-23.490	ARQT XTNT LOGC CALC PRLD PMVP ... ETNB INSP AFIB PAND FUSN RPTX SCPH ORIC ALEC KROS IMRA CTIC PASG SRRA TCDAQ TELA SWTX CRVS PRVL PRNB NXTC TPTX AVDR ALPN THOR SIBN GH ARVN STDY VRAYQ CNST CRNX ARPO ARMO ADAPY RYTM PIRS BOLD GKOS KALA SYBX LOXO XFOR ROKA SYRE NBRVF RPBIF RLYP RNAC NTLA OTIC DMTX SIENQ ICPT MRTX XLRN SUPN ANTH AMRN PCRX CCXI ATHXQ NXTM KURU ALBO ARYX PODD WHWK NPCE DBTX VRNA SBTX EWTX ACET CMPX THRX KNTE DMRA IRON JANX TERN IKNA THRD SPRY ELVN TSBX PVLA MBX TRAW QTTB AVBP UPB SION STTK IMA
Orbimed Capital Gp Vi Llc		-	-	-	-	-	-	-	-	-	-	-	-	LOGC CALC PRLD ETNB SCPH ORIC ... CTIC SWTX PRVL NXTC TPTX AVDR ALPN ARVN STDY CNST CRNX KALA SYBX NPCE VRNA SBTX EWTX ACET IRON IKNA SPRY TSBX CMPX IMA
Orbimed Capital Llc	2022-03-29	-	-	-	-	-	-	-	-	-	-	-	-	SPRY PMVP ARQT ALEC ELVN PRLD ... RPTX
Peter A. Thompson	2025-04-03	0.150	0.150	3.110	10.780	-5.380	-19.870	-0.820	0.400	-6.390	-3.350	-17.400	-31.500	PMVP PRVL CRVS THOR ALPN PRNB ... ADAPY RPBIF SRRA MRTX ANTH DBTX SBTX EWTX JANX SPRY SION
Peter Kolchinsky	2020-06-23	-10.530	-10.530	-9.150	165.390	-58.080	-	-11.420	9.750	-22.790	138.080	-68.180	-	PCVX CRDF PMVP DYN ETNB TGTX ... INBX WVE INZY ITOS PAND NKTX RACA RYTM AKUS VSTM FMTX RARX PHAT IMRA KALA SCPH THOR DRNA STSA EIGRQ ARVN EIDX KALV GTHX ACRS ACHN SGMO DSCI BSTC ARDMQ SQNM CRIS RXST ABOS VRDN DICE ITRM SLDB ORTX CLYM HOWL ICVX AVTE PNT VOR JANX RACB CTKB PEPG TYRA ANTX FULC SBTX ACRV SPRY ELVN MLYS BDTX SEPN CDTX FDMT BOLD JBIO LENZ ARTV BCAX SION EVMN SGP
Phillip M Schneider	2018-09-11	-11.470	-11.470	-5.030	87.320	59.750	-	-5.950	-14.440	-1.410	83.410	52.200	-	PFNX ARNA LBPH SBTX SPRY
Powell Andrew Kenneth William	2019-01-11	4.420	4.420	-32.690	-40.370	-38.700	-0.650	1.180	-22.660	-40.720	-56.080	-50.450	-19.290	LFCR ACRS THOR MDVN SBTX SPRY
Pratik Shah	2021-03-30	-11.140	-11.140	-50.240	-45.770	-56.060	-48.540	-16.760	-41.180	-59.060	-62.040	-57.220	-58.450	DSGN SBTX SPRY
Pratik Shah Living Trust Dated June 15, 2011		-	-	-	-	-	-	-	-	-	-	-	-	SBTX SPRY
Presidio Management Group Xii, L.l.c.	2020-12-08	30.860	30.860	-5.650	-76.950	-	-	27.550	46.220	-19.830	-103.930	-	-	SBTX SPRY CARL
Ra Capital Healthcare Fund Lp	2026-02-26	8.890	8.890	9.770	15.140	-16.760	-15.620	7.710	3.190	2.210	-0.080	-31.610	-28.960	PCVX ETNB RYTM AKUS VSTM FMTX ... TGTX RARX PHAT IMRA KALA SCPH THOR STSA EIGRQ ARVN EIDX DRNA GTHX KALV ACRS WVE ACHN SGMO DSCI BSTC ARDMQ SQNM CRIS RXST ABOS VRDN DICE ITRM SLDB ORTX CLYM HOWL ICVX NKTX AVTE ITOS PNT VOR JANX CTKB PEPG TYRA ANTX FULC SBTX ACRV SPRY ELVN MLYS BDTX SEPN CDTX FDMT BOLD JBIO LENZ ARTV BCAX SION EVMN SGP
Ra Capital Management, L.p.	2025-11-07	10.000	10.000	22.600	93.150	19.410	-5.900	7.830	17.290	12.560	71.580	4.450	-17.720	PCVX CRDF PMVP DYN ETNB TGTX ... INBX INZY ITOS PAND NKTX RYTM AKUS VSTM FMTX RARX PHAT IMRA KALA SCPH THOR STSA WVE EIGRQ ARVN EIDX DRNA KALV GTHX ACRS ACHN SGMO DSCI BSTC ARDMQ SQNM CRIS RXST ABOS VRDN DICE ITRM SLDB ORTX CLYM HOWL ICVX AVTE PNT VOR JANX CTKB PEPG TYRA ANTX FULC SBTX ACRV SPRY ELVN MLYS BDTX SEPN CDTX FDMT BOLD JBIO LENZ ARTV BCAX SION EVMN SGP
Ra Capital Nexus Fund Ii, L.p.		-	-	-	-	-	-	-	-	-	-	-	-	ABOS DICE CLYM ICVX CTKB PEPG ... ANTX SBTX ACRV SPRY JANX BOLD HOWL LENZ
Rajeev Dadoo		-	-	-	-	-	-	-	-	-	-	-	-	SBTX SPRY
Rajeev M. Shah	2020-03-13	10.660	10.660	20.060	35.070	-4.130	-20.240	11.720	1.980	16.270	21.920	-16.880	-31.070	PCVX CRDF PMVP DYN ETNB TGTX ... INBX INZY ITOS PAND NKTX RYTM AKUS KALA VSTM FMTX SLDB STSA EIDX RARX PHAT IMRA SCPH BDTX THOR KALV RXST ABOS VRDN WVE DICE ITRM ORTX CLYM HOWL ICVX AVTE PNT VOR JANX CTKB PEPG TYRA ANTX FULC SBTX ACRV SPRY ELVN MLYS SEPN CDTX FDMT BOLD JBIO LENZ ARTV BCAX SION EVMN SGP
Richard E Lowenthal	2025-08-21	-	-	-	-	-	-	-	-	-	-	-	-	SBTX SPRY
Robert Hershberg	2025-12-10	-	-	-	-	-	-	-	-	-	-	-	-	NSTGQ ADPT FATE RXRX SBTX HLVX ... SPRY ATAI
Russ Hawkinson	2020-12-08	30.860	30.860	-5.650	-76.950	-	-	27.550	46.220	-19.830	-103.930	-	-	SBTX SPRY

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Total 47

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