Karyopharm Therapeutics Inc logo

Karyopharm Therapeutics Inc

NEW
NAS:KPTI (USA)  
$ 9.54 -0.20 (-2.1%) 08:08 PM EST
At Loss
Market Cap:
$ 216.20M
Enterprise V:
$ 356.23M
Volume:
308.24K
Avg Vol (2M):
494.71K
Trade In:
Volume:
308.24K
At Loss
Avg Vol (2M):
494.71K

Business Description

Karyopharm Therapeutics Inc logo
Karyopharm Therapeutics Inc
NAICS : 325412 SIC : 5999
ISIN : US48576U2050

Total Employee Number:

228
Description
Karyopharm Therapeutics Inc is a commercial-stage pharmaceutical company focused on novel cancer therapies and dedicated to the discovery, development, and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. The company conducts research focused on intracellular communication between the nucleus and cytoplasm and has developed small-molecule compounds that inhibit exportin 1 (XPO1), a nuclear export protein. It is focused on marketing XPOVIO (selinexor).
Name Current Vs Industry Vs History
Cash-To-Debt
0.39
Equity-to-Asset
-2.02
Debt-to-Equity
-0.87
Debt-to-EBITDA
-1.57
Piotroski F-Score
2/9
0
1
2
3
4
5
6
7
8
9
Altman Z-Score
-21.13
Distress
Grey
Safe
Beneish M-Score
-5.57
Manipulator
Not Manipulator
WACC vs ROIC
WACC
ROIC
Name Current Vs Industry Vs History
5-Day RSI
47.77
9-Day RSI
52.16
14-Day RSI
53.42
3-1 Month Momentum %
68.73
6-1 Month Momentum %
33.42
12-1 Month Momentum %
125.23

Liquidity Ratio

Name Current Vs Industry Vs History
Current Ratio
1.08
Quick Ratio
1.05
Cash Ratio
0.77
Days Inventory
260.23
Days Sales Outstanding
72.26
Days Payable
269.72

Dividend & Buy Back

Name Current Vs Industry Vs History
3-Year Average Share Buyback Ratio
-34.4
Shareholder Yield %
-32.53
Name Current Vs Industry Vs History
Gross Margin %
96.03
Operating Margin %
-55.73
Net Margin %
-129.02
EBITDA Margin %
-97.49
FCF Margin %
-39.12
OCF Margin %
-39.12
ROA %
-171.43
ROIC %
-244.18
3-Year ROIIC %
-947.64
ROC (Joel Greenblatt) %
-2941.88
ROCE %
-893.72
Moat Score
4
Tariff Resilience Score
7

Financials (Next Earnings Date:2026-08-11 Est.)

KPTI's 30-Y Financials
Income Statement Breakdown FY
Not Enough Data
Balance Sheet Breakdown
Not Enough Data
Cashflow Statement Breakdown
Not Enough Data

Operating Revenue by Business Segment

Operating Revenue by Geographic Region

Historical Operating Revenue by Business Segment

Historical Operating Revenue by Geographic Region

5-Step DuPont Analysis as of
Not Enough Data

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Peter Lynch Chart

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Performance

Dividend
Log
Bar
To

Annualized Return %  

Symbol
1 Week
1 Month
3 Months
6 Months
YTD
1 Year
3 Years
5 Years
10 Years

Total Annual Return %  

Symbol
2026
2025
2024
2023
2022
2021
2020
2019
2018
2017

Karyopharm Therapeutics Inc Executives

Details

Valuation Chart

Year:

Analyst Estimate

Key Statistics

Name Value
Revenue (TTM) (Mil $) 151.118
EPS (TTM) ($) -15.09
Beta 2.0403
3-Year Sharpe Ratio 0.06
3-Year Sortino Ratio 0.11
Volatility % 121.13
14-Day RSI 53.42
14-Day ATR ($) 0.731072
20-Day SMA ($) 9.29725
12-1 Month Momentum % 125.23
52-Week Range ($) 3.6503 - 10.99
Shares Outstanding (Mil) 22.66

Piotroski F-Score Details

Year:
Component Result
Piotroski F-Score 2
Positive ROA
Positive CFROA
Higher ROA yoy
CFROA > ROA
Lower Leverage yoy
Higher Current Ratio yoy
Less Shares Outstanding yoy
Higher Gross Margin yoy
Higher Asset Turnover yoy

Karyopharm Therapeutics Inc Filings

Filing Date Document Date Form
No Filing Data

Karyopharm Therapeutics Inc Stock Events

Financials Calendars
Event Date Price ($)
Third quarter earnings conference call for 2026 2026-11-03 08:00 In 125 days
Third quarter earnings results for 2026 2026-11-03 In 124 days
Second quarter earnings conference call for 2026 2026-08-11 08:00 In 41 days
Second quarter earnings results for 2026 2026-08-11 In 40 days
Guidance call for 2026 2026-06-04 08:10 9.00 (-0.88%)
Guidance call for 2026 2026-06-02 14:00 9.82 (+7.32%)
General meeting for 2026 2026-05-21 09:00 7.98 (+8.13%)
Guidance call for 2026 2026-05-19 15:35 7.14 (-6.79%)
First quarter earnings conference call for 2026 2026-05-14 08:00 8.85 (-1.56%)
First quarter earnings results for 2026 2026-05-14 8.85 (-1.56%)
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Karyopharm Therapeutics Inc Frequently Asked Questions

What is Karyopharm Therapeutics Inc(KPTI)'s stock price today?
The current price of KPTI is $9.54. The 52 week high of KPTI is $10.99 and 52 week low is $3.65.
When is next earnings date of Karyopharm Therapeutics Inc(KPTI)?
The next earnings date of Karyopharm Therapeutics Inc(KPTI) is 2026-08-11 Est..
Does Karyopharm Therapeutics Inc(KPTI) pay dividends? If so, how much?
Karyopharm Therapeutics Inc(KPTI) does not pay dividend.

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