Business Description
Karyopharm Therapeutics Inc
NAICS : 325412
SIC : 5999
ISIN : US48576U2050
Total Employee Number:
228Compare
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Traded in other countries / regions
KPTI.USA25K0.Germany Index Membership
Russell 3000Russell 2000 IPO Date
2013-11-06Description
Karyopharm Therapeutics Inc is a commercial-stage pharmaceutical company focused on novel cancer therapies and dedicated to the discovery, development, and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. The company conducts research focused on intracellular communication between the nucleus and cytoplasm and has developed small-molecule compounds that inhibit exportin 1 (XPO1), a nuclear export protein. It is focused on marketing XPOVIO (selinexor).
Financial Strength
1/10
| Name | Current | Vs Industry | Vs History | |||
|---|---|---|---|---|---|---|
Cash-To-Debt | 0.25 | |||||
Equity-to-Asset | -2.97 | |||||
Debt-to-Equity | -0.78 | |||||
Debt-to-EBITDA | -1.46 | |||||
Piotroski F-Score | 2/9 | |||||
Altman Z-Score | -27.39 | |||||
Beneish M-Score | -5.5 | |||||
WACC vs ROIC | ||||||
Growth Rank
6/10
| Name | Current | Vs Industry | Vs History | |||
|---|---|---|---|---|---|---|
3-Year Revenue Growth Rate | -22.6 | |||||
3-Year EBITDA Growth Rate | 18.7 | |||||
3-Year EPS without NRI Growth Rate | 23.8 | |||||
3-Year FCF Growth Rate | 36.9 | |||||
3-Year Book Growth Rate | -93.5 | |||||
Future 3-5Y EPS without NRI Growth Rate Estimate Industry Rank | 57.43 | |||||
Future 3-5Y Total Revenue Growth Rate Estimate | 14.26 |
Momentum Rank
2/10
| Name | Current | Vs Industry | Vs History | |||
|---|---|---|---|---|---|---|
5-Day RSI | 22.17 | |||||
9-Day RSI | 25.98 | |||||
14-Day RSI | 25.53 | |||||
3-1 Month Momentum % | -76.67 | |||||
6-1 Month Momentum % | -76 | |||||
12-1 Month Momentum % | -68.37 |
Liquidity Ratio
| Name | Current | Vs Industry | Vs History | |||
|---|---|---|---|---|---|---|
Current Ratio | 0.79 | |||||
Quick Ratio | 0.76 | |||||
Cash Ratio | 0.49 | |||||
Days Inventory | 249.38 | |||||
Days Sales Outstanding | 71.8 | |||||
Days Payable | 289.86 |
Dividend & Buy Back
| Name | Current | Vs Industry | Vs History | |||
|---|---|---|---|---|---|---|
3-Year Average Share Buyback Ratio | -34.4 | |||||
Shareholder Yield % | -239.44 |
Profitability Rank
1/10
| Name | Current | Vs Industry | Vs History | |||
|---|---|---|---|---|---|---|
Gross Margin % | 95.89 | |||||
Operating Margin % | -56.17 | |||||
Net Margin % | -153.28 | |||||
EBITDA Margin % | -119.56 | |||||
FCF Margin % | -44.57 | |||||
OCF Margin % | -44.57 | |||||
ROA % | -203.47 | |||||
ROIC % | -216.29 | |||||
3-Year ROIIC % | -947.64 | |||||
ROC (Joel Greenblatt) % | -3711.93 | |||||
ROCE % | -3935.05 | |||||
Moat Score | 4 | |||||
Tariff Resilience Score | 7 |
GF Value Rank
2/10
| Name | Current | Vs Industry | Vs History | |||
|---|---|---|---|---|---|---|
PS Ratio | 0.22 | |||||
EV-to-EBIT | -1.3 | |||||
EV-to-EBITDA | -1.3 | |||||
EV-to-Revenue | 1.55 | |||||
EV-to-Forward-Revenue | 1.15 | |||||
EV-to-FCF | -3.48 | |||||
Price-to-GF-Value | 0.35 | |||||
Price-to-Median-PS-Value | 0.03 | |||||
Earnings Yield (Greenblatt) % | -76.92 | |||||
FCF Yield % | -178.93 |
Operating Revenue by Business Segment
Operating Revenue by Geographic Region
Historical Operating Revenue by Business Segment
Historical Operating Revenue by Geographic Region
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Performance
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Annualized Return % Â
Total Annual Return % Â
Karyopharm Therapeutics Inc Executives
DetailsAnalyst Estimate
Key Statistics
| Name | Value | ||
|---|---|---|---|
| Revenue (TTM) (Mil $) | 146.621 | ||
| EPS (TTM) ($) | -13.09 | ||
| Beta | 2.2668 | ||
| 3-Year Sharpe Ratio | 0.01 | ||
| 3-Year Sortino Ratio | 0.02 | ||
| Volatility % | 123.54 | ||
| 14-Day RSI | 25.53 | ||
| 14-Day ATR ($) | 0.261837 | ||
| 20-Day SMA ($) | 1.8685 | ||
| 12-1 Month Momentum % | -68.37 | ||
| 52-Week Range ($) | 1.24 - 10.99 | ||
| Shares Outstanding (Mil) | 22.68 |
Piotroski F-Score Details
Year:
| Component | Result | ||
|---|---|---|---|
| Piotroski F-Score | 2 | ||
| Positive ROA | |||
| Positive CFROA | |||
| Higher ROA yoy | |||
| CFROA > ROA | |||
| Lower Leverage yoy | |||
| Higher Current Ratio yoy | |||
| Less Shares Outstanding yoy | |||
| Higher Gross Margin yoy | |||
| Higher Asset Turnover yoy |
Karyopharm Therapeutics Inc Filings
| Filing Date | Document Date | Form | ||
|---|---|---|---|---|
| No Filing Data | ||||
Karyopharm Therapeutics Inc Stock Events
| Event | Date | Price ($) | ||
|---|---|---|---|---|
| Fourth quarter earnings conference call for 2026 | 2027-02-12 08:00 | In 154 days | ||
| Annual report for 2026 | 2027-02-12 | In 153 days | ||
| Fourth quarter earnings results for 2026 | 2027-02-12 | In 153 days | ||
| Third quarter earnings conference call for 2026 | 2026-11-03 08:00 | In 53 days | ||
| Third quarter earnings results for 2026 | 2026-11-03 | In 52 days | ||
| Second quarter earnings conference call for 2026 | 2026-08-13 08:00 | 2.03 (-3.33%) | ||
| Second quarter earnings results for 2026 | 2026-08-13 | 2.03 (-3.33%) | ||
| Guidance call for 2026 | 2026-06-04 08:10 | 9.00 (-0.88%) | ||
| Guidance call for 2026 | 2026-06-02 14:00 | 9.82 (+7.32%) | ||
| General meeting for 2026 | 2026-05-21 09:00 | 7.98 (+8.13%) |
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Karyopharm Therapeutics Inc Frequently Asked Questions
What is Karyopharm Therapeutics Inc(KPTI)'s stock price today?
The current price of KPTI is $1.61. The 52 week high of KPTI is $10.99 and 52 week low is $1.24.
When is next earnings date of Karyopharm Therapeutics Inc(KPTI)?
The next earnings date of Karyopharm Therapeutics Inc(KPTI) is 2026-11-03 Est..
Does Karyopharm Therapeutics Inc(KPTI) pay dividends? If so, how much?
Karyopharm Therapeutics Inc(KPTI) does not pay dividend.
Press Release
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Sep 02, 2026
Short Interest Alert: Most and least shorted sub-$2B healthcare stocks in Aug 2026
Seeking Alpha • 9:15am
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