Ionis Pharmaceuticals (LTS:0JDI) Beginning Cash Position: $372 Mil (As of Mar. 2026)

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LTS:0JDI Ionis Pharmaceuticals Inc LTS:0JDI
67 GF Score
Price $53.22
GF Value $52.67
Valuation Fairly Valued
! 6 Warning Signs
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What is Ionis Pharmaceuticals Beginning Cash Position?

Ionis Pharmaceuticals LTS:0JDI -0.33% 67 Beginning Cash Position is $372 Mil as of Mar. 2026. GuruFocus rates LTS:0JDI with a GF Score™ of 67/100 and a GF Value™ of $52.67 (Fairly Valued). The stock has 6 warning signs investors should review.

Ionis Pharmaceuticals's Beginning Cash Position for the quarter that ended in Mar. 2026 was $372 Mil.

Ionis Pharmaceuticals's quarterly Beginning Cash Position increased from Sep. 2025 ($297 Mil) to Dec. 2025 ($338 Mil) and increased from Dec. 2025 ($338 Mil) to Mar. 2026 ($372 Mil).

Ionis Pharmaceuticals's annual Beginning Cash Position increased from Dec. 2023 ($276 Mil) to Dec. 2024 ($399 Mil) but then declined from Dec. 2024 ($399 Mil) to Dec. 2025 ($242 Mil).

Ionis Pharmaceuticals Beginning Cash Position Related Terms

Ionis Pharmaceuticals Beginning Cash Position Historical Data

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The historical data trend for Ionis Pharmaceuticals's Beginning Cash Position can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Ionis Pharmaceuticals Beginning Cash Position Chart

Ionis Pharmaceuticals Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Beginning Cash Position
Get a 7-Day Free Trial Premium Member Only Premium Member Only 397.66 869.19 276.47 399.27 242.08

Ionis Pharmaceuticals Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Beginning Cash Position Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 242.08 264.19 297.30 338.34 372.26
LTS:0JDI
67GF Score
Ionis Pharmaceuticals Inc LTS:0JDI
Beginning Cash Position is just one metric. See GF Score™, valuation, warning signs, and more.
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Ionis Pharmaceuticals Beginning Cash Position Calculation

Beginning Cash Position is the cash and equivalents balance at the beginning of the accounting period, as indicated on the Cash Flow statement.

What does a Beginning Cash Position of $372 Mil mean?
Ionis Pharmaceuticals (LTS:0JDI) has a Beginning Cash Position of $372 Mil as of Mar. 2026. Beginning Cash Position is the cash and equivalents balance at the beginning of the accounting period, as indicated on the Cash Flow statement. View historical data on Ionis Pharmaceuticals and its competitors.
Is Ionis Pharmaceuticals' Beginning Cash Position too high?
Ionis Pharmaceuticals' current Beginning Cash Position is $372 Mil. Overall, Ionis Pharmaceuticals has a GF Score™ of 67/100 and is considered Fairly Valued, reflecting its overall financial health beyond just this single metric.
How does Ionis Pharmaceuticals' Beginning Cash Position compare to EXEL and BBIO?
Ionis Pharmaceuticals' Beginning Cash Position of $372 Mil can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Beginning Cash Position for a Biotechnology company?
A good Beginning Cash Position depends on the Biotechnology industry context. However, Beginning Cash Position should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Beginning Cash Position mean?
A high Beginning Cash Position can signal that a stock is expensive relative to its fundamentals. Beginning Cash Position is the cash and equivalents balance at the beginning of the accounting period, as indicated on the Cash Flow statement. View historical data on Ionis Pharmaceuticals and its competitors. Ionis Pharmaceuticals's current Beginning Cash Position is $372 Mil. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Ionis Pharmaceuticals stock overvalued right now?
Based on GuruFocus' analysis, Ionis Pharmaceuticals (LTS:0JDI) is currently considered Fairly Valued. The stock's GF Value™ is $52.67, compared to a current price of $53.22 — trading 1% above its estimated fair value. The current Beginning Cash Position is $372 Mil. Ionis Pharmaceuticals' overall GF Score™ is 67/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Beginning Cash Position calculated?
Beginning Cash Position is calculated from a company's financial statements. For Ionis Pharmaceuticals (LTS:0JDI), the current Beginning Cash Position is $372 Mil as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Ionis Pharmaceuticals (LTS:0JDI) Overvalued in 2026?

Based on GuruFocus' analysis, Ionis Pharmaceuticals stock appears to be overvalued. The current stock price of $53.22 is trading 1% above its estimated GF Value™ of $52.67. GuruFocus considers Ionis Pharmaceuticals to be Fairly Valued.

Key valuation signals for LTS:0JDI:

  • Beginning Cash Position: $372 Mil
  • GF Value™: $52.67 vs. price of $53.22 (1% above fair value)
  • GF Score™: 67/100 with 6 warning signs

No single metric tells the full story. See the LTS:0JDI stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.

Ionis Pharmaceuticals Business Description

Address 2855 Gazelle Court, Carlsbad, CA, USA, 92010
Ionis Pharmaceuticals is the leading developer of antisense technology to discover and develop novel drugs. Its broad clinical and preclinical pipeline targets a wide variety of diseases, with an emphasis on cardiovascular, metabolic, neurological, and rare diseases. Ionis and Biogen brought Spinraza to market in 2016 as a treatment for spinal muscular atrophy, and Biogen launched ALS drug Qalsody in 2023. Ionis brought two additional drugs to market via its cardiovascular-focused subsidiary Akcea, including ATTR amyloidosis drug Tegsedi (2018) and cardiology drug Waylivra (Europe, 2019). Ionis and AstraZeneca launched polyneuropathy drug Wainua in 2024. Ionis marked its first two independent launches in 2025 for Tryngolza (for FCS) and Dawnzera (for HAE).
67GF Score

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Beginning Cash Position is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$53.22
Price
$52.67
GF Value