ANRO (Alto Neuroscience) Buyback Yield %: -12.43 (As of Jul. 01, 2026)


ANRO Alto Neuroscience Inc ANRO
12 GF Score
Price $26.39
! 2 Warning Signs
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What is Alto Neuroscience Buyback Yield %?

Alto Neuroscience ANRO -5.99% 12 Buyback Yield % is -12.43 as of Jul. 01, 2026. GuruFocus rates ANRO with a GF Score™ of 12/100. The stock has 2 warning signs investors should review. Among 745 Biotechnology companies, Alto Neuroscience ranks worse than 55.03% on this metric.

Buyback yield is the net repurchase of shares outstanding over the market capital of the company. It is a measure of shareholder return.

Alto Neuroscience's current buyback yield was -12.43%.

Alto Neuroscience Buyback Yield % Historical Data

* Premium members only.

The historical data trend for Alto Neuroscience's Buyback Yield % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Alto Neuroscience Buyback Yield % Chart

Alto Neuroscience Annual Data
Trend Dec21 Dec22 Dec23 Dec24 Dec25
Buyback Yield %
0.00 0.00 0.00 -120.52 -8.77

Alto Neuroscience Quarterly Data
Dec21 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Buyback Yield % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 0.00 -8.77 -14.61

ANRO vs SANA, AVTX, REPL: Buyback Yield % Comparison

For the Biotechnology subindustry, Alto Neuroscience's Buyback Yield %, along with its competitors' market caps and Buyback Yield % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.

Alto Neuroscience Buyback Yield % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Alto Neuroscience's Buyback Yield % distribution charts can be found below:

* The bar in red indicates where Alto Neuroscience's Buyback Yield % falls into.


ANRO
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Alto Neuroscience Inc ANRO
Buyback Yield % is just one metric. See GF Score™, valuation, warning signs, and more.
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Alto Neuroscience Buyback Yield % Calculation

Buyback yield is a measure of shareholder return.

Alto Neuroscience's Buyback Yield for the fiscal year that ended in Dec. 2025 is calculated as

Buyback Yield=Net Issuance of Stock / Market Cap
=- (Repurchase of Stock + Issuance of Stock) / Market Cap
=- (-0.167 + 50) / 568.2472
=-8.77%

Alto Neuroscience's annualized Buyback Yield for the quarter that ended in Mar. 2026 is calculated as

Buyback Yield=Net Issuance of Stock(TTM) / Market Cap
=- (Repurchase of Stock + Issuance of Stock) (TTM)** / Market Cap
=- (-4.875 + 120) / 787.99144
=-14.61%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

** If the quarter corresponds to the year-end period, we will use the annual Repurchase of Stock and Issuance of Stock data .

Frequently Asked Questions Learn more about Buyback Yield % →
What does a Buyback Yield % of -12.43 mean?
Alto Neuroscience (ANRO) has a Buyback Yield % of -12.43 as of Jul. 01, 2026. Share buyback yield equals the net issuance of stock divided by market cap. View historical data on Alto Neuroscience and its competitors. According to the industry distribution chart, Alto Neuroscience ranks #410 out of 745 companies in the Biotechnology industry, placing it in the top 55%.
Is Alto Neuroscience's Buyback Yield % too high?
Alto Neuroscience's current Buyback Yield % is -12.43. Based on the distribution chart, Alto Neuroscience ranks #410 out of 745 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Alto Neuroscience has a GF Score™ of 12/100, reflecting its overall financial health beyond just this single metric.
How does Alto Neuroscience's Buyback Yield % compare to SANA and AVTX?
According to the Biotechnology industry distribution chart, Alto Neuroscience ranks #410 out of 745 companies for Buyback Yield %. This places Alto Neuroscience in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Buyback Yield % for a Biotechnology company?
A good Buyback Yield % depends on the Biotechnology industry context. However, Buyback Yield % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Buyback Yield % mean?
A high Buyback Yield % can signal that a stock is expensive relative to its fundamentals. Share buyback yield equals the net issuance of stock divided by market cap. View historical data on Alto Neuroscience and its competitors. Alto Neuroscience's current Buyback Yield % is -12.43. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Alto Neuroscience stock overvalued right now?
Alto Neuroscience (ANRO) has a current Buyback Yield % of -12.43. The current Buyback Yield % is -12.43. Alto Neuroscience's overall GF Score™ is 12/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Buyback Yield % calculated?
Buyback Yield % is calculated from a company's financial statements. For Alto Neuroscience (ANRO), the current Buyback Yield % is -12.43 as of Jul. 01, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Alto Neuroscience Business Description

Address 650 Castro Street, Suite 450, Mountain View, CA, USA, 94041
Alto Neuroscience Inc is a clinical-stage biopharmaceutical company with a mission to redefine psychiatry by leveraging individual's neurobiology to develop personalized and effective treatment options. The company currently consists of different clinical-stage assets such as ALTO-100, ALTO-202, ALTO-207, ALTO-101, and ALTO-300 among others initially targeting depressive disorders and schizophrenia populations as identified by independent brain-based biomarkers.
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