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Alto NeuroscienceANRO +3.52%12 EV-to-OCF is -13.75 as of Aug. 04, 2026. GuruFocus rates ANRO with a GF Score™ of 12/100. The stock has 2 warning signs investors should review. Among 1,411 Biotechnology companies, Alto Neuroscience ranks better than 74.98% on this metric.
EV-to-OCF is calculated as enterprise value divided by its cash flow from operations. As of today, Alto Neuroscience's Enterprise Value is $856.76 Mil.
Alto Neuroscience's Cash Flow from Operations for the trailing twelve months (TTM) ended in Mar. 2026 was $-62.30 Mil. Therefore, Alto Neuroscience's EV-to-OCF for today is -13.75.
The historical rank and industry rank for Alto Neuroscience's EV-to-OCF or its related term are showing as below:
ANRO'
s EV-to-OCF Range Over the Past 10 Years
Min: -13.92 Med: 0 Max: -13.09
Current: -13.75
During the past 5 years, the highest EV-to-OCF of Alto Neuroscience was -13.09. The lowest was -13.92. And the median was .
ANRO's EV-to-OCF is ranked better than 74.98% of 1411
companies
in the Biotechnology industry
Industry Median: -3.32
vs ANRO: -13.75
EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
Alto Neuroscience's PE Ratio (TTM) for today is calculated as:
Alto Neuroscience's share price for today is $28.23.
Alto Neuroscience's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-2.420.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Enterprise Value is used because it is a more complete measure in reflecting how much an investor pays when buying a company. Cash Flow from Operations is an important financial metric because it represents the cash generated from operating activities at a company's disposal. Companies with a low EV-to-OCF ratio, combined with a strong balance sheet are generally considered as undervalued.
Alto Neuroscience EV-to-OCF Related Terms
Alto Neuroscience EV-to-OCF Historical Data
* Premium members only.
The historical data trend for Alto Neuroscience's EV-to-OCF can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Biotechnology subindustry, Alto Neuroscience's EV-to-OCF, along with its competitors' market caps and EV-to-OCF data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Alto Neuroscience EV-to-OCF vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Alto Neuroscience's EV-to-OCF distribution charts can be found below:
* The bar in red indicates where Alto Neuroscience's EV-to-OCF falls into.
Alto Neuroscience's current Enterprise Value is $856.76 Mil.
Alto Neuroscience's Cash Flow from Operations for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-62.30 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Alto Neuroscience (ANRO) has a EV-to-OCF of -13.75 as of Aug. 04, 2026. According to the industry distribution chart, Alto Neuroscience ranks #353 out of 1411 companies in the Biotechnology industry, placing it in the top 25%.
Is Alto Neuroscience's EV-to-OCF too high?
Alto Neuroscience's current EV-to-OCF is -13.75. Based on the distribution chart, Alto Neuroscience ranks #353 out of 1411 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Alto Neuroscience has a GF Score™ of 12/100, reflecting its overall financial health beyond just this single metric.
How does Alto Neuroscience's EV-to-OCF compare to VOR and CGEM?
According to the Biotechnology industry distribution chart, Alto Neuroscience ranks #353 out of 1411 companies for EV-to-OCF. This places Alto Neuroscience in the top 25% of its industry — outperforming the majority of peers. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-OCF for a Biotechnology company?
A good EV-to-OCF depends on the Biotechnology industry context. However, EV-to-OCF should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-OCF mean?
A high EV-to-OCF can signal that a stock is expensive relative to its fundamentals. Alto Neuroscience's current EV-to-OCF is -13.75. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Alto Neuroscience stock overvalued right now?
Alto Neuroscience (ANRO) has a current EV-to-OCF of -13.75. The current EV-to-OCF is -13.75. Alto Neuroscience's overall GF Score™ is 12/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-OCF calculated?
EV-to-OCF is calculated from a company's financial statements. For Alto Neuroscience (ANRO), the current EV-to-OCF is -13.75 as of Aug. 04, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Alto Neuroscience Inc is a clinical-stage biopharmaceutical company with a mission to redefine psychiatry by leveraging individual's neurobiology to develop personalized and effective treatment options. The company currently consists of different clinical-stage assets such as ALTO-100, ALTO-202, ALTO-207, ALTO-101, and ALTO-300 among others initially targeting depressive disorders and schizophrenia populations as identified by independent brain-based biomarkers.
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