Macrogenics (FRA:M55) Cyclically Adjusted Book per Share: €4.45 (As of Mar. 2026)


FRA:M55 Macrogenics Inc FRA:M55
47 GF Score
Price €4.12
GF Value €3.59
Valuation Modestly Overvalued
! 8 Warning Signs
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What is Macrogenics Cyclically Adjusted Book per Share?

Macrogenics FRA:M55 +4.04% 47 Cyclically Adjusted Book per Share is €4.45 as of Mar. 2026. GuruFocus rates FRA:M55 with a GF Score™ of 47/100 and a GF Value™ of €3.59 (Modestly Overvalued). The stock has 8 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Book per Share and the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years.

Macrogenics's adjusted book value per share for the three months ended in Mar. 2026 was €0.288. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is €4.45 for the trailing ten years ended in Mar. 2026.

During the past 12 months, Macrogenics's average Cyclically Adjusted Book Growth Rate was -14.40% per year. During the past 3 years, the average Cyclically Adjusted Book Growth Rate was -5.20% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the Cyclically Adjusted Book Growth Rate using Cyclically Adjusted Book per Share data.

During the past 13 years, the highest 3-Year average Cyclically Adjusted Book Growth Rate of Macrogenics was -5.20% per year. The lowest was -5.20% per year. And the median was -5.20% per year.

As of today (2026-07-09), Macrogenics's current stock price is €4.12. Macrogenics's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 was €4.45. Macrogenics's Cyclically Adjusted PB Ratio of today is 0.93.

During the past 13 years, the highest Cyclically Adjusted PB Ratio of Macrogenics was 2.82. The lowest was 0.17. And the median was 0.64.


Macrogenics  (FRA:M55) Cyclically Adjusted Book per Share Explanation

If a company grows much fast than inflation, Cyclically Adjusted Book per Share may underestimate the company's equity. Cyclically Adjusted PB Ratio can seem to be too high even the actual PB Ratio is low.

For the Cyclically Adjusted PB Ratio, the book value of the past 10 years are inflation-adjusted and averaged. The result is used for P/B calculation. Since it looks at the average over the last 10 years, the Cyclically Adjusted PB Ratio is also called CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Macrogenics's Cyclically Adjusted PB Ratio of today is calculated as

Cyclically Adjusted PB Ratio=Share Price/Cyclically Adjusted Book per Share
=4.12/4.45
=0.93

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

During the past 13 years, the highest Cyclically Adjusted PB Ratio of Macrogenics was 2.82. The lowest was 0.17. And the median was 0.64.


Be Aware

Cyclically Adjusted PB Ratio works better for cyclical companies. It gives you a better idea on the company's real book value.


Macrogenics Cyclically Adjusted Book per Share Related Terms


Macrogenics Cyclically Adjusted Book per Share Historical Data

* Premium members only.

The historical data trend for Macrogenics's Cyclically Adjusted Book per Share can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Macrogenics Cyclically Adjusted Book per Share Chart

Macrogenics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted Book per Share
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 5.89 6.28 6.04 4.54

Macrogenics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted Book per Share Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 5.65 5.16 5.15 4.54 4.45

FRA:M55 vs IMRX, TRDA, SLNCF: Cyclically Adjusted Book per Share Comparison

For the Biotechnology subindustry, Macrogenics's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Macrogenics Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Macrogenics's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Macrogenics's Cyclically Adjusted PB Ratio falls into.


FRA:M55
47GF Score
Macrogenics Inc FRA:M55
Cyclically Adjusted Book per Share is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Macrogenics Cyclically Adjusted Book per Share Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Book per Share and the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years.

What is Cyclically Adjusted Book per Share? How do we calculate Cyclically Adjusted Book per Share?

Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the Cyclically Adjusted Book per Share of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the book value per share from 2001 through 2010.

We adjusted the 2001 book value per share data with the total inflation from 2001 through 2010 to the equivalent book value in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart's book value is $1 a share in 2001, then the 2001's equivalent book value in 2010 is $1.4 a share. If Wal-Mart's book value is $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 book value in 2010 is $1.35. So on and so forth, you get the equivalent book value per share of past 10 years. Then you add them together and divided the sum by the count to get Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, Macrogenics's adjusted Book Value per Share data for the three months ended in Mar. 2026 was:

Adj_Book= Book Value per Share /CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=0.288/330.2130*330.2130
=0.288

Current CPI (Mar. 2026) = 330.2130.

Macrogenics Quarterly Data

Book Value per Share CPI Adj_Book
201606 8.465 241.018 11.598
201609 7.681 241.428 10.506
201612 7.306 241.432 9.993
201703 6.272 243.801 8.495
201706 5.613 244.955 7.567
201709 4.319 246.819 5.778
201712 6.860 246.524 9.189
201803 5.416 249.554 7.167
201806 6.325 251.989 8.288
201809 5.733 252.439 7.499
201812 5.041 251.233 6.626
201903 5.814 254.202 7.552
201906 5.330 256.143 6.871
201909 4.737 256.759 6.092
201912 4.240 256.974 5.448
202003 3.510 258.115 4.490
202006 4.123 257.797 5.281
202009 4.407 260.280 5.591
202012 4.324 260.474 5.482
202103 4.907 264.877 6.117
202106 4.404 271.696 5.353
202109 4.044 274.310 4.868
202112 3.459 278.802 4.097
202203 2.638 287.504 3.030
202206 2.193 296.311 2.444
202209 2.021 296.808 2.248
202212 2.173 296.797 2.418
202303 1.650 301.836 1.805
202306 2.556 305.109 2.766
202309 2.930 307.789 3.143
202312 2.255 306.746 2.428
202403 1.561 312.332 1.650
202406 0.856 314.175 0.900
202409 1.724 315.301 1.806
202412 1.764 315.605 1.846
202503 1.160 319.799 1.198
202506 0.639 322.561 0.654
202509 0.902 324.800 0.917
202512 0.750 324.054 0.764
202603 0.288 330.213 0.288

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

What does a Cyclically Adjusted Book per Share of €4.45 mean?
Macrogenics (FRA:M55) has a Cyclically Adjusted Book per Share of €4.45 as of Mar. 2026. Cyclically adjusted book value per share represents the company's inflation-adjusted book value per share over a 10-year period. View historical data on Macrogenics and its competitors.
Is Macrogenics' Cyclically Adjusted Book per Share too high?
Macrogenics' current Cyclically Adjusted Book per Share is €4.45. Overall, Macrogenics has a GF Score™ of 47/100 and is considered Modestly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Macrogenics' Cyclically Adjusted Book per Share compare to IMRX and TRDA?
Macrogenics' Cyclically Adjusted Book per Share of €4.45 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted Book per Share for a Biotechnology company?
A good Cyclically Adjusted Book per Share depends on the Biotechnology industry context. However, Cyclically Adjusted Book per Share should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted Book per Share mean?
A high Cyclically Adjusted Book per Share can signal that a stock is expensive relative to its fundamentals. Cyclically adjusted book value per share represents the company's inflation-adjusted book value per share over a 10-year period. View historical data on Macrogenics and its competitors. Macrogenics's current Cyclically Adjusted Book per Share is €4.45. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Macrogenics stock overvalued right now?
Based on GuruFocus' analysis, Macrogenics (FRA:M55) is currently considered Modestly Overvalued. The stock's GF Value™ is €3.59, compared to a current price of €4.12 — trading 14.8% above its estimated fair value. The current Cyclically Adjusted Book per Share is €4.45. Macrogenics' overall GF Score™ is 47/100 with 8 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted Book per Share calculated?
Cyclically Adjusted Book per Share is calculated from a company's financial statements. For Macrogenics (FRA:M55), the current Cyclically Adjusted Book per Share is €4.45 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Macrogenics (FRA:M55) Overvalued in 2026?

Based on GuruFocus' analysis, Macrogenics stock appears to be overvalued. The current stock price of €4.12 is trading 14.8% above its estimated GF Value™ of €3.59. GuruFocus considers Macrogenics to be Modestly Overvalued.

Key valuation signals for FRA:M55:

  • Cyclically Adjusted Book per Share: €4.45
  • GF Value™: €3.59 vs. price of €4.12 (14.8% above fair value)
  • GF Score™: 47/100 with 8 warning signs

No single metric tells the full story. See the FRA:M55 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Macrogenics Business Description

Other Exchanges MGNX:USA
Address 9704 Medical Center Drive, Rockville, MD, USA, 20850
Macrogenics Inc is a clinical-stage biopharmaceutical company focused on developing antibody-based therapeutics for the treatment of cancer. The company is currently developing therapeutics utilizing multiple modalities, including antibody-drug conjugates (ADCs) and multi-specific antibodies (which it refers to as DART and TRIDENT molecules). It is advancing three proprietary product candidates in clinical development: lorigerlimab, a bispecific DART molecule that targets checkpoint inhibitors PD-1 and CTLA-4; MGC026, an ADC that targets B7-H3 and delivers a novel topoisomerase I inhibitor (TOP1i)-based linker-payload, and MGC028, an ADC that targets ADAM9 and delivers a novel TOP1i-based linker-payload. Its segment is developing and commercializing monoclonal antibody-based therapeutics.
47GF Score

Get the complete analysis for FRA:M55

Cyclically Adjusted Book per Share is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€4.12
Price
€3.59
GF Value