uniQure NV (MEX:QUREN) Cyclically Adjusted Book per Share: MXN109.15 (As of Jun. 2026)

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MEX:QUREN uniQure NV MEX:QUREN
31 GF Score
Price MXN795.45
GF Value MXN131.10
Valuation Significantly Overvalued
! 4 Warning Signs
View Full Analysis

What is uniQure NV Cyclically Adjusted Book per Share?

uniQure NV MEX:QUREN 31 Cyclically Adjusted Book per Share is MXN109.15 as of Jun. 2026. GuruFocus rates MEX:QUREN with a GF Score™ of 31/100 and a GF Value™ of MXN131.10 (Significantly Overvalued). The stock has 4 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Book per Share and the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years.

uniQure NV's adjusted book value per share for the three months ended in Jun. 2026 was MXN81.551. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is MXN109.15 for the trailing ten years ended in Jun. 2026.

During the past 12 months, uniQure NV's average Cyclically Adjusted Book Growth Rate was -2.30% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the Cyclically Adjusted Book Growth Rate using Cyclically Adjusted Book per Share data.

As of today (2026-08-17), uniQure NV's current stock price is MXN795.45. uniQure NV's Cyclically Adjusted Book per Share for the quarter that ended in Jun. 2026 was MXN109.15. uniQure NV's Cyclically Adjusted PB Ratio of today is 7.29.

During the past 13 years, the highest Cyclically Adjusted PB Ratio of uniQure NV was 10.49. The lowest was 0.57. And the median was 2.47.


uniQure NV  (MEX:QUREN) Cyclically Adjusted Book per Share Explanation

If a company grows much fast than inflation, Cyclically Adjusted Book per Share may underestimate the company's equity. Cyclically Adjusted PB Ratio can seem to be too high even the actual PB Ratio is low.

For the Cyclically Adjusted PB Ratio, the book value of the past 10 years are inflation-adjusted and averaged. The result is used for P/B calculation. Since it looks at the average over the last 10 years, the Cyclically Adjusted PB Ratio is also called CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

uniQure NV's Cyclically Adjusted PB Ratio of today is calculated as

Cyclically Adjusted PB Ratio=Share Price/Cyclically Adjusted Book per Share
=795.45/109.15
=7.29

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

During the past 13 years, the highest Cyclically Adjusted PB Ratio of uniQure NV was 10.49. The lowest was 0.57. And the median was 2.47.


Be Aware

Cyclically Adjusted PB Ratio works better for cyclical companies. It gives you a better idea on the company's real book value.


uniQure NV Cyclically Adjusted Book per Share Related Terms


uniQure NV Cyclically Adjusted Book per Share Historical Data

* Premium members only.

The historical data trend for uniQure NV's Cyclically Adjusted Book per Share can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

uniQure NV Cyclically Adjusted Book per Share Chart

uniQure NV Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted Book per Share
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.00 113.99 98.66

uniQure NV Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Cyclically Adjusted Book per Share Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 141.56 117.76 98.66 154.51 109.15

MEX:QUREN vs ATAI, RARE, CLDX: Cyclically Adjusted Book per Share Comparison

For the Biotechnology subindustry, uniQure NV's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


uniQure NV Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, uniQure NV's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where uniQure NV's Cyclically Adjusted PB Ratio falls into.


MEX:QUREN
31GF Score
uniQure NV MEX:QUREN
Cyclically Adjusted Book per Share is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

uniQure NV Cyclically Adjusted Book per Share Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Book per Share and the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years.

What is Cyclically Adjusted Book per Share? How do we calculate Cyclically Adjusted Book per Share?

Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the Cyclically Adjusted Book per Share of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the book value per share from 2001 through 2010.

We adjusted the 2001 book value per share data with the total inflation from 2001 through 2010 to the equivalent book value in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart's book value is $1 a share in 2001, then the 2001's equivalent book value in 2010 is $1.4 a share. If Wal-Mart's book value is $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 book value in 2010 is $1.35. So on and so forth, you get the equivalent book value per share of past 10 years. Then you add them together and divided the sum by the count to get Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, uniQure NV's adjusted Book Value per Share data for the three months ended in Jun. 2026 was:

Adj_Book= Book Value per Share /CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=81.551/137.7700*137.7700
=81.551

Current CPI (Jun. 2026) = 137.7700.

uniQure NV Quarterly Data

Book Value per Share CPI Adj_Book
201609 62.463 100.570 85.568
201612 51.941 100.710 71.055
201703 33.796 101.440 45.900
201706 19.251 101.370 26.164
201709 13.880 102.030 18.742
201712 55.999 101.970 75.659
201803 57.332 102.470 77.082
201806 115.597 103.100 154.469
201809 100.288 103.950 132.917
201812 94.414 103.970 125.107
201903 80.703 105.370 105.518
201906 67.036 105.840 87.260
201909 158.541 106.700 204.707
201912 139.387 106.800 179.807
202003 156.221 106.850 201.428
202006 137.891 107.510 176.702
202009 113.163 107.880 144.517
202012 108.351 107.850 138.410
202103 101.789 108.870 128.809
202106 273.889 109.670 344.066
202109 262.879 110.790 326.896
202112 263.974 114.010 318.987
202203 233.087 119.460 268.813
202206 209.643 119.050 242.608
202209 180.964 126.890 196.480
202212 197.587 124.940 217.877
202303 156.481 124.720 172.854
202306 126.982 125.830 139.031
202309 97.928 127.160 106.099
202312 73.693 126.450 80.290
202403 50.226 128.580 53.816
202406 36.534 129.910 38.744
202409 22.551 131.610 23.606
202412 -2.875 131.630 -3.009
202503 12.599 133.330 13.019
202506 -1.374 133.960 -1.413
202509 67.499 135.920 68.418
202512 57.275 135.270 58.334
202603 42.725 136.910 42.993
202606 81.551 137.770 81.551

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

What does a Cyclically Adjusted Book per Share of MXN109.15 mean?
uniQure NV (MEX:QUREN) has a Cyclically Adjusted Book per Share of MXN109.15 as of Jun. 2026. Cyclically adjusted book value per share represents the company's inflation-adjusted book value per share over a 10-year period. View historical data on uniQure NV and its competitors.
Is uniQure NV's Cyclically Adjusted Book per Share too high?
uniQure NV's current Cyclically Adjusted Book per Share is MXN109.15. Overall, uniQure NV has a GF Score™ of 31/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does uniQure NV's Cyclically Adjusted Book per Share compare to ATAI and RARE?
uniQure NV's Cyclically Adjusted Book per Share of MXN109.15 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted Book per Share for a Biotechnology company?
A good Cyclically Adjusted Book per Share depends on the Biotechnology industry context. However, Cyclically Adjusted Book per Share should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted Book per Share mean?
A high Cyclically Adjusted Book per Share can signal that a stock is expensive relative to its fundamentals. Cyclically adjusted book value per share represents the company's inflation-adjusted book value per share over a 10-year period. View historical data on uniQure NV and its competitors. uniQure NV's current Cyclically Adjusted Book per Share is MXN109.15. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is uniQure NV stock overvalued right now?
Based on GuruFocus' analysis, uniQure NV (MEX:QUREN) is currently considered Significantly Overvalued. The stock's GF Value™ is MXN131.10, compared to a current price of MXN795.45 — trading 506.8% above its estimated fair value. The current Cyclically Adjusted Book per Share is MXN109.15. uniQure NV's overall GF Score™ is 31/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted Book per Share calculated?
Cyclically Adjusted Book per Share is calculated from a company's financial statements. For uniQure NV (MEX:QUREN), the current Cyclically Adjusted Book per Share is MXN109.15 as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is uniQure NV (MEX:QUREN) Overvalued in 2026?

Based on GuruFocus' analysis, uniQure NV stock appears to be overvalued. The current stock price of MXN795.45 is trading 506.8% above its estimated GF Value™ of MXN131.10. GuruFocus considers uniQure NV to be Significantly Overvalued.

Key valuation signals for MEX:QUREN:

  • Cyclically Adjusted Book per Share: MXN109.15
  • GF Value™: MXN131.10 vs. price of MXN795.45 (506.8% above fair value)
  • GF Score™: 31/100 with 4 warning signs

No single metric tells the full story. See the MEX:QUREN stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


uniQure NV Business Description

Other Exchanges QURE:USA0EE0:UKUQ1:Germany
Address Paasheuvelweg 25, Amsterdam, NH, NLD, 1105 BP
uniQure NV is a gene therapy company. It develops treatments and platforms for patients suffering from genetic and other devastating diseases. Its products and services are focused on hemophilia, Huntington's disease, and cardiovascular diseases. The company is focused on the development of the pipeline of gene therapies with the collaboration of Bristol Myers Squibb for cardiovascular diseases. Its program and pipeline involves: Huntington's Disease, Temporal Lobe Epilepsy (TLE), Fabry Disease, ALS (SOD1), Hemophilia B, Clinical Trials, and Research Programs.
31GF Score

Get the complete analysis for MEX:QUREN

Cyclically Adjusted Book per Share is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

MXN795.45
Price
MXN131.10
GF Value