uniQure NV (MEX:QUREN) E10: MXN-49.39 (As of Jun. 2026)

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MEX:QUREN uniQure NV MEX:QUREN
31 GF Score
Price MXN795.45
GF Value MXN130.91
Valuation Significantly Overvalued
! 4 Warning Signs
View Full Analysis

What is uniQure NV E10?

uniQure NV MEX:QUREN 31 E10 is MXN-49.39 as of Jun. 2026. GuruFocus rates MEX:QUREN with a GF Score™ of 31/100 and a GF Value™ of MXN130.91 (Significantly Overvalued). The stock has 4 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years.

uniQure NV's adjusted earnings per share data for the three months ended in Jun. 2026 was MXN-21.288. Add all the adjusted EPS for the past 10 years together and divide 10 will get our e10, which is MXN-49.39 for the trailing ten years ended in Jun. 2026.

During the past 3 years, the average E10 Growth Rate was -7.60% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the E10 growth rate using E10 data.

During the past 13 years, the highest 3-Year average E10 Growth Rate of uniQure NV was -7.60% per year. The lowest was -7.60% per year. And the median was -7.60% per year.

As of today (2026-08-16), uniQure NV's current stock price is MXN795.45. uniQure NV's E10 for the quarter that ended in Jun. 2026 was MXN-49.39. uniQure NV's Shiller PE Ratio of today is .


uniQure NV  (MEX:QUREN) E10 Explanation

If a company grows much fast than inflation, E10 may underestimate the company's earnings power. Shiller PE Ratio can seem to be too high even the actual P/E is low.

For the Shiller P/E, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller P/E is also called PE10.

The Shiller P/E was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.


Be Aware

Shiller PE Ratio works better for cyclical companies. It gives you a better idea on the company's real earnings power.


uniQure NV E10 Related Terms


uniQure NV E10 Historical Data

* Premium members only.

The historical data trend for uniQure NV's E10 can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

uniQure NV E10 Chart

uniQure NV Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
E10
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.00 -50.08 -44.33

uniQure NV Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
E10 Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -62.79 -52.76 -44.33 -69.41 -49.39

MEX:QUREN vs ATAI, RARE, CLDX: E10 Comparison

For the Biotechnology subindustry, uniQure NV's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


uniQure NV Shiller PE Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, uniQure NV's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where uniQure NV's Shiller PE Ratio falls into.


MEX:QUREN
31GF Score
uniQure NV MEX:QUREN
E10 is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

uniQure NV E10 Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. When we calculate the today's Shiller P/E ratio of a stock, we use today's price divided by E10.

What is E10? How do we calculate E10?

E10 is the average of the inflation adjusted earnings of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the E10 of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the earnings from 2001 through 2010.

We adjusted the earnings of 2001 earnings data with the total inflation from 2001 through 2010 to the equivalent earnings in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart earned $1 a share in 2001, then the 2001's equivalent earnings in 2010 is $1.4 a share. If Wal-Mart earns $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 earnings in 2010 is $1.35. So on and so forth, you get the equivalent earnings of past 10 years. Then you add them together and divided the sum by 10 to get E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, uniQure NV's adjusted earnings per share data for the three months ended in Jun. 2026 was:

Adj_EPS= Earnings per Share (Diluted) /CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=-21.288/137.7700*137.7700
=-21.288

Current CPI (Jun. 2026) = 137.7700.

uniQure NV Quarterly Data

per share eps CPI Adj_EPS
201609 -11.795 100.570 -16.158
201612 -11.958 100.710 -16.358
201703 -15.063 101.440 -20.458
201706 -15.003 101.370 -20.390
201709 -7.259 102.030 -9.802
201712 -17.872 101.970 -24.147
201803 -10.719 102.470 -14.412
201806 -11.200 103.100 -14.966
201809 -11.036 103.950 -14.627
201812 -11.585 103.970 -15.351
201903 -14.355 105.370 -18.769
201906 -15.943 105.840 -20.753
201909 -11.450 106.700 -14.784
201912 -18.294 106.800 -23.599
202003 -14.772 106.850 -19.047
202006 -22.159 107.510 -28.396
202009 -26.730 107.880 -34.136
202012 -0.199 107.850 -0.254
202103 -18.601 108.870 -23.539
202106 169.400 109.670 212.804
202109 -16.244 110.790 -20.200
202112 3.487 114.010 4.214
202203 -19.911 119.460 -22.963
202206 -16.899 119.050 -19.556
202209 -20.517 126.890 -22.276
202212 2.924 124.940 3.224
202303 -29.381 124.720 -32.455
202306 -24.687 125.830 -27.030
202309 -32.748 127.160 -35.480
202312 -25.971 126.450 -28.296
202403 -22.571 128.580 -24.184
202406 -21.251 129.910 -22.537
202409 -17.918 131.610 -18.757
202412 -31.284 131.630 -32.743
202503 -16.776 133.330 -17.335
202506 -12.992 133.960 -13.362
202509 -25.315 135.920 -25.660
202512 -10.083 135.270 -10.269
202603 -15.328 136.910 -15.424
202606 -21.288 137.770 -21.288

Add all the adjusted EPS together and divide 10 will get our e10.

Frequently Asked Questions Learn more about E10 →
What does a E10 of MXN-49.39 mean?
uniQure NV (MEX:QUREN) has a E10 of MXN-49.39 as of Jun. 2026. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on uniQure NV and its competitors.
Is uniQure NV's E10 too high?
uniQure NV's current E10 is MXN-49.39. Overall, uniQure NV has a GF Score™ of 31/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does uniQure NV's E10 compare to ATAI and RARE?
uniQure NV's E10 of MXN-49.39 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good E10 for a Biotechnology company?
A good E10 depends on the Biotechnology industry context. However, E10 should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high E10 mean?
A high E10 can signal that a stock is expensive relative to its fundamentals. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on uniQure NV and its competitors. uniQure NV's current E10 is MXN-49.39. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is uniQure NV stock overvalued right now?
Based on GuruFocus' analysis, uniQure NV (MEX:QUREN) is currently considered Significantly Overvalued. The stock's GF Value™ is MXN130.91, compared to a current price of MXN795.45 — trading 507.6% above its estimated fair value. The current E10 is MXN-49.39. uniQure NV's overall GF Score™ is 31/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is E10 calculated?
E10 is calculated from a company's financial statements. For uniQure NV (MEX:QUREN), the current E10 is MXN-49.39 as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is uniQure NV (MEX:QUREN) Overvalued in 2026?

Based on GuruFocus' analysis, uniQure NV stock appears to be overvalued. The current stock price of MXN795.45 is trading 507.6% above its estimated GF Value™ of MXN130.91. GuruFocus considers uniQure NV to be Significantly Overvalued.

Key valuation signals for MEX:QUREN:

  • E10: MXN-49.39
  • GF Value™: MXN130.91 vs. price of MXN795.45 (507.6% above fair value)
  • GF Score™: 31/100 with 4 warning signs

No single metric tells the full story. See the MEX:QUREN stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


uniQure NV Business Description

Other Exchanges QURE:USA0EE0:UKUQ1:Germany
Address Paasheuvelweg 25, Amsterdam, NH, NLD, 1105 BP
uniQure NV is a gene therapy company. It develops treatments and platforms for patients suffering from genetic and other devastating diseases. Its products and services are focused on hemophilia, Huntington's disease, and cardiovascular diseases. The company is focused on the development of the pipeline of gene therapies with the collaboration of Bristol Myers Squibb for cardiovascular diseases. Its program and pipeline involves: Huntington's Disease, Temporal Lobe Epilepsy (TLE), Fabry Disease, ALS (SOD1), Hemophilia B, Clinical Trials, and Research Programs.
31GF Score

Get the complete analysis for MEX:QUREN

E10 is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

MXN795.45
Price
MXN130.91
GF Value