RGEN (Repligen) Cyclically Adjusted Book per Share: $29.46 (As of Jun. 2026)

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

RGEN Repligen Corp RGEN
88 GF Score
Price $165.05
GF Value $178.63
Valuation Fairly Valued
! 7 Warning Signs
View Full Analysis

What is Repligen Cyclically Adjusted Book per Share?

Repligen RGEN -2.03% 88 Cyclically Adjusted Book per Share is $29.46 as of Jun. 2026. GuruFocus rates RGEN with a GF Score™ of 88/100 and a GF Value™ of $178.63 (Fairly Valued). The stock has 7 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Book per Share and the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years.

Repligen's adjusted book value per share for the three months ended in Jun. 2026 was $37.429. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is $29.46 for the trailing ten years ended in Jun. 2026.

During the past 12 months, Repligen's average Cyclically Adjusted Book Growth Rate was 16.30% per year. During the past 3 years, the average Cyclically Adjusted Book Growth Rate was 19.40% per year. During the past 5 years, the average Cyclically Adjusted Book Growth Rate was 25.10% per year. During the past 10 years, the average Cyclically Adjusted Book Growth Rate was 29.20% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the Cyclically Adjusted Book Growth Rate using Cyclically Adjusted Book per Share data.

During the past 13 years, the highest 3-Year average Cyclically Adjusted Book Growth Rate of Repligen was 35.10% per year. The lowest was -23.60% per year. And the median was 12.45% per year.

As of today (2026-09-10), Repligen's current stock price is $165.05. Repligen's Cyclically Adjusted Book per Share for the quarter that ended in Jun. 2026 was $29.46. Repligen's Cyclically Adjusted PB Ratio of today is 5.60.

During the past 13 years, the highest Cyclically Adjusted PB Ratio of Repligen was 31.08. The lowest was 3.62. And the median was 11.27.


Repligen  (NAS:RGEN) Cyclically Adjusted Book per Share Explanation

If a company grows much fast than inflation, Cyclically Adjusted Book per Share may underestimate the company's equity. Cyclically Adjusted PB Ratio can seem to be too high even the actual PB Ratio is low.

For the Cyclically Adjusted PB Ratio, the book value of the past 10 years are inflation-adjusted and averaged. The result is used for P/B calculation. Since it looks at the average over the last 10 years, the Cyclically Adjusted PB Ratio is also called CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Repligen's Cyclically Adjusted PB Ratio of today is calculated as

Cyclically Adjusted PB Ratio=Share Price/Cyclically Adjusted Book per Share
=165.05/29.46
=5.60

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

During the past 13 years, the highest Cyclically Adjusted PB Ratio of Repligen was 31.08. The lowest was 3.62. And the median was 11.27.


Be Aware

Cyclically Adjusted PB Ratio works better for cyclical companies. It gives you a better idea on the company's real book value.


Repligen Cyclically Adjusted Book per Share Related Terms


Repligen Cyclically Adjusted Book per Share Historical Data

* Premium members only.

The historical data trend for Repligen's Cyclically Adjusted Book per Share can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Repligen Cyclically Adjusted Book per Share Chart

Repligen Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted Book per Share
Get a 7-Day Free Trial Premium Member Only Premium Member Only 12.11 15.91 19.59 23.26 27.06

Repligen Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Cyclically Adjusted Book per Share Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 25.34 26.32 27.06 28.38 29.46

RGEN vs AVTR, ALGN, ATR: Cyclically Adjusted Book per Share Comparison

For the Medical Instruments & Supplies subindustry, Repligen's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Repligen Cyclically Adjusted PB Ratio vs Medical Devices & Instruments Industry

For the Medical Devices & Instruments industry and Healthcare sector, Repligen's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Repligen's Cyclically Adjusted PB Ratio falls into.


RGEN
88GF Score
Repligen Corp RGEN
Cyclically Adjusted Book per Share is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Repligen Cyclically Adjusted Book per Share Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Book per Share and the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years.

What is Cyclically Adjusted Book per Share? How do we calculate Cyclically Adjusted Book per Share?

Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the Cyclically Adjusted Book per Share of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the book value per share from 2001 through 2010.

We adjusted the 2001 book value per share data with the total inflation from 2001 through 2010 to the equivalent book value in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart's book value is $1 a share in 2001, then the 2001's equivalent book value in 2010 is $1.4 a share. If Wal-Mart's book value is $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 book value in 2010 is $1.35. So on and so forth, you get the equivalent book value per share of past 10 years. Then you add them together and divided the sum by the count to get Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, Repligen's adjusted Book Value per Share data for the three months ended in Jun. 2026 was:

Adj_Book= Book Value per Share /CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=37.429/333.9520*333.9520
=37.429

Current CPI (Jun. 2026) = 333.9520.

Repligen Quarterly Data

Book Value per Share CPI Adj_Book
201609 4.922 241.428 6.808
201612 4.987 241.432 6.898
201703 5.188 243.801 7.106
201706 5.596 244.955 7.629
201709 13.243 246.819 17.918
201712 13.572 246.524 18.385
201803 13.668 249.554 18.290
201806 13.668 251.989 18.114
201809 13.830 252.439 18.296
201812 14.017 251.233 18.632
201903 14.181 254.202 18.630
201906 18.279 256.143 23.832
201909 20.078 256.759 26.114
201912 20.350 256.974 26.446
202003 20.463 258.115 26.475
202006 20.955 257.797 27.145
202009 21.383 260.280 27.435
202012 27.924 260.474 35.801
202103 28.347 264.877 35.739
202106 29.163 271.696 35.845
202109 31.026 274.310 37.772
202112 31.635 278.802 37.893
202203 31.868 287.504 37.016
202206 32.549 296.311 36.684
202209 33.053 296.808 37.189
202212 34.391 296.797 38.696
202303 34.873 301.836 38.584
202306 35.356 305.109 38.698
202309 35.653 307.789 38.684
202312 35.234 306.746 38.359
202403 35.290 312.332 37.733
202406 35.532 314.175 37.769
202409 35.995 315.301 38.124
202412 35.169 315.605 37.213
202503 35.342 319.799 36.906
202506 36.651 322.561 37.945
202509 37.011 324.800 38.054
202512 37.392 324.054 38.534
202603 37.332 330.213 37.755
202606 37.429 333.952 37.429

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

What does a Cyclically Adjusted Book per Share of $29.46 mean?
Repligen (RGEN) has a Cyclically Adjusted Book per Share of $29.46 as of Jun. 2026. Cyclically adjusted book value per share represents the company's inflation-adjusted book value per share over a 10-year period. View historical data on Repligen and its competitors.
Is Repligen's Cyclically Adjusted Book per Share too high?
Repligen's current Cyclically Adjusted Book per Share is $29.46. Overall, Repligen has a GF Score™ of 88/100 and is considered Fairly Valued, reflecting its overall financial health beyond just this single metric.
How does Repligen's Cyclically Adjusted Book per Share compare to AVTR and ALGN?
Repligen's Cyclically Adjusted Book per Share of $29.46 can be compared against companies in the Medical Devices & Instruments industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted Book per Share for a Medical Devices & Instruments company?
A good Cyclically Adjusted Book per Share depends on the Medical Devices & Instruments industry context. However, Cyclically Adjusted Book per Share should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted Book per Share mean?
A high Cyclically Adjusted Book per Share can signal that a stock is expensive relative to its fundamentals. Cyclically adjusted book value per share represents the company's inflation-adjusted book value per share over a 10-year period. View historical data on Repligen and its competitors. Repligen's current Cyclically Adjusted Book per Share is $29.46. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Repligen stock overvalued right now?
Based on GuruFocus' analysis, Repligen (RGEN) is currently considered Fairly Valued. The stock's GF Value™ is $178.63, compared to a current price of $165.05 — trading 7.6% below its estimated fair value. The current Cyclically Adjusted Book per Share is $29.46. Repligen's overall GF Score™ is 88/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted Book per Share calculated?
Cyclically Adjusted Book per Share is calculated from a company's financial statements. For Repligen (RGEN), the current Cyclically Adjusted Book per Share is $29.46 as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Repligen (RGEN) Overvalued in 2026?

Based on GuruFocus' analysis, Repligen stock appears to be undervalued. The current stock price of $165.05 is trading 7.6% below its estimated GF Value™ of $178.63. GuruFocus considers Repligen to be Fairly Valued.

Key valuation signals for RGEN:

  • Cyclically Adjusted Book per Share: $29.46
  • GF Value™: $178.63 vs. price of $165.05 (7.6% below fair value)
  • GF Score™: 88/100 with 7 warning signs

No single metric tells the full story. See the RGEN stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Repligen Business Description

Other Exchanges RGN:Germany
Address 41 Seyon Street, Building 1, Suite 100, Waltham, MA, USA, 02453
Repligen, headquartered in Waltham, Massachusetts, is a global life sciences company that develops and sells bioprocessing equipment and supplies used in the manufacturing of biologic drugs, including monoclonal antibodies, recombinant proteins, vaccines, and cell and gene therapies. Its customers include biopharmaceutical companies, contract development and manufacturing organizations, or CDMOs, and other life science companies. It sells four main product categories: filtration (including fluid management) is the largest category (about 55% of total revenue), while chromatography, proteins, and process analytics are 21%, 11%, and 13%, respectively. Customers in North America, Europe, and Asia Pacific contribute about 44%, 37%, and 19% of revenue, respectively.
88GF Score

Get the complete analysis for RGEN

Cyclically Adjusted Book per Share is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$165.05
Price
$178.63
GF Value