RGEN (Repligen) E10: $1.13 (As of Jun. 2026)

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Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
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Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

RGEN Repligen Corp RGEN
88 GF Score
Price $163.92
GF Value $177.30
Valuation Fairly Valued
! 7 Warning Signs
View Full Analysis

What is Repligen E10?

Repligen RGEN +2.80% 88 E10 is $1.13 as of Jun. 2026. GuruFocus rates RGEN with a GF Score™ of 88/100 and a GF Value™ of $177.30 (Fairly Valued). The stock has 7 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years.

Repligen's adjusted earnings per share data for the three months ended in Jun. 2026 was $0.090. Add all the adjusted EPS for the past 10 years together and divide 10 will get our e10, which is $1.13 for the trailing ten years ended in Jun. 2026.

During the past 12 months, Repligen's average E10 Growth Rate was 7.60% per year. During the past 3 years, the average E10 Growth Rate was 1.30% per year. During the past 5 years, the average E10 Growth Rate was 16.10% per year. During the past 10 years, the average E10 Growth Rate was 17.70% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the E10 growth rate using E10 data.

During the past 13 years, the highest 3-Year average E10 Growth Rate of Repligen was 180.20% per year. The lowest was -3.30% per year. And the median was 17.80% per year.

As of today (2026-08-08), Repligen's current stock price is $163.92. Repligen's E10 for the quarter that ended in Jun. 2026 was $1.13. Repligen's Shiller PE Ratio of today is 145.06.

During the past 13 years, the highest Shiller PE Ratio of Repligen was 538.77. The lowest was 79.62. And the median was 161.32.


Repligen  (NAS:RGEN) E10 Explanation

If a company grows much fast than inflation, E10 may underestimate the company's earnings power. Shiller PE Ratio can seem to be too high even the actual P/E is low.

For the Shiller P/E, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller P/E is also called PE10.

The Shiller P/E was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.

Repligen's Shiller P/E Ratio of today is calculated as

Shiller PE Ratio=Share Price/E10
=163.92/1.13
=145.06

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

During the past 13 years, the highest Shiller P/E Ratio of Repligen was 538.77. The lowest was 79.62. And the median was 161.32.


Be Aware

Shiller PE Ratio works better for cyclical companies. It gives you a better idea on the company's real earnings power.


Repligen E10 Related Terms


Repligen E10 Historical Data

* Premium members only.

The historical data trend for Repligen's E10 can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Repligen E10 Chart

Repligen Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
E10
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.73 1.05 1.07 1.02 1.09

Repligen Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
E10 Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 1.05 1.07 1.09 1.12 1.13

RGEN vs AVTR, ATR, TFX: E10 Comparison

For the Medical Instruments & Supplies subindustry, Repligen's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Repligen Shiller PE Ratio vs Medical Devices & Instruments Industry

For the Medical Devices & Instruments industry and Healthcare sector, Repligen's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where Repligen's Shiller PE Ratio falls into.


RGEN
88GF Score
Repligen Corp RGEN
E10 is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Repligen E10 Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. When we calculate the today's Shiller P/E ratio of a stock, we use today's price divided by E10.

What is E10? How do we calculate E10?

E10 is the average of the inflation adjusted earnings of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the E10 of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the earnings from 2001 through 2010.

We adjusted the earnings of 2001 earnings data with the total inflation from 2001 through 2010 to the equivalent earnings in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart earned $1 a share in 2001, then the 2001's equivalent earnings in 2010 is $1.4 a share. If Wal-Mart earns $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 earnings in 2010 is $1.35. So on and so forth, you get the equivalent earnings of past 10 years. Then you add them together and divided the sum by 10 to get E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, Repligen's adjusted earnings per share data for the three months ended in Jun. 2026 was:

Adj_EPS= Earnings per Share (Diluted) /CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=0.09/333.9520*333.9520
=0.090

Current CPI (Jun. 2026) = 333.9520.

Repligen Quarterly Data

per share eps CPI Adj_EPS
201609 0.030 241.428 0.041
201612 0.150 241.432 0.207
201703 0.090 243.801 0.123
201706 0.240 244.955 0.327
201709 0.110 246.819 0.149
201712 0.270 246.524 0.366
201803 0.080 249.554 0.107
201806 0.060 251.989 0.080
201809 0.100 252.439 0.132
201812 0.120 251.233 0.160
201903 0.170 254.202 0.223
201906 0.170 256.143 0.222
201909 0.030 256.759 0.039
201912 0.070 256.974 0.091
202003 0.180 258.115 0.233
202006 0.300 257.797 0.389
202009 0.270 260.280 0.346
202012 0.360 260.474 0.462
202103 0.520 264.877 0.656
202106 0.640 271.696 0.787
202109 0.580 274.310 0.706
202112 0.500 278.802 0.599
202203 0.810 287.504 0.941
202206 0.880 296.311 0.992
202209 0.710 296.808 0.799
202212 0.850 296.797 0.956
202303 0.270 301.836 0.299
202306 0.350 305.109 0.383
202309 0.300 307.789 0.326
202312 -0.460 306.746 -0.501
202403 0.060 312.332 0.064
202406 0.100 314.175 0.106
202409 -0.010 315.301 -0.011
202412 -0.600 315.605 -0.635
202503 0.100 319.799 0.104
202506 0.260 322.561 0.269
202509 0.260 324.800 0.267
202512 0.230 324.054 0.237
202603 0.150 330.213 0.152
202606 0.090 333.952 0.090

Add all the adjusted EPS together and divide 10 will get our e10.

Frequently Asked Questions Learn more about E10 →
What does a E10 of $1.13 mean?
Repligen (RGEN) has a E10 of $1.13 as of Jun. 2026. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Repligen and its competitors.
Is Repligen's E10 too high?
Repligen's current E10 is $1.13. Overall, Repligen has a GF Score™ of 88/100 and is considered Fairly Valued, reflecting its overall financial health beyond just this single metric.
How does Repligen's E10 compare to AVTR and ATR?
Repligen's E10 of $1.13 can be compared against companies in the Medical Devices & Instruments industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good E10 for a Medical Devices & Instruments company?
A good E10 depends on the Medical Devices & Instruments industry context. However, E10 should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high E10 mean?
A high E10 can signal that a stock is expensive relative to its fundamentals. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Repligen and its competitors. Repligen's current E10 is $1.13. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Repligen stock overvalued right now?
Based on GuruFocus' analysis, Repligen (RGEN) is currently considered Fairly Valued. The stock's GF Value™ is $177.30, compared to a current price of $163.92 — trading 7.5% below its estimated fair value. The current E10 is $1.13. Repligen's overall GF Score™ is 88/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is E10 calculated?
E10 is calculated from a company's financial statements. For Repligen (RGEN), the current E10 is $1.13 as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Repligen (RGEN) Overvalued in 2026?

Based on GuruFocus' analysis, Repligen stock appears to be undervalued. The current stock price of $163.92 is trading 7.5% below its estimated GF Value™ of $177.30. GuruFocus considers Repligen to be Fairly Valued.

Key valuation signals for RGEN:

  • E10: $1.13
  • GF Value™: $177.30 vs. price of $163.92 (7.5% below fair value)
  • GF Score™: 88/100 with 7 warning signs

No single metric tells the full story. See the RGEN stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Repligen Business Description

Other Exchanges RGN:Germany
Address 41 Seyon Street, Building 1, Suite 100, Waltham, MA, USA, 02453
Repligen, headquartered in Waltham, Massachusetts, is a global life sciences company that develops and sells bioprocessing equipment and supplies used in the manufacturing of biologic drugs, including monoclonal antibodies, recombinant proteins, vaccines, and cell and gene therapies. Its customers include biopharmaceutical companies, contract development and manufacturing organizations, or CDMOs, and other life science companies. It sells four main product categories: filtration (including fluid management) is the largest category (about 55% of total revenue), while chromatography, proteins, and process analytics are 21%, 11%, and 13%, respectively. Customers in North America, Europe, and Asia Pacific contribute about 44%, 37%, and 19% of revenue, respectively.
88GF Score

Get the complete analysis for RGEN

E10 is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$163.92
Price
$177.30
GF Value