XRTX (XORTX Therapeutics) Cyclically Adjusted Book per Share: $9.84 (As of Jun. 2026)

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XRTX XORTX Therapeutics Inc XRTX
32 GF Score
Price $2.40
! 1 Warning Sign
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What is XORTX Therapeutics Cyclically Adjusted Book per Share?

XORTX Therapeutics XRTX +7.44% 32 Cyclically Adjusted Book per Share is $9.84 as of Jun. 2026. GuruFocus rates XRTX with a GF Score™ of 32/100. The stock has 1 warning sign investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Book per Share and the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years.

XORTX Therapeutics's adjusted book value per share for the three months ended in Jun. 2026 was $3.180. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is $9.84 for the trailing ten years ended in Jun. 2026.

During the past 12 months, XORTX Therapeutics's average Cyclically Adjusted Book Growth Rate was -0.70% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the Cyclically Adjusted Book Growth Rate using Cyclically Adjusted Book per Share data.

As of today (2026-09-07), XORTX Therapeutics's current stock price is $2.4016. XORTX Therapeutics's Cyclically Adjusted Book per Share for the quarter that ended in Jun. 2026 was $9.84. XORTX Therapeutics's Cyclically Adjusted PB Ratio of today is 0.24.

During the past 11 years, the highest Cyclically Adjusted PB Ratio of XORTX Therapeutics was 0.24. The lowest was 0.00. And the median was 0.00.


XORTX Therapeutics  (NAS:XRTX) Cyclically Adjusted Book per Share Explanation

If a company grows much fast than inflation, Cyclically Adjusted Book per Share may underestimate the company's equity. Cyclically Adjusted PB Ratio can seem to be too high even the actual PB Ratio is low.

For the Cyclically Adjusted PB Ratio, the book value of the past 10 years are inflation-adjusted and averaged. The result is used for P/B calculation. Since it looks at the average over the last 10 years, the Cyclically Adjusted PB Ratio is also called CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

XORTX Therapeutics's Cyclically Adjusted PB Ratio of today is calculated as

Cyclically Adjusted PB Ratio=Share Price/Cyclically Adjusted Book per Share
=2.4016/9.84
=0.24

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

During the past 11 years, the highest Cyclically Adjusted PB Ratio of XORTX Therapeutics was 0.24. The lowest was 0.00. And the median was 0.00.


Be Aware

Cyclically Adjusted PB Ratio works better for cyclical companies. It gives you a better idea on the company's real book value.


XORTX Therapeutics Cyclically Adjusted Book per Share Related Terms


XORTX Therapeutics Cyclically Adjusted Book per Share Historical Data

* Premium members only.

The historical data trend for XORTX Therapeutics's Cyclically Adjusted Book per Share can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

XORTX Therapeutics Cyclically Adjusted Book per Share Chart

XORTX Therapeutics Annual Data
Trend Feb16 Feb17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted Book per Share
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.00 10.02 9.95

XORTX Therapeutics Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Cyclically Adjusted Book per Share Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 10.16 10.18 9.95 9.88 9.84

XRTX vs VRTX, REGN, MRNA: Cyclically Adjusted Book per Share Comparison

For the Biotechnology subindustry, XORTX Therapeutics's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


XORTX Therapeutics Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, XORTX Therapeutics's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where XORTX Therapeutics's Cyclically Adjusted PB Ratio falls into.


XRTX
32GF Score
XORTX Therapeutics Inc XRTX
Cyclically Adjusted Book per Share is just one metric. See GF Score™, valuation, warning signs, and more.
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XORTX Therapeutics Cyclically Adjusted Book per Share Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Book per Share and the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years.

What is Cyclically Adjusted Book per Share? How do we calculate Cyclically Adjusted Book per Share?

Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the Cyclically Adjusted Book per Share of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the book value per share from 2001 through 2010.

We adjusted the 2001 book value per share data with the total inflation from 2001 through 2010 to the equivalent book value in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart's book value is $1 a share in 2001, then the 2001's equivalent book value in 2010 is $1.4 a share. If Wal-Mart's book value is $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 book value in 2010 is $1.35. So on and so forth, you get the equivalent book value per share of past 10 years. Then you add them together and divided the sum by the count to get Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, XORTX Therapeutics's adjusted Book Value per Share data for the three months ended in Jun. 2026 was:

Adj_Book= Book Value per Share /CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=3.18/133.5265*133.5265
=3.180

Current CPI (Jun. 2026) = 133.5265.

XORTX Therapeutics Quarterly Data

Book Value per Share CPI Adj_Book
201608 4.852 101.686 6.371
201611 8.763 101.607 11.516
201702 3.526 102.476 4.594
201705 2.526 103.108 3.271
201708 1.289 103.108 1.669
201711 0.846 103.740 1.089
201803 6.496 105.004 8.261
201806 4.782 105.557 6.049
201809 2.992 105.636 3.782
201812 1.983 105.399 2.512
201903 1.025 106.979 1.279
201906 0.134 107.690 0.166
201909 -0.639 107.611 -0.793
201912 -1.361 107.769 -1.686
202003 10.019 107.927 12.395
202006 9.532 108.401 11.741
202009 8.104 108.164 10.004
202012 6.396 108.559 7.867
202103 13.221 110.298 16.005
202106 12.875 111.720 15.388
202109 -15.675 112.905 -18.538
202112 45.685 113.774 53.616
202203 37.142 117.646 42.156
202206 32.879 120.806 36.341
202209 27.090 120.648 29.982
202212 20.949 120.964 23.125
202303 22.648 122.702 24.646
202306 18.495 124.203 19.883
202309 15.215 125.230 16.223
202312 11.605 125.072 12.389
202403 4.287 126.258 4.534
202406 4.656 127.522 4.875
202409 3.673 127.285 3.853
202412 4.795 127.364 5.027
202503 3.616 129.181 3.738
202506 2.679 129.892 2.754
202509 1.894 130.287 1.941
202512 1.497 130.366 1.533
202603 0.922 132.262 0.931
202606 3.180 133.527 3.180

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

What does a Cyclically Adjusted Book per Share of $9.84 mean?
XORTX Therapeutics (XRTX) has a Cyclically Adjusted Book per Share of $9.84 as of Jun. 2026. Cyclically adjusted book value per share represents the company's inflation-adjusted book value per share over a 10-year period. View historical data on XORTX Therapeutics and its competitors.
Is XORTX Therapeutics' Cyclically Adjusted Book per Share too high?
XORTX Therapeutics' current Cyclically Adjusted Book per Share is $9.84. Overall, XORTX Therapeutics has a GF Score™ of 32/100, reflecting its overall financial health beyond just this single metric.
How does XORTX Therapeutics' Cyclically Adjusted Book per Share compare to VRTX and REGN?
XORTX Therapeutics' Cyclically Adjusted Book per Share of $9.84 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted Book per Share for a Biotechnology company?
A good Cyclically Adjusted Book per Share depends on the Biotechnology industry context. However, Cyclically Adjusted Book per Share should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted Book per Share mean?
A high Cyclically Adjusted Book per Share can signal that a stock is expensive relative to its fundamentals. Cyclically adjusted book value per share represents the company's inflation-adjusted book value per share over a 10-year period. View historical data on XORTX Therapeutics and its competitors. XORTX Therapeutics's current Cyclically Adjusted Book per Share is $9.84. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is XORTX Therapeutics stock overvalued right now?
XORTX Therapeutics (XRTX) has a current Cyclically Adjusted Book per Share of $9.84. The current Cyclically Adjusted Book per Share is $9.84. XORTX Therapeutics' overall GF Score™ is 32/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted Book per Share calculated?
Cyclically Adjusted Book per Share is calculated from a company's financial statements. For XORTX Therapeutics (XRTX), the current Cyclically Adjusted Book per Share is $9.84 as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

XORTX Therapeutics Business Description

Other Exchanges ANU:GermanyXRTX:Canada
Address 3710 - 33rd Street NW, Calgary, AB, CAN, T2L 2M1
XORTX Therapeutics Inc is a clinical-stage pharmaceutical company focused on developing therapies to treat gout and progressive kidney disease modulated by aberrant purine and uric acid metabolism in orphan disease indications such as allopurinol-intolerant gout and autosomal dominant polycystic kidney disease, as well as more prevalent type 2 diabetic nephropathy and fatty liver disease. Its focus is on developing products to slow and/or reverse the progression of these diseases. The Company operates in one reportable operating segment: the development and commercialization of therapies to treat hyperuricemia-related diseases.
32GF Score

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Cyclically Adjusted Book per Share is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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