XRTX (XORTX Therapeutics) Profitability Rank: 1 (As of Jun. 2026) — Near Median

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XRTX XORTX Therapeutics Inc XRTX
32 GF Score
Price $2.40
! 1 Warning Sign
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What is XORTX Therapeutics Profitability Rank?

XORTX Therapeutics XRTX +7.44% 32 Profitability Rank is 1 as of Jun. 2026, which is at its 10-year median of 1.00. GuruFocus rates XRTX with a GF Score™ of 32/100. The stock has 1 warning sign investors should review.

XORTX Therapeutics has the Profitability Rank of 1. It has had trouble to make a profit.

GuruFocus Profitability Rank ranks how profitable a company is and how likely the company's business will stay that way. It is rated on a scale of 1 to 10 and is based on these factors:

1. Operating Margin %
2. Piotroski F-Score
3. Trend of the Operating Margin % (5-year average). The company with an uptrend profit margin has a higher rank.
4. Consistency of the profitability
5. Predictability Rank

A higher score indicates superior profitability, with companies rated 7 or above considered to have more robust and sustainable profit generation. Conversely, a score of 3 or lower suggests challenges in generating consistent profits.

XORTX Therapeutics's Operating Margin % for the quarter that ended in Jun. 2026 was %. As of today, XORTX Therapeutics's Piotroski F-Score is 2.


XORTX Therapeutics Profitability Rank Related Terms


XRTX vs VRTX, REGN, MRNA: Profitability Rank Comparison

For the Biotechnology subindustry, XORTX Therapeutics's Profitability Rank, along with its competitors' market caps and Profitability Rank data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


XORTX Therapeutics Profitability Rank vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, XORTX Therapeutics's Profitability Rank distribution charts can be found below:

* The bar in red indicates where XORTX Therapeutics's Profitability Rank falls into.


XRTX
32GF Score
XORTX Therapeutics Inc XRTX
Profitability Rank is just one metric. See GF Score™, valuation, warning signs, and more.
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XORTX Therapeutics Profitability Rank Calculation

GuruFocus Profitability Rank ranks how profitable a company is and how likely the company's business will stay that way.

The rank is rated on a scale of 1 to 10. A higher score indicates superior profitability, with companies rated 7 or above considered to have more robust and sustainable profit generation. Conversely, a score of 3 or lower suggests challenges in generating consistent profits.

XORTX Therapeutics has the Profitability Rank of 1. It has had trouble to make a profit.

Profitability Rank is not directly related to the Financial Strength. But if a company is consistently profitable, its financial strength will be stronger.

Profitability Rank is based on these factors:

1. Operating Margin %

Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.

XORTX Therapeutics's Operating Margin % for the quarter that ended in Jun. 2026 is calculated as:

Operating Margin %=Operating Income (Q: Jun. 2026 ) / Revenue (Q: Jun. 2026 )
=-1.691 / 0
= %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

2. Piotroski F-Score

Warning Sign:

Piotroski F-Score of 2 is low, which usually implies poor business operation.

The zones of discrimination were as such:

Good or high score = 8 or 9
Bad or low score = 0 or 1

XORTX Therapeutics has an F-score of 2. It is a bad or low score, which usually implies poor business operation.

3. Trend of the Operating Margin % (5-year average). The company with an uptrend profit margin has a higher rank.

4. Consistency of the profitability

5. Predictability Rank

Frequently Asked Questions Learn more about Profitability Rank →
What does a Profitability Rank of 1 mean?
XORTX Therapeutics (XRTX) has a Profitability Rank of 1 as of Jun. 2026. Profitability and Growth ranks a company based on its profit margins and earnings growth. View historical data on XORTX Therapeutics and its competitors. This is near median its historical median of 1.00. Over the past decade, XORTX Therapeutics' Profitability Rank has ranged from 1.00 to 2.00.
Is XORTX Therapeutics' Profitability Rank too high?
XORTX Therapeutics' current Profitability Rank of 1 is near median its 10-year median of 1.00. Over the past 10 years, this metric has ranged from a low of 1.00 to a high of 2.00. Overall, XORTX Therapeutics has a GF Score™ of 32/100, reflecting its overall financial health beyond just this single metric.
How does XORTX Therapeutics' Profitability Rank compare to VRTX and REGN?
XORTX Therapeutics' Profitability Rank of 1 can be compared against companies in the Biotechnology industry. Historically, XORTX Therapeutics' own Profitability Rank has ranged from 1.00 to 2.00 over the past decade. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Profitability Rank for a Biotechnology company?
A good Profitability Rank depends on the Biotechnology industry context. However, Profitability Rank should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Profitability Rank mean?
A high Profitability Rank can signal that a stock is expensive relative to its fundamentals. Profitability and Growth ranks a company based on its profit margins and earnings growth. View historical data on XORTX Therapeutics and its competitors. XORTX Therapeutics's current Profitability Rank is 1, which is near median its own 10-year median of 1.00. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is XORTX Therapeutics stock overvalued right now?
XORTX Therapeutics (XRTX) has a current Profitability Rank of 1. The current Profitability Rank is 1, which is near median its 10-year median of 1.00. XORTX Therapeutics' overall GF Score™ is 32/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Profitability Rank calculated?
Profitability Rank is calculated from a company's financial statements. For XORTX Therapeutics (XRTX), the current Profitability Rank is 1 as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

XORTX Therapeutics Business Description

Other Exchanges ANU:GermanyXRTX:Canada
Address 3710 - 33rd Street NW, Calgary, AB, CAN, T2L 2M1
XORTX Therapeutics Inc is a clinical-stage pharmaceutical company focused on developing therapies to treat gout and progressive kidney disease modulated by aberrant purine and uric acid metabolism in orphan disease indications such as allopurinol-intolerant gout and autosomal dominant polycystic kidney disease, as well as more prevalent type 2 diabetic nephropathy and fatty liver disease. Its focus is on developing products to slow and/or reverse the progression of these diseases. The Company operates in one reportable operating segment: the development and commercialization of therapies to treat hyperuricemia-related diseases.
32GF Score

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Profitability Rank is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$2.40
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