OPKO Health (MEX:OPK) Cyclically Adjusted FCF per Share: MXN-3.32 (As of Mar. 2026)


MEX:OPK OPKO Health Inc MEX:OPK
53 GF Score
Price MXN26.20
GF Value MXN19.15
Valuation Significantly Overvalued
! 4 Warning Signs
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What is OPKO Health Cyclically Adjusted FCF per Share?

OPKO Health MEX:OPK 53 Cyclically Adjusted FCF per Share is MXN-3.32 as of Mar. 2026. GuruFocus rates MEX:OPK with a GF Score™ of 53/100 and a GF Value™ of MXN19.15 (Significantly Overvalued). The stock has 4 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted FCF per Share and the Cyclically Adjusted Price-to-FCF. The Cyclically Adjusted FCF per Share is the average of the inflation adjusted Free Cash Flow per Share of a company over the past 10 years.

OPKO Health's adjusted free cash flow per share for the three months ended in Mar. 2026 was MXN-0.502. Add all the adjusted free cash flow per share for the past 10 years together and divide the count will get our Cyclically Adjusted FCF per Share, which is MXN-3.32 for the trailing ten years ended in Mar. 2026.

During the past 3 years, the average Cyclically Adjusted FCF Growth Rate was -17.80% per year. During the past 5 years, the average Cyclically Adjusted FCF Growth Rate was -8.50% per year. During the past 10 years, the average Cyclically Adjusted FCF Growth Rate was -6.70% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the Cyclically Adjusted FCF Growth Rate using Cyclically Adjusted FCF per Share data.

During the past 13 years, the highest 3-Year average Cyclically Adjusted FCF Growth Rate of OPKO Health was 23.90% per year. The lowest was -17.80% per year. And the median was 6.80% per year.

As of today (2026-07-13), OPKO Health's current stock price is MXN26.20. OPKO Health's Cyclically Adjusted FCF per Share for the quarter that ended in Mar. 2026 was MXN-3.32. OPKO Health's Cyclically Adjusted Price-to-FCF of today is .


OPKO Health  (MEX:OPK) Cyclically Adjusted FCF per Share Explanation

If a company grows much fast than inflation, Cyclically Adjusted FCF per Share may underestimate the company's free cash flow. Cyclically Adjusted Price-to-FCF can seem to be too high even the actual Price-to-Free-Cash-Flow is low.

For the Cyclically Adjusted Price-to-FCF, the free cash flow per share of the past 10 years are inflation-adjusted and averaged. The result is used for P/FCF calculation. Since it looks at the average over the last 10 years, the Cyclically Adjusted Price-to-FCF is also called CAPFCF Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Price-to-FCF. The Cyclically Adjusted FCF per Share is the average of the inflation adjusted free cash flow per share of a company over the past 10 years.


Be Aware

Cyclically Adjusted Price-to-FCF works better for cyclical companies. It gives you a better idea on the company's real free cash flow value.


OPKO Health Cyclically Adjusted FCF per Share Related Terms


OPKO Health Cyclically Adjusted FCF per Share Historical Data

* Premium members only.

The historical data trend for OPKO Health's Cyclically Adjusted FCF per Share can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

OPKO Health Cyclically Adjusted FCF per Share Chart

OPKO Health Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted FCF per Share
Get a 7-Day Free Trial Premium Member Only Premium Member Only -2.16 -2.35 -1.68 -2.23 -3.47

OPKO Health Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted FCF per Share Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -3.68 -3.43 -2.90 -3.47 -3.32

MEX:OPK vs PSNL, CDNA, CSTL: Cyclically Adjusted FCF per Share Comparison

For the Diagnostics & Research subindustry, OPKO Health's Cyclically Adjusted Price-to-FCF, along with its competitors' market caps and Cyclically Adjusted Price-to-FCF data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


OPKO Health Cyclically Adjusted Price-to-FCF vs Medical Diagnostics & Research Industry

For the Medical Diagnostics & Research industry and Healthcare sector, OPKO Health's Cyclically Adjusted Price-to-FCF distribution charts can be found below:

* The bar in red indicates where OPKO Health's Cyclically Adjusted Price-to-FCF falls into.


MEX:OPK
53GF Score
OPKO Health Inc MEX:OPK
Cyclically Adjusted FCF per Share is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

OPKO Health Cyclically Adjusted FCF per Share Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted FCF per Share and the Cyclically Adjusted Price-to-FCF. The Cyclically Adjusted FCF per Share is the average of the inflation adjusted Free Cash Flow per Share of a company over the past 10 years.

What is Cyclically Adjusted FCF per Share? How do we calculate Cyclically Adjusted FCF per Share?

Cyclically Adjusted FCF per Share is the average of the inflation adjusted Free Cash Flow per Share of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the Cyclically Adjusted FCF per Share of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the free cash flow per share from 2001 through 2010.

We adjusted the 2001 free cash flow per share data with the total inflation from 2001 through 2010 to the equivalent free cash flow in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart's free cash flow is $1 a share in 2001, then the 2001's equivalent free cash flow in 2010 is $1.4 a share. If Wal-Mart's free cash flow is $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 free cash flow in 2010 is $1.35. So on and so forth, you get the equivalent free cash flow per share of past 10 years. Then you add them together and divided the sum by the count to get Cyclically Adjusted FCF per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, OPKO Health's adjusted Free Cash Flow per Share data for the three months ended in Mar. 2026 was:

Adj_FreeCashFlowPerShare= Free Cash Flow per Share /CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=-0.502/330.2130*330.2130
=-0.502

Current CPI (Mar. 2026) = 330.2130.

OPKO Health Quarterly Data

Free Cash Flow per Share CPI Adj_FreeCashFlowPerShare
201606 1.321 241.018 1.810
201609 -1.437 241.428 -1.965
201612 1.029 241.432 1.407
201703 -1.465 243.801 -1.984
201706 -0.959 244.955 -1.293
201709 -1.715 246.819 -2.294
201712 -0.434 246.524 -0.581
201803 -1.347 249.554 -1.782
201806 -0.839 251.989 -1.099
201809 -1.133 252.439 -1.482
201812 -1.290 251.233 -1.696
201903 -1.718 254.202 -2.232
201906 -1.872 256.143 -2.413
201909 -0.886 256.759 -1.139
201912 -1.512 256.974 -1.943
202003 -1.793 258.115 -2.294
202006 -0.935 257.797 -1.198
202009 1.837 260.280 2.331
202012 0.853 260.474 1.081
202103 0.536 264.877 0.668
202106 -0.751 271.696 -0.913
202109 0.825 274.310 0.993
202112 -0.389 278.802 -0.461
202203 -0.757 287.504 -0.869
202206 -0.476 296.311 -0.530
202209 -1.068 296.808 -1.188
202212 -0.984 296.797 -1.095
202303 -0.616 301.836 -0.674
202306 -0.145 305.109 -0.157
202309 0.670 307.789 0.719
202312 -0.933 306.746 -1.004
202403 -0.939 312.332 -0.993
202406 -0.884 314.175 -0.929
202409 -1.677 315.301 -1.756
202412 -1.535 315.605 -1.606
202503 -1.150 319.799 -1.187
202506 -2.072 322.561 -2.121
202509 -0.889 324.800 -0.904
202512 -0.672 324.054 -0.685
202603 -0.502 330.213 -0.502

Add all the adjusted free cash flow per share together and divide 10 will get our Cyclically Adjusted FCF per Share.

What does a Cyclically Adjusted FCF per Share of MXN-3.32 mean?
OPKO Health (MEX:OPK) has a Cyclically Adjusted FCF per Share of MXN-3.32 as of Mar. 2026. Cyclically Adjusted FCF per Share represents the company's inflation-adjusted FCF per share over a 10-year period. View historical data on OPKO Health and its competitors.
Is OPKO Health's Cyclically Adjusted FCF per Share too high?
OPKO Health's current Cyclically Adjusted FCF per Share is MXN-3.32. Overall, OPKO Health has a GF Score™ of 53/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does OPKO Health's Cyclically Adjusted FCF per Share compare to PSNL and CDNA?
OPKO Health's Cyclically Adjusted FCF per Share of MXN-3.32 can be compared against companies in the Medical Diagnostics & Research industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted FCF per Share for a Medical Diagnostics & Research company?
A good Cyclically Adjusted FCF per Share depends on the Medical Diagnostics & Research industry context. However, Cyclically Adjusted FCF per Share should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted FCF per Share mean?
A high Cyclically Adjusted FCF per Share can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted FCF per Share represents the company's inflation-adjusted FCF per share over a 10-year period. View historical data on OPKO Health and its competitors. OPKO Health's current Cyclically Adjusted FCF per Share is MXN-3.32. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is OPKO Health stock overvalued right now?
Based on GuruFocus' analysis, OPKO Health (MEX:OPK) is currently considered Significantly Overvalued. The stock's GF Value™ is MXN19.15, compared to a current price of MXN26.20 — trading 36.8% above its estimated fair value. The current Cyclically Adjusted FCF per Share is MXN-3.32. OPKO Health's overall GF Score™ is 53/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted FCF per Share calculated?
Cyclically Adjusted FCF per Share is calculated from a company's financial statements. For OPKO Health (MEX:OPK), the current Cyclically Adjusted FCF per Share is MXN-3.32 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is OPKO Health (MEX:OPK) Overvalued in 2026?

Based on GuruFocus' analysis, OPKO Health stock appears to be overvalued. The current stock price of MXN26.20 is trading 36.8% above its estimated GF Value™ of MXN19.15. GuruFocus considers OPKO Health to be Significantly Overvalued.

Key valuation signals for MEX:OPK:

  • Cyclically Adjusted FCF per Share: MXN-3.32
  • GF Value™: MXN19.15 vs. price of MXN26.20 (36.8% above fair value)
  • GF Score™: 53/100 with 4 warning signs

No single metric tells the full story. See the MEX:OPK stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


OPKO Health Business Description

Address 4400 Biscayne Boulevard, Miami, FL, USA, 33137
OPKO Health Inc is a diversified biotechnology company that operates pharmaceutical and diagnostic development programs. Its segments include pharmaceutical and diagnostics. The Pharmaceutical segment consists of its pharmaceutical operations in Chile, Mexico, Ireland, Israel, Spain, Ecuador, France, the United States, and its pharmaceutical research and development operations. The Diagnostics segment consists of clinical and genomics laboratory operations through BioReference and point-of-care operations. It generates the majority of its revenue from the Diagnostics segment.
53GF Score

Get the complete analysis for MEX:OPK

Cyclically Adjusted FCF per Share is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

MXN26.20
Price
MXN19.15
GF Value