NSHSF (Nanosphere Health Sciences) Cyclically Adjusted FCF per Share: $-0.19 (As of Dec. 2025)


What is Nanosphere Health Sciences Cyclically Adjusted FCF per Share?

Nanosphere Health Sciences NSHSF Cyclically Adjusted FCF per Share is $-0.19 as of Dec. 2025.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted FCF per Share and the Cyclically Adjusted Price-to-FCF. The Cyclically Adjusted FCF per Share is the average of the inflation adjusted Free Cash Flow per Share of a company over the past 10 years.

Nanosphere Health Sciences's adjusted free cash flow per share for the three months ended in Dec. 2025 was $-0.003. Add all the adjusted free cash flow per share for the past 10 years together and divide the count will get our Cyclically Adjusted FCF per Share, which is $-0.19 for the trailing ten years ended in Dec. 2025.

During the past 3 years, the average Cyclically Adjusted FCF Growth Rate was 56.20% per year. During the past 5 years, the average Cyclically Adjusted FCF Growth Rate was 64.00% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the Cyclically Adjusted FCF Growth Rate using Cyclically Adjusted FCF per Share data.

During the past 13 years, the highest 3-Year average Cyclically Adjusted FCF Growth Rate of Nanosphere Health Sciences was 76.10% per year. The lowest was 1.30% per year. And the median was 62.10% per year.

As of today (2026-07-08), Nanosphere Health Sciences's current stock price is $0.01. Nanosphere Health Sciences's Cyclically Adjusted FCF per Share for the quarter that ended in Dec. 2025 was $-0.19. Nanosphere Health Sciences's Cyclically Adjusted Price-to-FCF of today is .


Nanosphere Health Sciences  (OTCPK:NSHSF) Cyclically Adjusted FCF per Share Explanation

If a company grows much fast than inflation, Cyclically Adjusted FCF per Share may underestimate the company's free cash flow. Cyclically Adjusted Price-to-FCF can seem to be too high even the actual Price-to-Free-Cash-Flow is low.

For the Cyclically Adjusted Price-to-FCF, the free cash flow per share of the past 10 years are inflation-adjusted and averaged. The result is used for P/FCF calculation. Since it looks at the average over the last 10 years, the Cyclically Adjusted Price-to-FCF is also called CAPFCF Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Price-to-FCF. The Cyclically Adjusted FCF per Share is the average of the inflation adjusted free cash flow per share of a company over the past 10 years.


Be Aware

Cyclically Adjusted Price-to-FCF works better for cyclical companies. It gives you a better idea on the company's real free cash flow value.


Nanosphere Health Sciences Cyclically Adjusted FCF per Share Related Terms


Nanosphere Health Sciences Cyclically Adjusted FCF per Share Historical Data

* Premium members only.

The historical data trend for Nanosphere Health Sciences's Cyclically Adjusted FCF per Share can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Nanosphere Health Sciences Cyclically Adjusted FCF per Share Chart

Nanosphere Health Sciences Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted FCF per Share
Get a 7-Day Free Trial Premium Member Only Premium Member Only -11.39 -1.89 -0.17 -0.24 -0.19

Nanosphere Health Sciences Quarterly Data
Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25
Cyclically Adjusted FCF per Share Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -0.24 -0.22 -0.04 -0.25 -0.19

NSHSF vs VRTX, REGN, ALNY: Cyclically Adjusted FCF per Share Comparison

For the Biotechnology subindustry, Nanosphere Health Sciences's Cyclically Adjusted Price-to-FCF, along with its competitors' market caps and Cyclically Adjusted Price-to-FCF data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Nanosphere Health Sciences Cyclically Adjusted Price-to-FCF vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Nanosphere Health Sciences's Cyclically Adjusted Price-to-FCF distribution charts can be found below:

* The bar in red indicates where Nanosphere Health Sciences's Cyclically Adjusted Price-to-FCF falls into.



Nanosphere Health Sciences Cyclically Adjusted FCF per Share Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted FCF per Share and the Cyclically Adjusted Price-to-FCF. The Cyclically Adjusted FCF per Share is the average of the inflation adjusted Free Cash Flow per Share of a company over the past 10 years.

What is Cyclically Adjusted FCF per Share? How do we calculate Cyclically Adjusted FCF per Share?

Cyclically Adjusted FCF per Share is the average of the inflation adjusted Free Cash Flow per Share of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the Cyclically Adjusted FCF per Share of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the free cash flow per share from 2001 through 2010.

We adjusted the 2001 free cash flow per share data with the total inflation from 2001 through 2010 to the equivalent free cash flow in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart's free cash flow is $1 a share in 2001, then the 2001's equivalent free cash flow in 2010 is $1.4 a share. If Wal-Mart's free cash flow is $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 free cash flow in 2010 is $1.35. So on and so forth, you get the equivalent free cash flow per share of past 10 years. Then you add them together and divided the sum by the count to get Cyclically Adjusted FCF per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, Nanosphere Health Sciences's adjusted Free Cash Flow per Share data for the three months ended in Dec. 2025 was:

Adj_FreeCashFlowPerShare= Free Cash Flow per Share /CPI of Dec. 2025 (Change)*Current CPI (Dec. 2025)
=-0.003/130.3661*130.3661
=-0.003

Current CPI (Dec. 2025) = 130.3661.

Nanosphere Health Sciences Quarterly Data

Free Cash Flow per Share CPI Adj_FreeCashFlowPerShare
201603 -0.050 101.054 -0.065
201606 -0.046 102.002 -0.059
201609 -0.175 101.765 -0.224
201612 -0.077 101.449 -0.099
201703 -0.248 102.634 -0.315
201706 -0.235 103.029 -0.297
201709 -0.179 103.345 -0.226
201712 -0.098 103.345 -0.124
201803 -0.231 105.004 -0.287
201806 -0.230 105.557 -0.284
201809 -0.131 105.636 -0.162
201812 -0.142 105.399 -0.176
201903 -0.127 106.979 -0.155
201906 -0.101 107.690 -0.122
201909 0.039 107.611 0.047
201912 -0.020 107.769 -0.024
202003 -0.009 107.927 -0.011
202006 0.001 108.401 0.001
202009 0.000 108.164 0.000
202012 -0.001 108.559 -0.001
202103 -0.001 110.298 -0.001
202106 0.000 111.720 0.000
202109 -0.006 112.905 -0.007
202112 -0.002 113.774 -0.002
202203 0.000 117.646 0.000
202206 -0.004 120.806 -0.004
202209 -0.004 120.648 -0.004
202212 0.002 120.964 0.002
202303 -0.002 122.702 -0.002
202306 0.000 124.203 0.000
202309 -0.003 125.230 -0.003
202312 -0.001 125.072 -0.001
202403 0.001 126.258 0.001
202406 0.002 127.522 0.002
202409 -0.005 127.285 -0.005
202412 -0.001 127.364 -0.001
202503 0.005 129.181 0.005
202506 0.002 129.892 0.002
202509 -0.006 130.287 -0.006
202512 -0.003 130.366 -0.003

Add all the adjusted free cash flow per share together and divide 10 will get our Cyclically Adjusted FCF per Share.

What does a Cyclically Adjusted FCF per Share of $-0.19 mean?
Nanosphere Health Sciences (NSHSF) has a Cyclically Adjusted FCF per Share of $-0.19 as of Dec. 2025. Cyclically Adjusted FCF per Share represents the company's inflation-adjusted FCF per share over a 10-year period. View historical data on Nanosphere Health Sciences and its competitors.
Is Nanosphere Health Sciences' Cyclically Adjusted FCF per Share too high?
Nanosphere Health Sciences' current Cyclically Adjusted FCF per Share is $-0.19.
How does Nanosphere Health Sciences' Cyclically Adjusted FCF per Share compare to VRTX and REGN?
Nanosphere Health Sciences' Cyclically Adjusted FCF per Share of $-0.19 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted FCF per Share for a Biotechnology company?
A good Cyclically Adjusted FCF per Share depends on the Biotechnology industry context. However, Cyclically Adjusted FCF per Share should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted FCF per Share mean?
A high Cyclically Adjusted FCF per Share can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted FCF per Share represents the company's inflation-adjusted FCF per share over a 10-year period. View historical data on Nanosphere Health Sciences and its competitors. Nanosphere Health Sciences's current Cyclically Adjusted FCF per Share is $-0.19. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Nanosphere Health Sciences stock overvalued right now?
Nanosphere Health Sciences (NSHSF) has a current Cyclically Adjusted FCF per Share of $-0.19. The current Cyclically Adjusted FCF per Share is $-0.19. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted FCF per Share calculated?
Cyclically Adjusted FCF per Share is calculated from a company's financial statements. For Nanosphere Health Sciences (NSHSF), the current Cyclically Adjusted FCF per Share is $-0.19 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Nanosphere Health Sciences Business Description

Other Exchanges 2CG:GermanyNSHS:Canada
Address 605 Robson Street, c/o Suite 430, Vancouver, BC, CAN, V6B 5J3
Nanosphere Health Sciences Inc is a biotechnology company focused on providing next generation delivery of biologically active compounds through licensing and joint venture arrangements. The Company has developed and is commercializing its patented NanoSphere Delivery System, a nanotechnology platform for the delivery of biological agents such as cannabinoids, supplements, nutraceuticals, and over-the-counter medications for the cannabis, pharmaceutical, and animal health industries. The NanoSphere Delivery System provides improved bioavailability, efficacy, and onset of effect over traditional delivery systems.