Lakefront Biotherapeutics NV (CHIX:LKFTA) Cyclically Adjusted PB Ratio: 0.60 (As of Aug. 09, 2026) — 51% Below Median

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

CHIX:LKFTA Lakefront Biotherapeutics NV CHIX:LKFTA
60 GF Score
Price €23.92
GF Value €109.60
Valuation Possible Value Trap
! 4 Warning Signs
View Full Analysis

What is Lakefront Biotherapeutics NV Cyclically Adjusted PB Ratio?

Lakefront Biotherapeutics NV CHIX:LKFTA 60 Cyclically Adjusted PB Ratio is 0.60 as of Aug. 09, 2026, which is 51% below its 10-year median of 1.22. GuruFocus rates CHIX:LKFTA with a GF Score™ of 60/100 and a GF Value™ of €109.60 (Possible Value Trap). The stock has 4 warning signs investors should review. Among 693 Biotechnology companies, Lakefront Biotherapeutics NV ranks better than 72.29% on this metric.

As of today (2026-08-09), Lakefront Biotherapeutics NV's current share price is €23.92. Lakefront Biotherapeutics NV's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 was €39.91. Lakefront Biotherapeutics NV's Cyclically Adjusted PB Ratio for today is 0.60.

The historical rank and industry rank for Lakefront Biotherapeutics NV's Cyclically Adjusted PB Ratio or its related term are showing as below:

CHIX:LKFTa' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 0.58   Med: 1.22   Max: 11.89
Current: 0.58

During the past years, Lakefront Biotherapeutics NV's highest Cyclically Adjusted PB Ratio was 11.89. The lowest was 0.58. And the median was 1.22.

CHIX:LKFTa's Cyclically Adjusted PB Ratio is ranked better than
72.29% of 693 companies
in the Biotechnology industry
Industry Median: 1.62 vs CHIX:LKFTa: 0.58

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Lakefront Biotherapeutics NV's adjusted book value per share data for the three months ended in Mar. 2026 was €49.371. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is €39.91 for the trailing ten years ended in Mar. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


Lakefront Biotherapeutics NV  (CHIX:LKFTa) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


Lakefront Biotherapeutics NV Cyclically Adjusted PB Ratio Related Terms


Lakefront Biotherapeutics NV Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for Lakefront Biotherapeutics NV's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Lakefront Biotherapeutics NV Cyclically Adjusted PB Ratio Chart

Lakefront Biotherapeutics NV Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 2.26 1.49 1.16 0.74 0.72

Lakefront Biotherapeutics NV Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.63 0.64 0.77 0.72 0.65

CHIX:LKFTA vs VRTX, REGN, RVMD: Cyclically Adjusted PB Ratio Comparison

For the Biotechnology subindustry, Lakefront Biotherapeutics NV's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Lakefront Biotherapeutics NV Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Lakefront Biotherapeutics NV's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Lakefront Biotherapeutics NV's Cyclically Adjusted PB Ratio falls into.


CHIX:LKFTA
60GF Score
Lakefront Biotherapeutics NV CHIX:LKFTA
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Lakefront Biotherapeutics NV Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

Lakefront Biotherapeutics NV's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=23.92/39.91
=0.60

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Lakefront Biotherapeutics NV's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 is calculated as:

For example, Lakefront Biotherapeutics NV's adjusted Book Value per Share data for the three months ended in Mar. 2026 was:

Adj_Book=Book Value per Share/CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=49.371/136.5600*136.5600
=49.371

Current CPI (Mar. 2026) = 136.5600.

Lakefront Biotherapeutics NV Quarterly Data

Book Value per Share CPI Adj_Book
201606 15.827 102.267 21.134
201609 15.324 102.118 20.492
201612 16.402 102.614 21.828
201703 16.174 103.972 21.243
201706 21.016 103.902 27.622
201709 0.000 104.170 0.000
201712 19.867 104.804 25.887
201803 17.553 105.419 22.738
201806 17.252 106.063 22.213
201809 21.883 106.618 28.029
201812 22.294 107.252 28.386
201903 21.528 107.876 27.252
201906 20.856 107.896 26.397
201909 40.922 107.470 51.999
201912 44.469 108.065 56.195
202003 43.815 108.550 55.121
202006 42.499 108.540 53.470
202009 41.507 108.441 52.270
202012 40.824 108.511 51.377
202103 41.236 109.522 51.416
202106 40.649 110.305 50.325
202109 39.942 111.543 48.900
202112 40.324 114.705 48.007
202203 40.315 118.620 46.412
202206 40.270 120.948 45.468
202209 40.864 124.120 44.960
202212 38.368 126.578 41.394
202303 38.918 126.528 42.004
202306 39.212 125.973 42.507
202309 39.783 127.083 42.750
202312 42.423 128.292 45.157
202403 43.932 130.552 45.954
202406 44.164 130.691 46.147
202409 43.440 130.968 45.295
202412 43.962 132.346 45.362
202503 41.700 134.348 42.387
202506 40.120 133.495 41.041
202509 37.133 133.740 37.916
202512 49.105 135.070 49.647
202603 49.371 136.560 49.371

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 0.60 mean?
Lakefront Biotherapeutics NV (CHIX:LKFTA) has a Cyclically Adjusted PB Ratio of 0.60 as of Aug. 09, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Lakefront Biotherapeutics NV and its competitors. This is 51% below median its historical median of 1.22. Over the past decade, Lakefront Biotherapeutics NV's Cyclically Adjusted PB Ratio has ranged from 0.58 to 11.89. According to the industry distribution chart, Lakefront Biotherapeutics NV ranks #192 out of 693 companies in the Biotechnology industry, placing it in the top 27.7%.
Is Lakefront Biotherapeutics NV's Cyclically Adjusted PB Ratio too high?
Lakefront Biotherapeutics NV's current Cyclically Adjusted PB Ratio of 0.60 is 51% below median its 10-year median of 1.22. Over the past 10 years, this metric has ranged from a low of 0.58 to a high of 11.89. The Biotechnology industry median Cyclically Adjusted PB Ratio is 1.62. Lakefront Biotherapeutics NV's value of 0.60 is 63% below this industry median. Based on the distribution chart, Lakefront Biotherapeutics NV ranks #192 out of 693 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Lakefront Biotherapeutics NV has a GF Score™ of 60/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does Lakefront Biotherapeutics NV's Cyclically Adjusted PB Ratio compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Lakefront Biotherapeutics NV ranks #192 out of 693 companies for Cyclically Adjusted PB Ratio. This puts Lakefront Biotherapeutics NV in the upper half of its industry. The industry median Cyclically Adjusted PB Ratio is 1.62. Lakefront Biotherapeutics NV's value of 0.60 is 63% below this benchmark. Historically, Lakefront Biotherapeutics NV's own Cyclically Adjusted PB Ratio has ranged from 0.58 to 11.89 over the past decade. While the company's 10-year median is 1.22 vs. the industry median of 1.62, Lakefront Biotherapeutics NV has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Biotechnology company?
The median Cyclically Adjusted PB Ratio among Biotechnology companies is 1.62, based on 693 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Lakefront Biotherapeutics NV's current Cyclically Adjusted PB Ratio of 0.60 is 63% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Lakefront Biotherapeutics NV and its competitors. For the Biotechnology industry, the median Cyclically Adjusted PB Ratio is 1.62 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Lakefront Biotherapeutics NV's current Cyclically Adjusted PB Ratio is 0.60, which is 51% below median its own 10-year median of 1.22. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Lakefront Biotherapeutics NV stock overvalued right now?
Based on GuruFocus' analysis, Lakefront Biotherapeutics NV (CHIX:LKFTA) is currently considered Possible Value Trap. The stock's GF Value™ is €109.60, compared to a current price of €23.92 — trading 78.2% below its estimated fair value. The current Cyclically Adjusted PB Ratio is 0.60, which is 51% below median its 10-year median of 1.22 and 63% below the Biotechnology industry median of 1.62. Lakefront Biotherapeutics NV's overall GF Score™ is 60/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Lakefront Biotherapeutics NV (CHIX:LKFTA), the current Cyclically Adjusted PB Ratio is 0.60 as of Aug. 09, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Lakefront Biotherapeutics NV (CHIX:LKFTA) Overvalued in 2026?

Based on GuruFocus' analysis, Lakefront Biotherapeutics NV stock appears to be undervalued. The current stock price of €23.92 is trading 78.2% below its estimated GF Value™ of €109.60. GuruFocus considers Lakefront Biotherapeutics NV to be Possible Value Trap.

Key valuation signals for CHIX:LKFTA:

  • Cyclically Adjusted PB Ratio: 0.60 (51% below median its 10-year median of 1.22)
  • GF Value™: €109.60 vs. price of €23.92 (78.2% below fair value)
  • GF Score™: 60/100 with 4 warning signs
  • Industry Position: 63% below the Biotechnology median (#192 of 693)

No single metric tells the full story. See the CHIX:LKFTA stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Lakefront Biotherapeutics NV Business Description

Address Schalienhoevedreef 20 T, Mechelen, BEL, 2800
Lakefront Biotherapeutics NV a biopharmaceutical company committed to improving the lives of people with severe diseases. It focuses on delivering medicines with transformational impact for patients by accelerating life-changing science and innovation in areas of high unmet need. Its pipelines includes GLPG3667, GLPG5101, and GLPG5301.
60GF Score

Get the complete analysis for CHIX:LKFTA

Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€23.92
Price
€109.60
GF Value