Nanosphere Health Sciences (FRA:2CG) Cyclically Adjusted PB Ratio: (As of Jul. 24, 2026)

Author: Vera Yuan Vera Yuan
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What is Nanosphere Health Sciences Cyclically Adjusted PB Ratio?

Shiller PE for Stocks: The True Measure of Stock Valuation


Nanosphere Health Sciences  (FRA:2CG) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


Nanosphere Health Sciences Cyclically Adjusted PB Ratio Related Terms


Nanosphere Health Sciences Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for Nanosphere Health Sciences's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Nanosphere Health Sciences Cyclically Adjusted PB Ratio Chart

Nanosphere Health Sciences Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.02 0.01 0.00 1.41 0.46

Nanosphere Health Sciences Quarterly Data
Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 1.41 1.71 0.66 0.58 0.46

FRA:2CG vs VRTX, REGN, ALNY: Cyclically Adjusted PB Ratio Comparison

For the Biotechnology subindustry, Nanosphere Health Sciences's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Nanosphere Health Sciences Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Nanosphere Health Sciences's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Nanosphere Health Sciences's Cyclically Adjusted PB Ratio falls into.



Nanosphere Health Sciences Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

Nanosphere Health Sciences's Cyclically Adjusted Book per Share for the quarter that ended in Dec. 2025 is calculated as:

For example, Nanosphere Health Sciences's adjusted Book Value per Share data for the three months ended in Dec. 2025 was:

Adj_Book=Book Value per Share/CPI of Dec. 2025 (Change)*Current CPI (Dec. 2025)
=-0.112/130.3661*130.3661
=-0.112

Current CPI (Dec. 2025) = 130.3661.

Nanosphere Health Sciences Quarterly Data

Book Value per Share CPI Adj_Book
201603 -0.170 101.054 -0.219
201606 -0.228 102.002 -0.291
201609 0.670 101.765 0.858
201612 -0.261 101.449 -0.335
201703 0.584 102.634 0.742
201706 0.531 103.029 0.672
201709 0.844 103.345 1.065
201712 0.647 103.345 0.816
201803 0.466 105.004 0.579
201806 0.371 105.557 0.458
201809 0.217 105.636 0.268
201812 0.145 105.399 0.179
201903 0.267 106.979 0.325
201906 0.175 107.690 0.212
201909 0.071 107.611 0.086
201912 -0.153 107.769 -0.185
202003 -0.182 107.927 -0.220
202006 -0.197 108.401 -0.237
202009 -0.199 108.164 -0.240
202012 -0.221 108.559 -0.265
202103 -0.236 110.298 -0.279
202106 -0.254 111.720 -0.296
202109 -0.083 112.905 -0.096
202112 -0.093 113.774 -0.107
202203 -0.102 117.646 -0.113
202206 -0.112 120.806 -0.121
202209 -0.119 120.648 -0.129
202212 -0.121 120.964 -0.130
202303 -0.124 122.702 -0.132
202306 -0.131 124.203 -0.138
202309 -0.135 125.230 -0.141
202312 -0.139 125.072 -0.145
202403 -0.141 126.258 -0.146
202406 -0.147 127.522 -0.150
202409 -0.148 127.285 -0.152
202412 -0.113 127.364 -0.116
202503 -0.118 129.181 -0.119
202506 -0.117 129.892 -0.117
202509 -0.114 130.287 -0.114
202512 -0.112 130.366 -0.112

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.


Nanosphere Health Sciences Business Description

Other Exchanges NSHSF:USANSHS:Canada
Address 605 Robson Street, c/o Suite 430, Vancouver, BC, CAN, V6B 5J3
Nanosphere Health Sciences Inc is a biotechnology company focused on providing next generation delivery of biologically active compounds through licensing and joint venture arrangements. The Company has developed and is commercializing its patented NanoSphere Delivery System, a nanotechnology platform for the delivery of biological agents such as cannabinoids, supplements, nutraceuticals, and over-the-counter medications for the cannabis, pharmaceutical, and animal health industries. The NanoSphere Delivery System provides improved bioavailability, efficacy, and onset of effect over traditional delivery systems.