Synthaverse (FRA:6NQ) Cyclically Adjusted PB Ratio: 2.23 (As of Sep. 03, 2026) — 41% Below Median

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FRA:6NQ Synthaverse SA FRA:6NQ
55 GF Score
Price €0.69
GF Value €0.69
! 8 Warning Signs
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What is Synthaverse Cyclically Adjusted PB Ratio?

Synthaverse FRA:6NQ -0.58% 55 Cyclically Adjusted PB Ratio is 2.23 as of Sep. 03, 2026, which is 41% below its 10-year median of 3.75. GuruFocus rates FRA:6NQ with a GF Score™ of 55/100 and a GF Value™ of €0.69. The stock has 8 warning signs investors should review. Among 684 Biotechnology companies, Synthaverse ranks worse than 58.92% on this metric.

As of today (2026-09-03), Synthaverse's current share price is €0.691. Synthaverse's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 was €0.31. Synthaverse's Cyclically Adjusted PB Ratio for today is 2.23.

The historical rank and industry rank for Synthaverse's Cyclically Adjusted PB Ratio or its related term are showing as below:

FRA:6NQ' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 1.96   Med: 3.75   Max: 9.61
Current: 2.24

During the past years, Synthaverse's highest Cyclically Adjusted PB Ratio was 9.61. The lowest was 1.96. And the median was 3.75.

FRA:6NQ's Cyclically Adjusted PB Ratio is ranked worse than
58.92% of 684 companies
in the Biotechnology industry
Industry Median: 1.615 vs FRA:6NQ: 2.24

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Synthaverse's adjusted book value per share data for the three months ended in Mar. 2026 was €0.370. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is €0.31 for the trailing ten years ended in Mar. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


Synthaverse  (FRA:6NQ) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


Synthaverse Cyclically Adjusted PB Ratio Related Terms


Synthaverse Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for Synthaverse's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Synthaverse Cyclically Adjusted PB Ratio Chart

Synthaverse Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 4.24 4.90 3.37 3.49 2.83

Synthaverse Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 3.53 4.03 3.35 2.83 2.76

FRA:6NQ vs VRTX, REGN, MRNA: Cyclically Adjusted PB Ratio Comparison

For the Biotechnology subindustry, Synthaverse's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Synthaverse Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Synthaverse's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Synthaverse's Cyclically Adjusted PB Ratio falls into.


FRA:6NQ
55GF Score
Synthaverse SA FRA:6NQ
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Synthaverse Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

Synthaverse's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=0.691/0.31
=2.23

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Synthaverse's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 is calculated as:

For example, Synthaverse's adjusted Book Value per Share data for the three months ended in Mar. 2026 was:

Adj_Book=Book Value per Share/CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=0.37/163.0700*163.0700
=0.370

Current CPI (Mar. 2026) = 163.0700.

Synthaverse Quarterly Data

Book Value per Share CPI Adj_Book
201606 0.054 99.552 0.088
201609 0.037 99.064 0.061
201612 0.225 100.366 0.366
201703 0.249 101.018 0.402
201706 0.197 101.180 0.318
201709 0.175 101.343 0.282
201712 0.233 102.564 0.370
201803 0.251 102.564 0.399
201806 0.229 103.378 0.361
201809 0.225 103.378 0.355
201812 0.113 103.785 0.178
201903 0.114 104.274 0.178
201906 0.115 105.983 0.177
201909 0.116 105.983 0.178
201912 0.122 107.123 0.186
202003 0.126 109.076 0.188
202006 0.125 109.402 0.186
202009 0.125 109.320 0.186
202012 0.138 109.565 0.205
202103 0.134 112.658 0.194
202106 0.000 113.960 0.000
202109 0.212 115.588 0.299
202112 0.264 119.088 0.362
202203 0.261 125.031 0.340
202206 0.271 131.705 0.336
202209 0.276 135.531 0.332
202212 0.347 139.113 0.407
202303 0.350 145.950 0.391
202306 0.361 147.009 0.400
202309 0.353 146.113 0.394
202312 0.369 147.741 0.407
202403 0.368 149.044 0.403
202406 0.372 150.997 0.402
202409 0.373 153.439 0.396
202412 0.398 154.660 0.420
202503 0.395 157.021 0.410
202506 0.379 157.509 0.392
202509 0.426 158.000 0.440
202512 0.380 158.320 0.391
202603 0.370 163.070 0.370

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 2.23 mean?
Synthaverse (FRA:6NQ) has a Cyclically Adjusted PB Ratio of 2.23 as of Sep. 03, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Synthaverse and its competitors. This is 41% below median its historical median of 3.75. Over the past decade, Synthaverse's Cyclically Adjusted PB Ratio has ranged from 1.96 to 9.61. According to the industry distribution chart, Synthaverse ranks #403 out of 684 companies in the Biotechnology industry, placing it in the top 58.9%.
Is Synthaverse's Cyclically Adjusted PB Ratio too high?
Synthaverse's current Cyclically Adjusted PB Ratio of 2.23 is 41% below median its 10-year median of 3.75. Over the past 10 years, this metric has ranged from a low of 1.96 to a high of 9.61. The Biotechnology industry median Cyclically Adjusted PB Ratio is 1.62. Synthaverse's value of 2.23 is 38.1% above this industry median. Based on the distribution chart, Synthaverse ranks #403 out of 684 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Synthaverse has a GF Score™ of 55/100, reflecting its overall financial health beyond just this single metric.
How does Synthaverse's Cyclically Adjusted PB Ratio compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Synthaverse ranks #403 out of 684 companies for Cyclically Adjusted PB Ratio. This places Synthaverse in the lower half of its industry. The industry median Cyclically Adjusted PB Ratio is 1.62. Synthaverse's value of 2.23 is 38.1% above this benchmark. Historically, Synthaverse's own Cyclically Adjusted PB Ratio has ranged from 1.96 to 9.61 over the past decade. While the company's 10-year median is 3.75 vs. the industry median of 1.62, Synthaverse has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Biotechnology company?
The median Cyclically Adjusted PB Ratio among Biotechnology companies is 1.62, based on 684 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Synthaverse's current Cyclically Adjusted PB Ratio of 2.23 is 38.1% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Synthaverse and its competitors. For the Biotechnology industry, the median Cyclically Adjusted PB Ratio is 1.62 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Synthaverse's current Cyclically Adjusted PB Ratio is 2.23, which is 41% below median its own 10-year median of 3.75. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Synthaverse stock overvalued right now?
Synthaverse (FRA:6NQ) has a current Cyclically Adjusted PB Ratio of 2.23. The stock's GF Value™ is €0.69, compared to a current price of €0.69 — trading 0.1% above its estimated fair value. The current Cyclically Adjusted PB Ratio is 2.23, which is 41% below median its 10-year median of 3.75 and 38.1% above the Biotechnology industry median of 1.62. Synthaverse's overall GF Score™ is 55/100 with 8 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Synthaverse (FRA:6NQ), the current Cyclically Adjusted PB Ratio is 2.23 as of Sep. 03, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Synthaverse (FRA:6NQ) Overvalued in 2026?

Based on GuruFocus' analysis, Synthaverse stock appears to be overvalued. The current stock price of €0.69 is trading 0.1% above its estimated GF Value™ of €0.69.

Key valuation signals for FRA:6NQ:

  • Cyclically Adjusted PB Ratio: 2.23 (41% below median its 10-year median of 3.75)
  • GF Value™: €0.69 vs. price of €0.69 (0.1% above fair value)
  • GF Score™: 55/100 with 8 warning signs
  • Industry Position: 38.1% above the Biotechnology median (#403 of 684)

No single metric tells the full story. See the FRA:6NQ stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Synthaverse Business Description

Other Exchanges SVE:Poland
Address 10, Uniwersytecka street, Lublin, POL, 20-029
Synthaverse SA is a global pharmaceutical company. Its goal is to provide the best, innovative and unique solutions for medicine. Its work is based on scientific and health knowledge. Along with its expert approach, it allows the company to create reliable and unique products. It manufactures one of the few drugs used internationally in the oncological immunotherapy of bladder cancer.
55GF Score

Get the complete analysis for FRA:6NQ

Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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