HEPA (Hepion Pharmaceuticals) Cyclically Adjusted PB Ratio: 0.00 (As of Jul. 29, 2026)

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What is Hepion Pharmaceuticals Cyclically Adjusted PB Ratio?

Hepion Pharmaceuticals HEPA Cyclically Adjusted PB Ratio is 0.00 as of Jul. 29, 2026. The stock has 2 warning signs investors should review. Among 698 Biotechnology companies, Hepion Pharmaceuticals ranks worse than 143266.33% on this metric.

As of today (2026-07-29), Hepion Pharmaceuticals's current share price is $0.058502. Hepion Pharmaceuticals's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 was $1,371.78. Hepion Pharmaceuticals's Cyclically Adjusted PB Ratio for today is 0.00.

The historical rank and industry rank for Hepion Pharmaceuticals's Cyclically Adjusted PB Ratio or its related term are showing as below:

HEPA's Cyclically Adjusted PB Ratio is not ranked *
in the Biotechnology industry.
Industry Median: 1.59
* Ranked among companies with meaningful Cyclically Adjusted PB Ratio only.

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Hepion Pharmaceuticals's adjusted book value per share data for the three months ended in Mar. 2026 was $0.014. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is $1,371.78 for the trailing ten years ended in Mar. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


Hepion Pharmaceuticals  (OTCPK:HEPA) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


Hepion Pharmaceuticals Cyclically Adjusted PB Ratio Related Terms


Hepion Pharmaceuticals Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for Hepion Pharmaceuticals's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Hepion Pharmaceuticals Cyclically Adjusted PB Ratio Chart

Hepion Pharmaceuticals Annual Data
Trend Jun16 Jun17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.09 0.01 0.00

Hepion Pharmaceuticals Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 0.00 0.00 0.00

HEPA vs MTNB, ITRMF, VIVS: Cyclically Adjusted PB Ratio Comparison

For the Biotechnology subindustry, Hepion Pharmaceuticals's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Hepion Pharmaceuticals Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Hepion Pharmaceuticals's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Hepion Pharmaceuticals's Cyclically Adjusted PB Ratio falls into.



Hepion Pharmaceuticals Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

Hepion Pharmaceuticals's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=0.058502/1371.78
=0.00

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Hepion Pharmaceuticals's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 is calculated as:

For example, Hepion Pharmaceuticals's adjusted Book Value per Share data for the three months ended in Mar. 2026 was:

Adj_Book=Book Value per Share/CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=0.014/330.2130*330.2130
=0.014

Current CPI (Mar. 2026) = 330.2130.

Hepion Pharmaceuticals Quarterly Data

Book Value per Share CPI Adj_Book
201606 0.000 241.018 0.000
201609 0.000 241.428 0.000
201612 0.000 241.432 0.000
201703 0.000 243.801 0.000
201706 0.000 244.955 0.000
201709 0.000 246.819 0.000
201712 0.000 246.524 0.000
201803 0.000 249.554 0.000
201806 0.000 251.989 0.000
201809 0.000 252.439 0.000
201812 0.000 251.233 0.000
201903 0.000 254.202 0.000
201906 5,435.000 256.143 7,006.663
201909 4,836.667 256.759 6,220.348
201912 3,475.000 256.974 4,465.394
202003 2,841.833 258.115 3,635.628
202006 1,841.667 257.797 2,358.997
202009 1,240.111 260.280 1,573.309
202012 1,212.750 260.474 1,537.450
202103 1,524.579 264.877 1,900.640
202106 1,434.395 271.696 1,743.330
202109 1,328.105 274.310 1,598.766
202112 1,201.237 278.802 1,422.745
202203 1,117.632 287.504 1,283.657
202206 863.474 296.311 962.267
202209 757.408 296.808 842.652
202212 633.684 296.797 705.030
202303 466.539 301.836 510.400
202306 320.494 305.109 346.864
202309 187.844 307.789 201.529
202312 58.188 306.746 62.640
202403 53.450 312.332 56.510
202406 16.095 314.175 16.917
202409 -15.122 315.301 -15.837
202412 -25.597 315.605 -26.782
202503 0.230 319.799 0.237
202506 0.181 322.561 0.185
202509 0.140 324.800 0.142
202512 0.084 324.054 0.086
202603 0.014 330.213 0.014

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 0.00 mean?
Hepion Pharmaceuticals (HEPA) has a Cyclically Adjusted PB Ratio of 0.00 as of Jul. 29, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Hepion Pharmaceuticals and its competitors. According to the industry distribution chart, Hepion Pharmaceuticals ranks #999999 out of 698 companies in the Biotechnology industry.
Is Hepion Pharmaceuticals' Cyclically Adjusted PB Ratio too high?
Hepion Pharmaceuticals' current Cyclically Adjusted PB Ratio is 0.00. Based on the distribution chart, Hepion Pharmaceuticals ranks #999999 out of 698 companies in the Biotechnology industry, which is in the bottom quartile relative to peers.
How does Hepion Pharmaceuticals' Cyclically Adjusted PB Ratio compare to MTNB and ITRMF?
According to the Biotechnology industry distribution chart, Hepion Pharmaceuticals ranks #999999 out of 698 companies for Cyclically Adjusted PB Ratio. This places Hepion Pharmaceuticals in the lower half of its industry. The industry median Cyclically Adjusted PB Ratio is 1.59. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Biotechnology company?
The median Cyclically Adjusted PB Ratio among Biotechnology companies is 1.59, based on 698 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Hepion Pharmaceuticals and its competitors. For the Biotechnology industry, the median Cyclically Adjusted PB Ratio is 1.59 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Hepion Pharmaceuticals's current Cyclically Adjusted PB Ratio is 0.00. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Hepion Pharmaceuticals stock overvalued right now?
Hepion Pharmaceuticals (HEPA) has a current Cyclically Adjusted PB Ratio of 0.00. The current Cyclically Adjusted PB Ratio is 0.00. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Hepion Pharmaceuticals (HEPA), the current Cyclically Adjusted PB Ratio is 0.00 as of Jul. 29, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Hepion Pharmaceuticals Business Description

Address 55 Madison Avenue, Suite 400- PMB 4362, Morristown, NJ, USA, 07960
Hepion Pharmaceuticals Inc is a biopharmaceutical company that focuses on the development of drug therapy for the treatment of chronic liver diseases. The company is pioneering early cancer detection solutions with a novel liquid biopsy. diagnostics. The company's mission is to redefine the early detection of hepatocellular carcinoma, moving from missed diagnoses to timely, precise intervention. It's focused on delivering non-invasive, clinically grounded liquid biopsy solutions for patients at the highest risk, particularly those living with cirrhosis.