MDGEF (Medigene AG) Cyclically Adjusted PB Ratio: 0.39 (As of Jul. 20, 2026)

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MDGEF Medigene AG MDGEF
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Price $2.59
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What is Medigene AG Cyclically Adjusted PB Ratio?

Medigene AG MDGEF 12 Cyclically Adjusted PB Ratio is 0.39 as of Jul. 20, 2026. GuruFocus rates MDGEF with a GF Score™ of 12/100.

As of today (2026-07-20), Medigene AG's current share price is $2.59. Medigene AG's Cyclically Adjusted Book per Share for the fiscal year that ended in Dec23 was $6.59. Medigene AG's Cyclically Adjusted PB Ratio for today is 0.39.

The historical rank and industry rank for Medigene AG's Cyclically Adjusted PB Ratio or its related term are showing as below:

MDGEF's Cyclically Adjusted PB Ratio is not ranked *
in the Biotechnology industry.
Industry Median: 1.605
* Ranked among companies with meaningful Cyclically Adjusted PB Ratio only.

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Medigene AG's adjusted book value per share data of for the fiscal year that ended in Dec23 was $1.776. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is $6.59 for the trailing ten years ended in Dec23.

Shiller PE for Stocks: The True Measure of Stock Valuation


Medigene AG  (OTCPK:MDGEF) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


Medigene AG Cyclically Adjusted PB Ratio Related Terms


Medigene AG Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for Medigene AG's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Medigene AG Cyclically Adjusted PB Ratio Chart

Medigene AG Annual Data
Trend Dec14 Dec15 Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.89 0.84 0.72 0.52 0.42

Medigene AG Semi-Annual Data
Dec14 Jun15 Dec15 Jun16 Dec16 Jun17 Dec17 Jun18 Dec18 Jun19 Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.52 0.00 0.42 0.00

MDGEF vs VRTX, REGN, ALNY: Cyclically Adjusted PB Ratio Comparison

For the Biotechnology subindustry, Medigene AG's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Medigene AG Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Medigene AG's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Medigene AG's Cyclically Adjusted PB Ratio falls into.


MDGEF
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Medigene AG MDGEF
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
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Medigene AG Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

Medigene AG's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=2.59/6.59
=0.39

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Medigene AG's Cyclically Adjusted Book per Share for the fiscal year that ended in Dec23 is calculated as:

For example, Medigene AG's adjusted Book Value per Share data for the fiscal year that ended in Dec23 was:

Adj_Book=Book Value per Share/CPI of Dec23 (Change)*Current CPI (Dec23)
=1.776/123.7729*123.7729
=1.776

Current CPI (Dec23) = 123.7729.

Medigene AG Annual Data

Book Value per Share CPI Adj_Book
201412 8.251 99.543 10.259
201512 9.461 99.717 11.743
201612 8.789 101.217 10.748
201712 9.423 102.617 11.366
201812 9.084 104.217 10.789
201912 7.030 105.818 8.223
202012 5.000 105.518 5.865
202112 3.916 110.384 4.391
202212 3.033 119.345 3.146
202312 1.776 123.773 1.776

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 0.39 mean?
Medigene AG (MDGEF) has a Cyclically Adjusted PB Ratio of 0.39 as of Jul. 20, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Medigene AG and its competitors.
Is Medigene AG's Cyclically Adjusted PB Ratio too high?
Medigene AG's current Cyclically Adjusted PB Ratio is 0.39. The Biotechnology industry median Cyclically Adjusted PB Ratio is 1.61. Medigene AG's value of 0.39 is 75.7% below this industry median. Overall, Medigene AG has a GF Score™ of 12/100, reflecting its overall financial health beyond just this single metric.
How does Medigene AG's Cyclically Adjusted PB Ratio compare to VRTX and REGN?
Medigene AG's Cyclically Adjusted PB Ratio of 0.39 can be compared against companies in the Biotechnology industry. The industry median Cyclically Adjusted PB Ratio is 1.61. Medigene AG's value of 0.39 is 75.7% below this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Biotechnology company?
The median Cyclically Adjusted PB Ratio among Biotechnology companies is 1.61, based on 698 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Medigene AG's current Cyclically Adjusted PB Ratio of 0.39 is 75.7% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Medigene AG and its competitors. For the Biotechnology industry, the median Cyclically Adjusted PB Ratio is 1.61 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Medigene AG's current Cyclically Adjusted PB Ratio is 0.39. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Medigene AG stock overvalued right now?
Medigene AG (MDGEF) has a current Cyclically Adjusted PB Ratio of 0.39. The current Cyclically Adjusted PB Ratio is 0.39 and 75.7% below the Biotechnology industry median of 1.61. Medigene AG's overall GF Score™ is 12/100. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Medigene AG (MDGEF), the current Cyclically Adjusted PB Ratio is 0.39 as of Jul. 20, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Medigene AG Business Description

Address Lochhamer Strasse 11, Martinsried, Planegg, BY, DEU, 82152
Medigene AG is an immuno-oncology biotechnology company. focused on developing differentiated T Cell Receptor engineered T cell (TCR-T) therapies for the treatment of multiple solid tumor indications with a high unmet medical need. The operating segments of the organization are Immunotherapies and Other products. Immunotherapies consist of T-cell receptor-based adoptive T-cell therapy and DC vaccines. The group operates in the United States, Germany, and Asia, of which the majority of the revenue is derived from operations in Germany.
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