OSUR (OraSure Technologies) Cyclically Adjusted PB Ratio: 0.66 (As of Jul. 22, 2026) — 71% Below Median

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

OSUR OraSure Technologies Inc OSUR
57 GF Score
Price $3.79
GF Value $1.99
Valuation Significantly Overvalued
! 3 Warning Signs
View Full Analysis

What is OraSure Technologies Cyclically Adjusted PB Ratio?

OraSure Technologies OSUR -0.39% 57 Cyclically Adjusted PB Ratio is 0.66 as of Jul. 22, 2026, which is 71% below its 10-year median of 2.31. GuruFocus rates OSUR with a GF Score™ of 57/100 and a GF Value™ of $1.99 (Significantly Overvalued). The stock has 3 warning signs investors should review. Among 522 Medical Devices & Instruments companies, OraSure Technologies ranks better than 78.93% on this metric.

As of today (2026-07-22), OraSure Technologies's current share price is $3.785. OraSure Technologies's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 was $5.76. OraSure Technologies's Cyclically Adjusted PB Ratio for today is 0.66.

The historical rank and industry rank for OraSure Technologies's Cyclically Adjusted PB Ratio or its related term are showing as below:

OSUR' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 0.4   Med: 2.31   Max: 7.76
Current: 0.66

During the past years, OraSure Technologies's highest Cyclically Adjusted PB Ratio was 7.76. The lowest was 0.40. And the median was 2.31.

OSUR's Cyclically Adjusted PB Ratio is ranked better than
78.93% of 522 companies
in the Medical Devices & Instruments industry
Industry Median: 1.745 vs OSUR: 0.66

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

OraSure Technologies's adjusted book value per share data for the three months ended in Mar. 2026 was $4.515. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is $5.76 for the trailing ten years ended in Mar. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


OraSure Technologies  (NAS:OSUR) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


OraSure Technologies Cyclically Adjusted PB Ratio Related Terms


OraSure Technologies Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for OraSure Technologies's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

OraSure Technologies Cyclically Adjusted PB Ratio Chart

OraSure Technologies Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 2.04 1.03 1.63 0.67 0.43

OraSure Technologies Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.61 0.54 0.57 0.43 0.52

OSUR vs UTMD, SMTI, EMBC: Cyclically Adjusted PB Ratio Comparison

For the Medical Instruments & Supplies subindustry, OraSure Technologies's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


OraSure Technologies Cyclically Adjusted PB Ratio vs Medical Devices & Instruments Industry

For the Medical Devices & Instruments industry and Healthcare sector, OraSure Technologies's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where OraSure Technologies's Cyclically Adjusted PB Ratio falls into.


OSUR
57GF Score
OraSure Technologies Inc OSUR
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

OraSure Technologies Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

OraSure Technologies's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=3.785/5.76
=0.66

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

OraSure Technologies's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 is calculated as:

For example, OraSure Technologies's adjusted Book Value per Share data for the three months ended in Mar. 2026 was:

Adj_Book=Book Value per Share/CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=4.515/330.2130*330.2130
=4.515

Current CPI (Mar. 2026) = 330.2130.

OraSure Technologies Quarterly Data

Book Value per Share CPI Adj_Book
201606 3.036 241.018 4.160
201609 3.167 241.428 4.332
201612 3.319 241.432 4.539
201703 3.621 243.801 4.904
201706 3.867 244.955 5.213
201709 4.115 246.819 5.505
201712 4.254 246.524 5.698
201803 4.238 249.554 5.608
201806 4.335 251.989 5.681
201809 4.519 252.439 5.911
201812 4.625 251.233 6.079
201903 4.549 254.202 5.909
201906 4.669 256.143 6.019
201909 4.882 256.759 6.279
201912 4.976 256.974 6.394
202003 4.678 258.115 5.985
202006 5.346 257.797 6.848
202009 5.417 260.280 6.872
202012 5.556 260.474 7.044
202103 5.608 264.877 6.991
202106 5.622 271.696 6.833
202109 5.384 274.310 6.481
202112 5.280 278.802 6.254
202203 5.046 287.504 5.796
202206 4.743 296.311 5.286
202209 4.708 296.808 5.238
202212 5.010 296.797 5.574
202303 5.381 301.836 5.887
202306 5.369 305.109 5.811
202309 5.510 307.789 5.911
202312 5.857 306.746 6.305
202403 5.763 312.332 6.093
202406 5.711 314.175 6.003
202409 5.705 315.301 5.975
202412 5.501 315.605 5.756
202503 5.276 319.799 5.448
202506 5.163 322.561 5.285
202509 5.009 324.800 5.092
202512 4.842 324.054 4.934
202603 4.515 330.213 4.515

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 0.66 mean?
OraSure Technologies (OSUR) has a Cyclically Adjusted PB Ratio of 0.66 as of Jul. 22, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on OraSure Technologies and its competitors. This is 71% below median its historical median of 2.31. Over the past decade, OraSure Technologies' Cyclically Adjusted PB Ratio has ranged from 0.40 to 7.76. According to the industry distribution chart, OraSure Technologies ranks #110 out of 522 companies in the Medical Devices & Instruments industry, placing it in the top 21.1%.
Is OraSure Technologies' Cyclically Adjusted PB Ratio too high?
OraSure Technologies' current Cyclically Adjusted PB Ratio of 0.66 is 71% below median its 10-year median of 2.31. Over the past 10 years, this metric has ranged from a low of 0.40 to a high of 7.76. The Medical Devices & Instruments industry median Cyclically Adjusted PB Ratio is 1.75. OraSure Technologies' value of 0.66 is 62.2% below this industry median. Based on the distribution chart, OraSure Technologies ranks #110 out of 522 companies in the Medical Devices & Instruments industry, which is in the top quartile — a strong position relative to peers. Overall, OraSure Technologies has a GF Score™ of 57/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does OraSure Technologies' Cyclically Adjusted PB Ratio compare to UTMD and SMTI?
According to the Medical Devices & Instruments industry distribution chart, OraSure Technologies ranks #110 out of 522 companies for Cyclically Adjusted PB Ratio. This places OraSure Technologies in the top 21% of its industry — outperforming the majority of peers. The industry median Cyclically Adjusted PB Ratio is 1.75. OraSure Technologies' value of 0.66 is 62.2% below this benchmark. Historically, OraSure Technologies' own Cyclically Adjusted PB Ratio has ranged from 0.40 to 7.76 over the past decade. While the company's 10-year median is 2.31 vs. the industry median of 1.75, OraSure Technologies has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Medical Devices & Instruments company?
The median Cyclically Adjusted PB Ratio among Medical Devices & Instruments companies is 1.75, based on 522 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. OraSure Technologies's current Cyclically Adjusted PB Ratio of 0.66 is 62.2% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on OraSure Technologies and its competitors. For the Medical Devices & Instruments industry, the median Cyclically Adjusted PB Ratio is 1.75 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. OraSure Technologies's current Cyclically Adjusted PB Ratio is 0.66, which is 71% below median its own 10-year median of 2.31. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is OraSure Technologies stock overvalued right now?
Based on GuruFocus' analysis, OraSure Technologies (OSUR) is currently considered Significantly Overvalued. The stock's GF Value™ is $1.99, compared to a current price of $3.79 — trading 90.2% above its estimated fair value. The current Cyclically Adjusted PB Ratio is 0.66, which is 71% below median its 10-year median of 2.31 and 62.2% below the Medical Devices & Instruments industry median of 1.75. OraSure Technologies' overall GF Score™ is 57/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For OraSure Technologies (OSUR), the current Cyclically Adjusted PB Ratio is 0.66 as of Jul. 22, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is OraSure Technologies (OSUR) Overvalued in 2026?

Based on GuruFocus' analysis, OraSure Technologies stock appears to be overvalued. The current stock price of $3.79 is trading 90.2% above its estimated GF Value™ of $1.99. GuruFocus considers OraSure Technologies to be Significantly Overvalued.

Key valuation signals for OSUR:

  • Cyclically Adjusted PB Ratio: 0.66 (71% below median its 10-year median of 2.31)
  • GF Value™: $1.99 vs. price of $3.79 (90.2% above fair value)
  • GF Score™: 57/100 with 3 warning signs
  • Industry Position: 62.2% below the Medical Devices & Instruments median (#110 of 522)

No single metric tells the full story. See the OSUR stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


OraSure Technologies Business Description

Other Exchanges EP3:Germany
Address 220 East First Street, Bethlehem, PA, USA, 18015
OraSure Technologies Inc is principally engaged in the development, manufacture, marketing, sale and distribution of (i) diagnostics products, and (ii) sample management solutions. It develops products and services that support diagnostic testing and healthcare data analysis, with a focus on improving access to healthcare. The company derives its revenues from the sale of diagnostics products and sample management solutions. Geographically, it generates the maximum revenue from the United States.
57GF Score

Get the complete analysis for OSUR

Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$3.79
Price
$1.99
GF Value