SCYX (SCYNEXIS) Cyclically Adjusted PB Ratio: 0.15 (As of Aug. 17, 2026) — Near Median

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

SCYX SCYNEXIS Inc SCYX
40 GF Score
Price $5.09
GF Value $17.37
Valuation Possible Value Trap
! 3 Warning Signs
View Full Analysis

What is SCYNEXIS Cyclically Adjusted PB Ratio?

SCYNEXIS SCYX -1.74% 40 Cyclically Adjusted PB Ratio is 0.15 as of Aug. 17, 2026, which is at its 10-year median of 0.15. GuruFocus rates SCYX with a GF Score™ of 40/100 and a GF Value™ of $17.37 (Possible Value Trap). The stock has 3 warning signs investors should review. Among 707 Drug Manufacturers companies, SCYNEXIS ranks better than 95.62% on this metric.

As of today (2026-08-17), SCYNEXIS's current share price is $5.09. SCYNEXIS's Cyclically Adjusted Book per Share for the quarter that ended in Jun. 2026 was $34.83. SCYNEXIS's Cyclically Adjusted PB Ratio for today is 0.15.

The historical rank and industry rank for SCYNEXIS's Cyclically Adjusted PB Ratio or its related term are showing as below:

SCYX' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 0.08   Med: 0.15   Max: 0.99
Current: 0.15

During the past years, SCYNEXIS's highest Cyclically Adjusted PB Ratio was 0.99. The lowest was 0.08. And the median was 0.15.

SCYX's Cyclically Adjusted PB Ratio is ranked better than
95.62% of 707 companies
in the Drug Manufacturers industry
Industry Median: 1.76 vs SCYX: 0.15

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

SCYNEXIS's adjusted book value per share data for the three months ended in Jun. 2026 was $6.727. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is $34.83 for the trailing ten years ended in Jun. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


SCYNEXIS  (NAS:SCYX) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


SCYNEXIS Cyclically Adjusted PB Ratio Related Terms


SCYNEXIS Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for SCYNEXIS's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

SCYNEXIS Cyclically Adjusted PB Ratio Chart

SCYNEXIS Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.29 0.23 0.12 0.11

SCYNEXIS Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.09 0.12 0.11 0.19 0.12

SCYX vs IXHL, ETST, INIS: Cyclically Adjusted PB Ratio Comparison

For the Drug Manufacturers - Specialty & Generic subindustry, SCYNEXIS's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


SCYNEXIS Cyclically Adjusted PB Ratio vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, SCYNEXIS's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where SCYNEXIS's Cyclically Adjusted PB Ratio falls into.


SCYX
40GF Score
SCYNEXIS Inc SCYX
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

SCYNEXIS Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

SCYNEXIS's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=5.09/34.83
=0.15

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

SCYNEXIS's Cyclically Adjusted Book per Share for the quarter that ended in Jun. 2026 is calculated as:

For example, SCYNEXIS's adjusted Book Value per Share data for the three months ended in Jun. 2026 was:

Adj_Book=Book Value per Share/CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=6.727/333.9520*333.9520
=6.727

Current CPI (Jun. 2026) = 333.9520.

SCYNEXIS Quarterly Data

Book Value per Share CPI Adj_Book
201609 113.229 241.428 156.622
201612 113.049 241.432 156.371
201703 105.119 243.801 143.989
201706 95.637 244.955 130.384
201709 77.017 246.819 104.206
201712 59.144 246.524 80.119
201803 62.874 249.554 84.138
201806 45.312 251.989 60.050
201809 47.253 252.439 62.511
201812 52.042 251.233 69.177
201903 18.041 254.202 23.701
201906 15.252 256.143 19.885
201909 8.568 256.759 11.144
201912 10.587 256.974 13.758
202003 5.278 258.115 6.829
202006 4.834 257.797 6.262
202009 7.080 260.280 9.084
202012 9.259 260.474 11.871
202103 10.056 264.877 12.678
202106 11.172 271.696 13.732
202109 12.597 274.310 15.336
202112 11.499 278.802 13.774
202203 10.656 287.504 12.378
202206 11.161 296.311 12.579
202209 4.216 296.808 4.744
202212 0.791 296.797 0.890
202303 -7.181 301.836 -7.945
202306 20.030 305.109 21.924
202309 19.796 307.789 21.479
202312 15.687 306.746 17.078
202403 15.694 312.332 16.780
202406 12.765 314.175 13.569
202409 12.340 315.301 13.070
202412 11.602 315.605 12.276
202503 10.359 319.799 10.817
202506 9.080 322.561 9.401
202509 6.946 324.800 7.142
202512 9.071 324.054 9.348
202603 5.326 330.213 5.386
202606 6.727 333.952 6.727

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 0.15 mean?
SCYNEXIS (SCYX) has a Cyclically Adjusted PB Ratio of 0.15 as of Aug. 17, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on SCYNEXIS and its competitors. This is near median its historical median of 0.15. Over the past decade, SCYNEXIS's Cyclically Adjusted PB Ratio has ranged from 0.08 to 0.99. According to the industry distribution chart, SCYNEXIS ranks #31 out of 707 companies in the Drug Manufacturers industry, placing it in the top 4.4%.
Is SCYNEXIS's Cyclically Adjusted PB Ratio too high?
SCYNEXIS's current Cyclically Adjusted PB Ratio of 0.15 is near median its 10-year median of 0.15. Over the past 10 years, this metric has ranged from a low of 0.08 to a high of 0.99. The Drug Manufacturers industry median Cyclically Adjusted PB Ratio is 1.76. SCYNEXIS's value of 0.15 is 91.5% below this industry median. Based on the distribution chart, SCYNEXIS ranks #31 out of 707 companies in the Drug Manufacturers industry, which is in the top quartile — a strong position relative to peers. Overall, SCYNEXIS has a GF Score™ of 40/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does SCYNEXIS's Cyclically Adjusted PB Ratio compare to IXHL and ETST?
According to the Drug Manufacturers industry distribution chart, SCYNEXIS ranks #31 out of 707 companies for Cyclically Adjusted PB Ratio. This places SCYNEXIS in the top 4% of its industry — outperforming the majority of peers. The industry median Cyclically Adjusted PB Ratio is 1.76. SCYNEXIS's value of 0.15 is 91.5% below this benchmark. Historically, SCYNEXIS's own Cyclically Adjusted PB Ratio has ranged from 0.08 to 0.99 over the past decade. While the company's 10-year median is 0.15 vs. the industry median of 1.76, SCYNEXIS has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Drug Manufacturers company?
The median Cyclically Adjusted PB Ratio among Drug Manufacturers companies is 1.76, based on 707 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. SCYNEXIS's current Cyclically Adjusted PB Ratio of 0.15 is 91.5% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on SCYNEXIS and its competitors. For the Drug Manufacturers industry, the median Cyclically Adjusted PB Ratio is 1.76 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. SCYNEXIS's current Cyclically Adjusted PB Ratio is 0.15, which is near median its own 10-year median of 0.15. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is SCYNEXIS stock overvalued right now?
Based on GuruFocus' analysis, SCYNEXIS (SCYX) is currently considered Possible Value Trap. The stock's GF Value™ is $17.37, compared to a current price of $5.09 — trading 70.7% below its estimated fair value. The current Cyclically Adjusted PB Ratio is 0.15, which is near median its 10-year median of 0.15 and 91.5% below the Drug Manufacturers industry median of 1.76. SCYNEXIS's overall GF Score™ is 40/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For SCYNEXIS (SCYX), the current Cyclically Adjusted PB Ratio is 0.15 as of Aug. 17, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is SCYNEXIS (SCYX) Overvalued in 2026?

Based on GuruFocus' analysis, SCYNEXIS stock appears to be undervalued. The current stock price of $5.09 is trading 70.7% below its estimated GF Value™ of $17.37. GuruFocus considers SCYNEXIS to be Possible Value Trap.

Key valuation signals for SCYX:

  • Cyclically Adjusted PB Ratio: 0.15 (near median its 10-year median of 0.15)
  • GF Value™: $17.37 vs. price of $5.09 (70.7% below fair value)
  • GF Score™: 40/100 with 3 warning signs
  • Industry Position: 91.5% below the Drug Manufacturers median (#31 of 707)

No single metric tells the full story. See the SCYX stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


SCYNEXIS Business Description

Other Exchanges 0L49:UK135:Germany
Address 1 Evertrust Plaza, 13th Floor, Jersey City, NJ, USA, 07302 - 6548
SCYNEXIS Inc is a drug development company that focuses on the development and commercialization of novel anti-infectives to address unmet therapeutic needs. It is engaged in developing a product candidate, ibrexafungerp which is a novel oral and intravenous (IV) drug for the treatment of several fungal infections, including serious and life-threatening invasive fungal infections. The ibrexafungerp is a novel and structurally distinct triterpenoid glucan synthase inhibitor that is effective in vitro and in vivo against broad range of Candida and Aspergillus species, including drug-resistant strains as well as Pneumocystis, Coccidioides, Histoplasma and Blastomyces genera and some common mucorales species.
40GF Score

Get the complete analysis for SCYX

Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$5.09
Price
$17.37
GF Value