Achieve Life Sciences (STU:SP4P) Cyclically Adjusted PB Ratio: 0.03 (As of Jul. 26, 2026) — 25% Below Median

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STU:SP4P Achieve Life Sciences Inc STU:SP4P
38 GF Score
Price €5.35
! 4 Warning Signs
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What is Achieve Life Sciences Cyclically Adjusted PB Ratio?

Achieve Life Sciences STU:SP4P -0.93% 38 Cyclically Adjusted PB Ratio is 0.03 as of Jul. 26, 2026, which is 25% below its 10-year median of 0.04. GuruFocus rates STU:SP4P with a GF Score™ of 38/100. The stock has 4 warning signs investors should review. Among 700 Biotechnology companies, Achieve Life Sciences ranks better than 96.43% on this metric.

As of today (2026-07-26), Achieve Life Sciences's current share price is €5.35. Achieve Life Sciences's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 was €191.48. Achieve Life Sciences's Cyclically Adjusted PB Ratio for today is 0.03.

The historical rank and industry rank for Achieve Life Sciences's Cyclically Adjusted PB Ratio or its related term are showing as below:

STU:SP4P' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 0.01   Med: 0.04   Max: 0.15
Current: 0.03

During the past years, Achieve Life Sciences's highest Cyclically Adjusted PB Ratio was 0.15. The lowest was 0.01. And the median was 0.04.

STU:SP4P's Cyclically Adjusted PB Ratio is ranked better than
96.43% of 700 companies
in the Biotechnology industry
Industry Median: 1.595 vs STU:SP4P: 0.03

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Achieve Life Sciences's adjusted book value per share data for the three months ended in Mar. 2026 was €0.173. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is €191.48 for the trailing ten years ended in Mar. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


Achieve Life Sciences  (STU:SP4P) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


Achieve Life Sciences Cyclically Adjusted PB Ratio Related Terms


Achieve Life Sciences Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for Achieve Life Sciences's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Achieve Life Sciences Cyclically Adjusted PB Ratio Chart

Achieve Life Sciences Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.00 0.01 0.02

Achieve Life Sciences Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 0.01 0.02 0.01

STU:SP4P vs STTK, CRMD, EIKN: Cyclically Adjusted PB Ratio Comparison

For the Biotechnology subindustry, Achieve Life Sciences's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Achieve Life Sciences Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Achieve Life Sciences's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Achieve Life Sciences's Cyclically Adjusted PB Ratio falls into.


STU:SP4P
38GF Score
Achieve Life Sciences Inc STU:SP4P
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
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Achieve Life Sciences Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

Achieve Life Sciences's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=5.35/191.48
=0.03

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Achieve Life Sciences's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 is calculated as:

For example, Achieve Life Sciences's adjusted Book Value per Share data for the three months ended in Mar. 2026 was:

Adj_Book=Book Value per Share/CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=0.173/330.2130*330.2130
=0.173

Current CPI (Mar. 2026) = 330.2130.

Achieve Life Sciences Quarterly Data

Book Value per Share CPI Adj_Book
201606 1,795.857 241.018 2,460.461
201609 1,554.071 241.428 2,125.580
201612 41.286 241.432 56.468
201703 1,061.286 243.801 1,437.445
201706 833.000 244.955 1,122.930
201709 157.228 246.819 210.351
201712 110.967 246.524 148.638
201803 77.828 249.554 102.983
201806 66.387 251.989 86.995
201809 49.547 252.439 64.812
201812 41.339 251.233 54.335
201903 26.836 254.202 34.860
201906 25.138 256.143 32.407
201909 18.252 256.759 23.474
201912 11.021 256.974 14.162
202003 8.649 258.115 11.065
202006 6.662 257.797 8.533
202009 6.028 260.280 7.648
202012 5.015 260.474 6.358
202103 4.110 264.877 5.124
202106 3.587 271.696 4.360
202109 3.120 274.310 3.756
202112 2.625 278.802 3.109
202203 2.054 287.504 2.359
202206 1.286 296.311 1.433
202209 0.109 296.808 0.121
202212 0.438 296.797 0.487
202303 0.023 301.836 0.025
202306 0.424 305.109 0.459
202309 0.179 307.789 0.192
202312 -0.063 306.746 -0.068
202403 1.328 312.332 1.404
202406 1.144 314.175 1.202
202409 0.822 315.301 0.861
202412 0.575 315.605 0.602
202503 0.274 319.799 0.283
202506 0.727 322.561 0.744
202509 0.542 324.800 0.551
202512 0.345 324.054 0.352
202603 0.173 330.213 0.173

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 0.03 mean?
Achieve Life Sciences (STU:SP4P) has a Cyclically Adjusted PB Ratio of 0.03 as of Jul. 26, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Achieve Life Sciences and its competitors. This is 25% below median its historical median of 0.04. Over the past decade, Achieve Life Sciences' Cyclically Adjusted PB Ratio has ranged from 0.01 to 0.15. According to the industry distribution chart, Achieve Life Sciences ranks #25 out of 700 companies in the Biotechnology industry, placing it in the top 3.6%.
Is Achieve Life Sciences' Cyclically Adjusted PB Ratio too high?
Achieve Life Sciences' current Cyclically Adjusted PB Ratio of 0.03 is 25% below median its 10-year median of 0.04. Over the past 10 years, this metric has ranged from a low of 0.01 to a high of 0.15. The Biotechnology industry median Cyclically Adjusted PB Ratio is 1.60. Achieve Life Sciences' value of 0.03 is 98.1% below this industry median. Based on the distribution chart, Achieve Life Sciences ranks #25 out of 700 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Achieve Life Sciences has a GF Score™ of 38/100, reflecting its overall financial health beyond just this single metric.
How does Achieve Life Sciences' Cyclically Adjusted PB Ratio compare to STTK and CRMD?
According to the Biotechnology industry distribution chart, Achieve Life Sciences ranks #25 out of 700 companies for Cyclically Adjusted PB Ratio. This places Achieve Life Sciences in the top 4% of its industry — outperforming the majority of peers. The industry median Cyclically Adjusted PB Ratio is 1.60. Achieve Life Sciences' value of 0.03 is 98.1% below this benchmark. Historically, Achieve Life Sciences' own Cyclically Adjusted PB Ratio has ranged from 0.01 to 0.15 over the past decade. While the company's 10-year median is 0.04 vs. the industry median of 1.60, Achieve Life Sciences has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Biotechnology company?
The median Cyclically Adjusted PB Ratio among Biotechnology companies is 1.60, based on 700 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Achieve Life Sciences's current Cyclically Adjusted PB Ratio of 0.03 is 98.1% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Achieve Life Sciences and its competitors. For the Biotechnology industry, the median Cyclically Adjusted PB Ratio is 1.60 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Achieve Life Sciences's current Cyclically Adjusted PB Ratio is 0.03, which is 25% below median its own 10-year median of 0.04. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Achieve Life Sciences stock overvalued right now?
Achieve Life Sciences (STU:SP4P) has a current Cyclically Adjusted PB Ratio of 0.03. The current Cyclically Adjusted PB Ratio is 0.03, which is 25% below median its 10-year median of 0.04 and 98.1% below the Biotechnology industry median of 1.60. Achieve Life Sciences' overall GF Score™ is 38/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Achieve Life Sciences (STU:SP4P), the current Cyclically Adjusted PB Ratio is 0.03 as of Jul. 26, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Achieve Life Sciences Business Description

Other Exchanges ACHV:USASP4P:Germany
Address 22722 29th Drive SE, Suite 100, Bothell, WA, USA, 98021
Achieve Life Sciences Inc is a late-stage clinical specialty pharmaceutical company with the sole mission to address the nicotine dependence epidemic through the development and commercialization of cytisinicline. Cytisinicline, is a naturally occurring alkaloid. Additionally, The company has completed a Phase 2 study with cytisinicline in vaping cessation and conducted a successful end-of-Phase 2 meeting with the FDA for a future vaping indication. It operates in one operating segment, development and commercialization of cytisinicline for nicotine dependence, with operations located in Canada, the United States and the U.K.
38GF Score

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