Tanvex BioPharma (TPE:6541) Cyclically Adjusted PB Ratio: 1.20 (As of Jul. 28, 2026) — 26% Below Median

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

TPE:6541 Tanvex BioPharma Inc TPE:6541
44 GF Score
Price NT$38.40
! 4 Warning Signs
View Full Analysis

What is Tanvex BioPharma Cyclically Adjusted PB Ratio?

Tanvex BioPharma TPE:6541 -2.78% 44 Cyclically Adjusted PB Ratio is 1.20 as of Jul. 28, 2026, which is 26% below its 10-year median of 1.63. GuruFocus rates TPE:6541 with a GF Score™ of 44/100. The stock has 4 warning signs investors should review. Among 698 Biotechnology companies, Tanvex BioPharma ranks better than 57.16% on this metric.

As of today (2026-07-28), Tanvex BioPharma's current share price is NT$38.40. Tanvex BioPharma's Cyclically Adjusted Book per Share for the quarter that ended in Dec. 2025 was NT$32.10. Tanvex BioPharma's Cyclically Adjusted PB Ratio for today is 1.20.

The historical rank and industry rank for Tanvex BioPharma's Cyclically Adjusted PB Ratio or its related term are showing as below:

TPE:6541' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 1.19   Med: 1.63   Max: 2.47
Current: 1.2

During the past years, Tanvex BioPharma's highest Cyclically Adjusted PB Ratio was 2.47. The lowest was 1.19. And the median was 1.63.

TPE:6541's Cyclically Adjusted PB Ratio is ranked better than
57.16% of 698 companies
in the Biotechnology industry
Industry Median: 1.62 vs TPE:6541: 1.20

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Tanvex BioPharma's adjusted book value per share data for the three months ended in Dec. 2025 was NT$21.498. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is NT$32.10 for the trailing ten years ended in Dec. 2025.

Shiller PE for Stocks: The True Measure of Stock Valuation


Tanvex BioPharma  (TPE:6541) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


Tanvex BioPharma Cyclically Adjusted PB Ratio Related Terms


Tanvex BioPharma Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for Tanvex BioPharma's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Tanvex BioPharma Cyclically Adjusted PB Ratio Chart

Tanvex BioPharma Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.00 2.06 1.71

Tanvex BioPharma Quarterly Data
Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 2.06 1.94 1.60 1.59 1.71

TPE:6541 vs VRTX, REGN, RVMD: Cyclically Adjusted PB Ratio Comparison

For the Biotechnology subindustry, Tanvex BioPharma's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Tanvex BioPharma Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Tanvex BioPharma's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Tanvex BioPharma's Cyclically Adjusted PB Ratio falls into.


TPE:6541
44GF Score
Tanvex BioPharma Inc TPE:6541
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Tanvex BioPharma Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

Tanvex BioPharma's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=38.40/32.10
=1.20

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Tanvex BioPharma's Cyclically Adjusted Book per Share for the quarter that ended in Dec. 2025 is calculated as:

For example, Tanvex BioPharma's adjusted Book Value per Share data for the three months ended in Dec. 2025 was:

Adj_Book=Book Value per Share/CPI of Dec. 2025 (Change)*Current CPI (Dec. 2025)
=21.498/324.0540*324.0540
=21.498

Current CPI (Dec. 2025) = 324.0540.

Tanvex BioPharma Quarterly Data

Book Value per Share CPI Adj_Book
201603 0.000 238.132 0.000
201606 60.622 241.018 81.508
201609 0.000 241.428 0.000
201612 51.064 241.432 68.539
201703 44.042 243.801 58.539
201706 39.770 244.955 52.612
201709 35.893 246.819 47.125
201712 47.733 246.524 62.745
201803 43.177 249.554 56.067
201806 37.422 251.989 48.124
201809 52.944 252.439 67.964
201812 48.262 251.233 62.251
201903 43.016 254.202 54.836
201906 37.649 256.143 47.631
201909 30.461 256.759 38.445
201912 32.139 256.974 40.529
202003 26.126 258.115 32.800
202006 19.675 257.797 24.732
202009 15.039 260.280 18.724
202012 24.049 260.474 29.919
202103 20.619 264.877 25.226
202106 16.904 271.696 20.162
202109 25.659 274.310 30.312
202112 22.886 278.802 26.601
202203 20.404 287.504 22.998
202206 17.720 296.311 19.379
202209 15.452 296.808 16.870
202212 11.388 296.797 12.434
202303 8.338 301.836 8.952
202306 13.160 305.109 13.977
202309 10.060 307.789 10.592
202312 6.021 306.746 6.361
202403 3.004 312.332 3.117
202406 8.935 314.175 9.216
202409 6.941 315.301 7.134
202412 5.400 315.605 5.545
202503 23.065 319.799 23.372
202506 20.253 322.561 20.347
202509 22.663 324.800 22.611
202512 21.498 324.054 21.498

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 1.20 mean?
Tanvex BioPharma (TPE:6541) has a Cyclically Adjusted PB Ratio of 1.20 as of Jul. 28, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Tanvex BioPharma and its competitors. This is 26% below median its historical median of 1.63. Over the past decade, Tanvex BioPharma's Cyclically Adjusted PB Ratio has ranged from 1.19 to 2.47. According to the industry distribution chart, Tanvex BioPharma ranks #299 out of 698 companies in the Biotechnology industry, placing it in the top 42.8%.
Is Tanvex BioPharma's Cyclically Adjusted PB Ratio too high?
Tanvex BioPharma's current Cyclically Adjusted PB Ratio of 1.20 is 26% below median its 10-year median of 1.63. Over the past 10 years, this metric has ranged from a low of 1.19 to a high of 2.47. The Biotechnology industry median Cyclically Adjusted PB Ratio is 1.62. Tanvex BioPharma's value of 1.20 is 25.9% below this industry median. Based on the distribution chart, Tanvex BioPharma ranks #299 out of 698 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Tanvex BioPharma has a GF Score™ of 44/100, reflecting its overall financial health beyond just this single metric.
How does Tanvex BioPharma's Cyclically Adjusted PB Ratio compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Tanvex BioPharma ranks #299 out of 698 companies for Cyclically Adjusted PB Ratio. This puts Tanvex BioPharma in the upper half of its industry. The industry median Cyclically Adjusted PB Ratio is 1.62. Tanvex BioPharma's value of 1.20 is 25.9% below this benchmark. Historically, Tanvex BioPharma's own Cyclically Adjusted PB Ratio has ranged from 1.19 to 2.47 over the past decade. While the company's 10-year median is 1.63 vs. the industry median of 1.62, Tanvex BioPharma has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Biotechnology company?
The median Cyclically Adjusted PB Ratio among Biotechnology companies is 1.62, based on 698 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Tanvex BioPharma's current Cyclically Adjusted PB Ratio of 1.20 is 25.9% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Tanvex BioPharma and its competitors. For the Biotechnology industry, the median Cyclically Adjusted PB Ratio is 1.62 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Tanvex BioPharma's current Cyclically Adjusted PB Ratio is 1.20, which is 26% below median its own 10-year median of 1.63. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Tanvex BioPharma stock overvalued right now?
Tanvex BioPharma (TPE:6541) has a current Cyclically Adjusted PB Ratio of 1.20. The current Cyclically Adjusted PB Ratio is 1.20, which is 26% below median its 10-year median of 1.63 and 25.9% below the Biotechnology industry median of 1.62. Tanvex BioPharma's overall GF Score™ is 44/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Tanvex BioPharma (TPE:6541), the current Cyclically Adjusted PB Ratio is 1.20 as of Jul. 28, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Tanvex BioPharma Business Description

Address No. 12-2, Shengyi Road, Section 2, 6th Floor, Hsinchu County, Zhubei, TWN, 106
Tanvex BioPharma Inc is a biopharmaceutical company. It is engaged in the research, development, manufacture, and sale of biosimilar products and contract development and manufacturing of biological medicine. The company's products are used to cure diseases such as Neutropenia, Breast Cancer, Metastatic Colorectal Cancer, and others. Geographically, the company operates in Asia, America, Europe, and Australia. The company generates a majority of its revenue from the USA.
44GF Score

Get the complete analysis for TPE:6541

Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

NT$38.40
Price