Tanvex BioPharma (TPE:6541) Operating Margin %: -201.86% (As of Dec. 2025)


TPE:6541 Tanvex BioPharma Inc TPE:6541
57 GF Score
Price NT$41.40
GF Value NT$254.61
Valuation Possible Value Trap
! 4 Warning Signs
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What is Tanvex BioPharma Operating Margin %?

Tanvex BioPharma TPE:6541 +2.10% 57 Operating Margin % is -201.86% as of Dec. 2025. GuruFocus rates TPE:6541 with a GF Score™ of 57/100 and a GF Value™ of NT$254.61 (Possible Value Trap). The stock has 4 warning signs investors should review. Among 938 Biotechnology companies, Tanvex BioPharma ranks worse than 65.99% on this metric.

Operating Margin % is calculated as Operating Income divided by its Revenue. Tanvex BioPharma's Operating Income for the three months ended in Dec. 2025 was NT$-361.2 Mil. Tanvex BioPharma's Revenue for the three months ended in Dec. 2025 was NT$179.0 Mil. Therefore, Tanvex BioPharma's Operating Margin % for the quarter that ended in Dec. 2025 was -201.86%.

Good Sign:

Tanvex BioPharma Inc operating margin is expanding. Margin expansion is usually a good sign.

The historical rank and industry rank for Tanvex BioPharma's Operating Margin % or its related term are showing as below:

TPE:6541' s Operating Margin % Range Over the Past 10 Years
Min: -699859   Med: -5539.31   Max: -344.59
Current: -344.59


TPE:6541's Operating Margin % is ranked worse than
65.99% of 938 companies
in the Biotechnology industry
Industry Median: -86.55 vs TPE:6541: -344.59

Tanvex BioPharma's 5-Year Average Operating Margin % Growth Rate was 72.30% per year.

Tanvex BioPharma's Operating Income for the three months ended in Dec. 2025 was NT$-361.2 Mil. Its Operating Income for the trailing twelve months (TTM) ended in Dec. 2025 was NT$-1,381.7 Mil.


Tanvex BioPharma  (TPE:6541) Operating Margin % Explanation

Just like Gross Margin %, it is important to see a company maintains its operating margin over time. Among the same industry, a company with higher operating margin is more efficient in its operation. It is also more stable during industry slowdown or recessions. Peter Lynch prefers those with higher margins than those with lower margins.


Be Aware

Operating Margin % can be manipulated by adjusting the rate of depreciation, depletion and amortization (DDA).

If a company is facing competition, its Operating Margin % may decline. Often the Operating Margin % declines well before the company's Revenue or even profit decline. Therefore, Operating Margin % is a very important indicator of whether the company is facing problems.

For instance, by 2012, Nokia (NOK)'s problems were well known and its stock had lost more than 90% of its market value since 2007. But Nokia’s Operating Margin % had already been in decline since 2002, although its Earnings per Share (Diluted) were still rising. Investors who paid attention to Operating Margin % would have avoided this huge loss. The same can be said for Research-in-Motion (RIMM).

Therefore, Operating Margin % is a very important screening filter for GuruFocus. GuruFocus's Buffett-Munger screener requires that the profit margin is either consistent or expanding. The Model Portfolio of the Buffett-Munger screener has outperformed the market every year since inception in 2009.


Tanvex BioPharma Operating Margin % Related Terms


Tanvex BioPharma Operating Margin % Historical Data

* Premium members only.

The historical data trend for Tanvex BioPharma's Operating Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Tanvex BioPharma Operating Margin % Chart

Tanvex BioPharma Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Operating Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -29,581.65 -7,166.21 -3,420.80 -3,912.40 -344.59

Tanvex BioPharma Quarterly Data
Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25
Operating Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -9,872.85 -794.89 -721.92 -228.30 -201.86

TPE:6541 vs VRTX, REGN, ALNY: Operating Margin % Comparison

For the Biotechnology subindustry, Tanvex BioPharma's Operating Margin %, along with its competitors' market caps and Operating Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Tanvex BioPharma Operating Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Tanvex BioPharma's Operating Margin % distribution charts can be found below:

* The bar in red indicates where Tanvex BioPharma's Operating Margin % falls into.


TPE:6541
57GF Score
Tanvex BioPharma Inc TPE:6541
Operating Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Tanvex BioPharma Operating Margin % Calculation

Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.

Tanvex BioPharma's Operating Margin % for the fiscal year that ended in Dec. 2025 is calculated as

Operating Margin %=Operating Income (A: Dec. 2025 ) / Revenue (A: Dec. 2025 )
=-1381.716 / 400.971
=-344.59 %

Tanvex BioPharma's Operating Margin % for the quarter that ended in Dec. 2025 is calculated as

Operating Margin %=Operating Income (Q: Dec. 2025 ) / Revenue (Q: Dec. 2025 )
=-361.227 / 178.953
=-201.86 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Operating Margin % →
What does a Operating Margin % of -201.86% mean?
Tanvex BioPharma (TPE:6541) has a Operating Margin % of -201.86% as of Dec. 2025. Operating margin is the ratio of total operating income to net sales. View historical data on Tanvex BioPharma and its competitors. According to the industry distribution chart, Tanvex BioPharma ranks #619 out of 938 companies in the Biotechnology industry, placing it in the top 66%.
Is Tanvex BioPharma's Operating Margin % too high?
Tanvex BioPharma's current Operating Margin % is -201.86%. Based on the distribution chart, Tanvex BioPharma ranks #619 out of 938 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Tanvex BioPharma has a GF Score™ of 57/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does Tanvex BioPharma's Operating Margin % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Tanvex BioPharma ranks #619 out of 938 companies for Operating Margin %. This places Tanvex BioPharma in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Operating Margin % for a Biotechnology company?
A good Operating Margin % depends on the Biotechnology industry context. However, Operating Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Operating Margin % mean?
A high Operating Margin % can signal that a stock is expensive relative to its fundamentals. Operating margin is the ratio of total operating income to net sales. View historical data on Tanvex BioPharma and its competitors. Tanvex BioPharma's current Operating Margin % is -201.86%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Tanvex BioPharma stock overvalued right now?
Based on GuruFocus' analysis, Tanvex BioPharma (TPE:6541) is currently considered Possible Value Trap. The stock's GF Value™ is NT$254.61, compared to a current price of NT$41.40 — trading 83.7% below its estimated fair value. The current Operating Margin % is -201.86%. Tanvex BioPharma's overall GF Score™ is 57/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Operating Margin % calculated?
Operating Margin % is calculated from a company's financial statements. For Tanvex BioPharma (TPE:6541), the current Operating Margin % is -201.86% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Tanvex BioPharma (TPE:6541) Overvalued in 2026?

Based on GuruFocus' analysis, Tanvex BioPharma stock appears to be undervalued. The current stock price of NT$41.40 is trading 83.7% below its estimated GF Value™ of NT$254.61. GuruFocus considers Tanvex BioPharma to be Possible Value Trap.

Key valuation signals for TPE:6541:

  • Operating Margin %: -201.86%
  • GF Value™: NT$254.61 vs. price of NT$41.40 (83.7% below fair value)
  • GF Score™: 57/100 with 4 warning signs

No single metric tells the full story. See the TPE:6541 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Tanvex BioPharma Business Description

Address No. 12-2, Shengyi Road, Section 2, 6th Floor, Hsinchu County, Zhubei, TWN, 106
Tanvex BioPharma Inc is a biopharmaceutical company. It is engaged in the research, development, manufacture, and sale of biosimilar products and contract development and manufacturing of biological medicine. The company's products are used to cure diseases such as Neutropenia, Breast Cancer, Metastatic Colorectal Cancer, and others. Geographically, the company operates in Asia, America, Europe, and Australia. The company generates a majority of its revenue from the USA.
57GF Score

Get the complete analysis for TPE:6541

Operating Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

NT$41.40
Price
NT$254.61
GF Value