Seikagaku (TSE:4548) Cyclically Adjusted PB Ratio: 0.53 (As of Aug. 05, 2026) — 32% Below Median

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TSE:4548 Seikagaku Corp TSE:4548
73 GF Score
Price 円727.00
GF Value 円777.41
Valuation Fairly Valued
! 6 Warning Signs
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What is Seikagaku Cyclically Adjusted PB Ratio?

Seikagaku TSE:4548 73 Cyclically Adjusted PB Ratio is 0.53 as of Aug. 05, 2026, which is 32% below its 10-year median of 0.78. GuruFocus rates TSE:4548 with a GF Score™ of 73/100 and a GF Value™ of 円777.41 (Fairly Valued). The stock has 6 warning signs investors should review. Among 521 Medical Devices & Instruments companies, Seikagaku ranks better than 81.77% on this metric.

As of today (2026-08-05), Seikagaku's current share price is 円727.00. Seikagaku's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 was 円1,371.75. Seikagaku's Cyclically Adjusted PB Ratio for today is 0.53.

The historical rank and industry rank for Seikagaku's Cyclically Adjusted PB Ratio or its related term are showing as below:

TSE:4548' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 0.45   Med: 0.78   Max: 1.92
Current: 0.55

During the past years, Seikagaku's highest Cyclically Adjusted PB Ratio was 1.92. The lowest was 0.45. And the median was 0.78.

TSE:4548's Cyclically Adjusted PB Ratio is ranked better than
81.77% of 521 companies
in the Medical Devices & Instruments industry
Industry Median: 1.77 vs TSE:4548: 0.55

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Seikagaku's adjusted book value per share data for the three months ended in Mar. 2026 was 円1,379.008. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is 円1,371.75 for the trailing ten years ended in Mar. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


Seikagaku  (TSE:4548) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


Seikagaku Cyclically Adjusted PB Ratio Related Terms


Seikagaku Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for Seikagaku's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Seikagaku Cyclically Adjusted PB Ratio Chart

Seikagaku Annual Data
Trend Mar17 Mar18 Mar19 Mar20 Mar21 Mar22 Mar23 Mar24 Mar25 Mar26
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.72 0.64 0.58 0.54 0.53

Seikagaku Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.54 0.45 0.49 0.52 0.53

TSE:4548 vs ABT, SYK, MDT: Cyclically Adjusted PB Ratio Comparison

For the Medical Devices subindustry, Seikagaku's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Seikagaku Cyclically Adjusted PB Ratio vs Medical Devices & Instruments Industry

For the Medical Devices & Instruments industry and Healthcare sector, Seikagaku's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Seikagaku's Cyclically Adjusted PB Ratio falls into.


TSE:4548
73GF Score
Seikagaku Corp TSE:4548
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Seikagaku Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

Seikagaku's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=727.00/1371.75
=0.53

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Seikagaku's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 is calculated as:

For example, Seikagaku's adjusted Book Value per Share data for the three months ended in Mar. 2026 was:

Adj_Book=Book Value per Share/CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=1379.008/112.7000*112.7000
=1,379.008

Current CPI (Mar. 2026) = 112.7000.

Seikagaku Quarterly Data

Book Value per Share CPI Adj_Book
201606 1,245.716 98.100 1,431.113
201609 1,245.771 98.000 1,432.637
201612 1,260.925 98.400 1,444.169
201703 1,248.017 98.100 1,433.757
201706 1,246.215 98.500 1,425.872
201709 1,301.846 98.800 1,485.000
201712 1,315.908 99.400 1,491.980
201803 1,306.339 99.200 1,484.117
201806 1,302.022 99.200 1,479.212
201809 1,322.388 99.900 1,491.823
201812 1,291.788 99.700 1,460.226
201903 1,294.855 99.700 1,463.693
201906 1,295.795 99.800 1,463.288
201909 1,087.831 100.100 1,224.761
201912 1,108.077 100.500 1,242.590
202003 1,059.363 100.300 1,190.331
202006 1,063.351 99.900 1,199.596
202009 1,072.072 99.900 1,209.435
202012 1,068.243 99.300 1,212.397
202103 1,127.113 99.900 1,271.528
202106 1,197.696 99.500 1,356.586
202109 1,219.617 100.100 1,373.135
202112 1,203.810 100.100 1,355.339
202203 1,179.426 101.100 1,314.751
202206 1,206.151 101.800 1,335.297
202209 1,264.562 103.100 1,382.310
202212 1,279.148 104.100 1,384.822
202303 1,232.394 104.400 1,330.372
202306 1,275.279 105.200 1,366.197
202309 1,311.729 106.200 1,392.014
202312 1,314.479 106.800 1,387.095
202403 1,324.798 107.200 1,392.768
202406 1,369.685 108.200 1,426.650
202409 1,379.475 108.900 1,427.611
202412 1,354.887 110.700 1,379.366
202503 1,340.925 111.100 1,360.236
202506 1,312.415 111.700 1,324.164
202509 1,323.041 112.000 1,331.310
202512 1,337.143 113.000 1,333.593
202603 1,379.008 112.700 1,379.008

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 0.53 mean?
Seikagaku (TSE:4548) has a Cyclically Adjusted PB Ratio of 0.53 as of Aug. 05, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Seikagaku and its competitors. This is 32% below median its historical median of 0.78. Over the past decade, Seikagaku's Cyclically Adjusted PB Ratio has ranged from 0.45 to 1.92. According to the industry distribution chart, Seikagaku ranks #95 out of 521 companies in the Medical Devices & Instruments industry, placing it in the top 18.2%.
Is Seikagaku's Cyclically Adjusted PB Ratio too high?
Seikagaku's current Cyclically Adjusted PB Ratio of 0.53 is 32% below median its 10-year median of 0.78. Over the past 10 years, this metric has ranged from a low of 0.45 to a high of 1.92. The Medical Devices & Instruments industry median Cyclically Adjusted PB Ratio is 1.77. Seikagaku's value of 0.53 is 70.1% below this industry median. Based on the distribution chart, Seikagaku ranks #95 out of 521 companies in the Medical Devices & Instruments industry, which is in the top quartile — a strong position relative to peers. Overall, Seikagaku has a GF Score™ of 73/100 and is considered Fairly Valued, reflecting its overall financial health beyond just this single metric.
How does Seikagaku's Cyclically Adjusted PB Ratio compare to ABT and SYK?
According to the Medical Devices & Instruments industry distribution chart, Seikagaku ranks #95 out of 521 companies for Cyclically Adjusted PB Ratio. This places Seikagaku in the top 18% of its industry — outperforming the majority of peers. The industry median Cyclically Adjusted PB Ratio is 1.77. Seikagaku's value of 0.53 is 70.1% below this benchmark. Historically, Seikagaku's own Cyclically Adjusted PB Ratio has ranged from 0.45 to 1.92 over the past decade. While the company's 10-year median is 0.78 vs. the industry median of 1.77, Seikagaku has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Medical Devices & Instruments company?
The median Cyclically Adjusted PB Ratio among Medical Devices & Instruments companies is 1.77, based on 521 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Seikagaku's current Cyclically Adjusted PB Ratio of 0.53 is 70.1% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Seikagaku and its competitors. For the Medical Devices & Instruments industry, the median Cyclically Adjusted PB Ratio is 1.77 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Seikagaku's current Cyclically Adjusted PB Ratio is 0.53, which is 32% below median its own 10-year median of 0.78. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Seikagaku stock overvalued right now?
Based on GuruFocus' analysis, Seikagaku (TSE:4548) is currently considered Fairly Valued. The stock's GF Value™ is 円777.41, compared to a current price of 円727.00 — trading 6.5% below its estimated fair value. The current Cyclically Adjusted PB Ratio is 0.53, which is 32% below median its 10-year median of 0.78 and 70.1% below the Medical Devices & Instruments industry median of 1.77. Seikagaku's overall GF Score™ is 73/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Seikagaku (TSE:4548), the current Cyclically Adjusted PB Ratio is 0.53 as of Aug. 05, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Seikagaku (TSE:4548) Overvalued in 2026?

Based on GuruFocus' analysis, Seikagaku stock appears to be undervalued. The current stock price of 円727.00 is trading 6.5% below its estimated GF Value™ of 円777.41. GuruFocus considers Seikagaku to be Fairly Valued.

Key valuation signals for TSE:4548:

  • Cyclically Adjusted PB Ratio: 0.53 (32% below median its 10-year median of 0.78)
  • GF Value™: 円777.41 vs. price of 円727.00 (6.5% below fair value)
  • GF Score™: 73/100 with 6 warning signs
  • Industry Position: 70.1% below the Medical Devices & Instruments median (#95 of 521)

No single metric tells the full story. See the TSE:4548 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Seikagaku Business Description

Other Exchanges SKUNF:USA
Address Marunouchi Center Building 10 Floor, 6-1, Marunouchi 1-chome, Chiyoda-ku, Tokyo, JPN, 100-0005
Seikagaku Corp makes and sells pharmaceuticals and medical devices related to glycoconjugates. The firm operates in two segments: pharmaceutical and LAL. The pharmaceutical segment contributes the majority of revenue. This business sells pharmaceutical products made from hyaluronic acid, a major component of glycoconjugates, as well as medical devices and bulk products. The LAL segment manufactures endotoxin-detecting reagents made from limulus amebocyte lysate that are used to control quality in the pharmaceutical manufacturing process. Seikagaku generates the majority of its sales in Japan.
73GF Score

Get the complete analysis for TSE:4548

Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

円727.00
Price
円777.41
GF Value