HLS Therapeutics (TSX:HLS) Cyclically Adjusted PB Ratio: 0.68 (As of Jul. 14, 2026) — 51% Below Median

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TSX:HLS HLS Therapeutics Inc TSX:HLS
66 GF Score
Price C$4.23
GF Value C$4.51
Valuation Fairly Valued
! 4 Warning Signs
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What is HLS Therapeutics Cyclically Adjusted PB Ratio?

HLS Therapeutics TSX:HLS -1.86% 66 Cyclically Adjusted PB Ratio is 0.68 as of Jul. 14, 2026, which is 51% below its 10-year median of 1.39. GuruFocus rates TSX:HLS with a GF Score™ of 66/100 and a GF Value™ of C$4.51 (Fairly Valued). The stock has 4 warning signs investors should review. Among 759 Drug Manufacturers companies, HLS Therapeutics ranks better than 82.61% on this metric.

As of today (2026-07-14), HLS Therapeutics's current share price is C$4.23. HLS Therapeutics's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 was C$6.24. HLS Therapeutics's Cyclically Adjusted PB Ratio for today is 0.68.

The historical rank and industry rank for HLS Therapeutics's Cyclically Adjusted PB Ratio or its related term are showing as below:

TSX:HLS' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 0.51   Med: 1.39   Max: 6.48
Current: 0.69

During the past years, HLS Therapeutics's highest Cyclically Adjusted PB Ratio was 6.48. The lowest was 0.51. And the median was 1.39.

TSX:HLS's Cyclically Adjusted PB Ratio is ranked better than
82.61% of 759 companies
in the Drug Manufacturers industry
Industry Median: 1.82 vs TSX:HLS: 0.69

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

HLS Therapeutics's adjusted book value per share data for the three months ended in Mar. 2026 was C$2.569. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is C$6.24 for the trailing ten years ended in Mar. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


HLS Therapeutics  (TSX:HLS) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


HLS Therapeutics Cyclically Adjusted PB Ratio Related Terms


HLS Therapeutics Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for HLS Therapeutics's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

HLS Therapeutics Cyclically Adjusted PB Ratio Chart

HLS Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 3.03 1.76 0.66 0.64 0.78

HLS Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.75 0.78 0.92 0.78 0.70

TSX:HLS vs ZTS, UTHR: Cyclically Adjusted PB Ratio Comparison

For the Drug Manufacturers - Specialty & Generic subindustry, HLS Therapeutics's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


HLS Therapeutics Cyclically Adjusted PB Ratio vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, HLS Therapeutics's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where HLS Therapeutics's Cyclically Adjusted PB Ratio falls into.


TSX:HLS
66GF Score
HLS Therapeutics Inc TSX:HLS
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

HLS Therapeutics Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

HLS Therapeutics's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=4.23/6.24
=0.68

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

HLS Therapeutics's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 is calculated as:

For example, HLS Therapeutics's adjusted Book Value per Share data for the three months ended in Mar. 2026 was:

Adj_Book=Book Value per Share/CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=2.569/132.2623*132.2623
=2.569

Current CPI (Mar. 2026) = 132.2623.

HLS Therapeutics Quarterly Data

Book Value per Share CPI Adj_Book
201606 2.616 102.002 3.392
201609 2.608 101.765 3.390
201612 2.566 101.449 3.345
201703 2.568 102.634 3.309
201706 2.590 103.029 3.325
201709 2.478 103.345 3.171
201712 8.397 103.345 10.747
201803 8.945 105.004 11.267
201806 8.840 105.557 11.076
201809 7.968 105.636 9.976
201812 7.802 105.399 9.791
201903 7.689 106.979 9.506
201906 8.346 107.690 10.250
201909 8.121 107.611 9.981
201912 7.556 107.769 9.273
202003 7.395 107.927 9.062
202006 7.197 108.401 8.781
202009 7.037 108.164 8.605
202012 6.813 108.559 8.301
202103 6.614 110.298 7.931
202106 6.436 111.720 7.619
202109 6.436 112.905 7.539
202112 6.340 113.774 7.370
202203 6.201 117.646 6.971
202206 5.704 120.806 6.245
202209 5.410 120.648 5.931
202212 5.262 120.964 5.753
202303 5.029 122.702 5.421
202306 4.584 124.203 4.881
202309 4.283 125.230 4.523
202312 4.098 125.072 4.334
202403 3.781 126.258 3.961
202406 3.565 127.522 3.698
202409 3.380 127.285 3.512
202412 3.197 127.364 3.320
202503 3.022 129.181 3.094
202506 2.889 129.892 2.942
202509 2.731 130.287 2.772
202512 2.720 130.366 2.760
202603 2.569 132.262 2.569

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 0.68 mean?
HLS Therapeutics (TSX:HLS) has a Cyclically Adjusted PB Ratio of 0.68 as of Jul. 14, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on HLS Therapeutics and its competitors. This is 51% below median its historical median of 1.39. Over the past decade, HLS Therapeutics' Cyclically Adjusted PB Ratio has ranged from 0.51 to 6.48. According to the industry distribution chart, HLS Therapeutics ranks #132 out of 759 companies in the Drug Manufacturers industry, placing it in the top 17.4%.
Is HLS Therapeutics' Cyclically Adjusted PB Ratio too high?
HLS Therapeutics' current Cyclically Adjusted PB Ratio of 0.68 is 51% below median its 10-year median of 1.39. Over the past 10 years, this metric has ranged from a low of 0.51 to a high of 6.48. The Drug Manufacturers industry median Cyclically Adjusted PB Ratio is 1.82. HLS Therapeutics' value of 0.68 is 62.6% below this industry median. Based on the distribution chart, HLS Therapeutics ranks #132 out of 759 companies in the Drug Manufacturers industry, which is in the top quartile — a strong position relative to peers. Overall, HLS Therapeutics has a GF Score™ of 66/100 and is considered Fairly Valued, reflecting its overall financial health beyond just this single metric.
How does HLS Therapeutics' Cyclically Adjusted PB Ratio compare to ZTS and UTHR?
According to the Drug Manufacturers industry distribution chart, HLS Therapeutics ranks #132 out of 759 companies for Cyclically Adjusted PB Ratio. This places HLS Therapeutics in the top 17% of its industry — outperforming the majority of peers. The industry median Cyclically Adjusted PB Ratio is 1.82. HLS Therapeutics' value of 0.68 is 62.6% below this benchmark. Historically, HLS Therapeutics' own Cyclically Adjusted PB Ratio has ranged from 0.51 to 6.48 over the past decade. While the company's 10-year median is 1.39 vs. the industry median of 1.82, HLS Therapeutics has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Drug Manufacturers company?
The median Cyclically Adjusted PB Ratio among Drug Manufacturers companies is 1.82, based on 759 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. HLS Therapeutics's current Cyclically Adjusted PB Ratio of 0.68 is 62.6% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on HLS Therapeutics and its competitors. For the Drug Manufacturers industry, the median Cyclically Adjusted PB Ratio is 1.82 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. HLS Therapeutics's current Cyclically Adjusted PB Ratio is 0.68, which is 51% below median its own 10-year median of 1.39. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is HLS Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, HLS Therapeutics (TSX:HLS) is currently considered Fairly Valued. The stock's GF Value™ is C$4.51, compared to a current price of C$4.23 — trading 6.2% below its estimated fair value. The current Cyclically Adjusted PB Ratio is 0.68, which is 51% below median its 10-year median of 1.39 and 62.6% below the Drug Manufacturers industry median of 1.82. HLS Therapeutics' overall GF Score™ is 66/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For HLS Therapeutics (TSX:HLS), the current Cyclically Adjusted PB Ratio is 0.68 as of Jul. 14, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is HLS Therapeutics (TSX:HLS) Overvalued in 2026?

Based on GuruFocus' analysis, HLS Therapeutics stock appears to be undervalued. The current stock price of C$4.23 is trading 6.2% below its estimated GF Value™ of C$4.51. GuruFocus considers HLS Therapeutics to be Fairly Valued.

Key valuation signals for TSX:HLS:

  • Cyclically Adjusted PB Ratio: 0.68 (51% below median its 10-year median of 1.39)
  • GF Value™: C$4.51 vs. price of C$4.23 (6.2% below fair value)
  • GF Score™: 66/100 with 4 warning signs
  • Industry Position: 62.6% below the Drug Manufacturers median (#132 of 759)

No single metric tells the full story. See the TSX:HLS stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


HLS Therapeutics Business Description

Other Exchanges HLTRF:USA74D:Germany
Address 10 Carlson Court, Suite 701, Etobicoke, Toronto, ON, CAN, M9W 6L2
HLS Therapeutics Inc is a specialty pharmaceutical company. It is focused on the acquisition and commercialization of branded pharmaceutical products in the North American markets. The company's products include Clozaril, Vascepa, CSAN Pronto, and others. The company earns revenue in the form of product sales and royalties, out of which product sales contribute to the majority of the revenue. The company operates in Canada, the United States, and the Rest of world, with the majority of its revenue generated from Canada.
66GF Score

Get the complete analysis for TSX:HLS

Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

C$4.23
Price
C$4.51
GF Value