Addex Therapeutics (XSWX:ADXN) Cyclically Adjusted PB Ratio: 0.12 (As of Aug. 02, 2026) — 50% Above Median

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

What is Addex Therapeutics Cyclically Adjusted PB Ratio?

Addex Therapeutics XSWX:ADXN +3.45% Cyclically Adjusted PB Ratio is 0.12 as of Aug. 02, 2026, which is 50% above its 10-year median of 0.08. The stock has 6 warning signs investors should review. Among 697 Biotechnology companies, Addex Therapeutics ranks better than 87.37% on this metric.

As of today (2026-08-02), Addex Therapeutics's current share price is CHF0.042. Addex Therapeutics's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 was CHF0.36. Addex Therapeutics's Cyclically Adjusted PB Ratio for today is 0.12.

The historical rank and industry rank for Addex Therapeutics's Cyclically Adjusted PB Ratio or its related term are showing as below:

XSWX:ADXN' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 0.01   Med: 0.08   Max: 0.14
Current: 0.12

During the past years, Addex Therapeutics's highest Cyclically Adjusted PB Ratio was 0.14. The lowest was 0.01. And the median was 0.08.

XSWX:ADXN's Cyclically Adjusted PB Ratio is ranked better than
87.37% of 697 companies
in the Biotechnology industry
Industry Median: 1.6 vs XSWX:ADXN: 0.12

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Addex Therapeutics's adjusted book value per share data for the three months ended in Mar. 2026 was CHF0.028. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is CHF0.36 for the trailing ten years ended in Mar. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


Addex Therapeutics  (XSWX:ADXN) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


Addex Therapeutics Cyclically Adjusted PB Ratio Related Terms


Addex Therapeutics Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for Addex Therapeutics's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Addex Therapeutics Cyclically Adjusted PB Ratio Chart

Addex Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.02 0.07 0.15

Addex Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.09 0.12 0.16 0.15 0.11

XSWX:ADXN vs VRTX, REGN, RVMD: Cyclically Adjusted PB Ratio Comparison

For the Biotechnology subindustry, Addex Therapeutics's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Addex Therapeutics Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Addex Therapeutics's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Addex Therapeutics's Cyclically Adjusted PB Ratio falls into.



Addex Therapeutics Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

Addex Therapeutics's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=0.042/0.36
=0.12

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Addex Therapeutics's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 is calculated as:

For example, Addex Therapeutics's adjusted Book Value per Share data for the three months ended in Mar. 2026 was:

Adj_Book=Book Value per Share/CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=0.028/108.0600*108.0600
=0.028

Current CPI (Mar. 2026) = 108.0600.

Addex Therapeutics Quarterly Data

Book Value per Share CPI Adj_Book
201312 0.307 101.036 0.328
201406 0.208 101.517 0.221
201412 0.235 100.704 0.252
201506 0.249 100.464 0.268
201512 0.151 99.386 0.164
201606 0.104 100.088 0.112
201612 0.019 99.380 0.021
201706 0.180 100.285 0.194
201712 0.100 100.213 0.108
201806 1.603 101.435 1.708
201812 1.486 100.906 1.591
201903 0.000 101.571 0.000
201906 1.219 102.044 1.291
201909 0.000 101.396 0.000
201912 0.959 101.063 1.025
202003 0.817 101.048 0.874
202006 0.705 100.743 0.756
202009 0.594 100.585 0.638
202012 0.539 100.241 0.581
202103 0.608 100.800 0.652
202106 0.481 101.352 0.513
202109 0.391 101.533 0.416
202112 0.447 101.776 0.475
202203 0.342 103.205 0.358
202206 0.181 104.783 0.187
202209 0.150 104.835 0.155
202212 0.064 104.666 0.066
202303 0.050 106.245 0.051
202306 0.066 106.576 0.067
202309 0.040 106.570 0.041
202312 0.012 106.461 0.012
202403 -0.014 107.355 -0.014
202406 0.129 107.991 0.129
202409 0.113 107.468 0.114
202412 0.098 107.128 0.099
202503 0.084 107.722 0.084
202506 0.065 108.075 0.065
202509 0.051 107.710 0.051
202512 0.040 107.200 0.040
202603 0.028 108.060 0.028

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 0.12 mean?
Addex Therapeutics (XSWX:ADXN) has a Cyclically Adjusted PB Ratio of 0.12 as of Aug. 02, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Addex Therapeutics and its competitors. This is 50% above median its historical median of 0.08. Over the past decade, Addex Therapeutics' Cyclically Adjusted PB Ratio has ranged from 0.01 to 0.14. According to the industry distribution chart, Addex Therapeutics ranks #88 out of 697 companies in the Biotechnology industry, placing it in the top 12.6%.
Is Addex Therapeutics' Cyclically Adjusted PB Ratio too high?
Addex Therapeutics' current Cyclically Adjusted PB Ratio of 0.12 is 50% above median its 10-year median of 0.08. Over the past 10 years, this metric has ranged from a low of 0.01 to a high of 0.14. The Biotechnology industry median Cyclically Adjusted PB Ratio is 1.60. Addex Therapeutics' value of 0.12 is 92.5% below this industry median. Based on the distribution chart, Addex Therapeutics ranks #88 out of 697 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers.
How does Addex Therapeutics' Cyclically Adjusted PB Ratio compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Addex Therapeutics ranks #88 out of 697 companies for Cyclically Adjusted PB Ratio. This places Addex Therapeutics in the top 13% of its industry — outperforming the majority of peers. The industry median Cyclically Adjusted PB Ratio is 1.60. Addex Therapeutics' value of 0.12 is 92.5% below this benchmark. Historically, Addex Therapeutics' own Cyclically Adjusted PB Ratio has ranged from 0.01 to 0.14 over the past decade. While the company's 10-year median is 0.08 vs. the industry median of 1.60, Addex Therapeutics has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Biotechnology company?
The median Cyclically Adjusted PB Ratio among Biotechnology companies is 1.60, based on 697 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Addex Therapeutics's current Cyclically Adjusted PB Ratio of 0.12 is 92.5% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Addex Therapeutics and its competitors. For the Biotechnology industry, the median Cyclically Adjusted PB Ratio is 1.60 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Addex Therapeutics's current Cyclically Adjusted PB Ratio is 0.12, which is 50% above median its own 10-year median of 0.08. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Addex Therapeutics stock overvalued right now?
Addex Therapeutics (XSWX:ADXN) has a current Cyclically Adjusted PB Ratio of 0.12. The current Cyclically Adjusted PB Ratio is 0.12, which is 50% above median its 10-year median of 0.08 and 92.5% below the Biotechnology industry median of 1.60. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Addex Therapeutics (XSWX:ADXN), the current Cyclically Adjusted PB Ratio is 0.12 as of Aug. 02, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Addex Therapeutics Business Description

Address Chemin des Mines 9, Geneva, CHE, 1202
Addex Therapeutics Ltd is a clinical-stage biopharmaceutical company. The company is focused on the development and commercialization of an emerging class of novel orally available small-molecule drugs known as allosteric modulators. The company's geographical area of operations includes Switzerland and Europe. The Company operates in one segment, which is the discovery, development, and commercialization of small-molecule pharmaceutical products.