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Intellia TherapeuticsFRA:38I +0.77%66 Cyclically Adjusted PS Ratio is 12.72 as of Jul. 31, 2026, which is 16% below its 10-year median of 15.08. GuruFocus rates FRA:38I with a GF Score™ of 66/100 and a GF Value™ of €16.98 (Possible Value Trap). The stock has 5 warning signs investors should review. Among 538 Biotechnology companies, Intellia Therapeutics ranks worse than 71.75% on this metric.
The historical rank and industry rank for Intellia Therapeutics's Cyclically Adjusted PS Ratio or its related term are showing as below:
FRA:38I'
s Cyclically Adjusted PS Ratio Range Over the Past 10 Years
Min: 8.39 Med: 15.08 Max: 32
Current: 13.42
During the past years, Intellia Therapeutics's highest Cyclically Adjusted PS Ratio was 32.00. The lowest was 8.39. And the median was 15.08.
FRA:38I's Cyclically Adjusted PS Ratio is ranked worse than 71.75% of 538
companies
in the Biotechnology industry
Industry Median: 5.53
vs FRA:38I: 13.42
The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PS Ratio. The Cyclically Adjusted Revenue per Share is the average of the inflation adjusted revenue per share of a company over the past 10 years.
Intellia Therapeutics's adjusted revenue per share data for the three months ended in Mar. 2026 was €0.110. Add all the adjusted revenue per share for the past 10 years together and divide 10 will get our Cyclically Adjusted Revenue per Share, which is €0.72 for the trailing ten years ended in Mar. 2026.
Shiller PE for Stocks: The True Measure of Stock Valuation
Intellia Therapeutics (FRA:38I) Cyclically Adjusted PS Ratio Explanation
Compared with the regular PS Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PS Ratio smoothed out the fluctuations of revenue during business cycles. Therefore it is more accurate in reflecting the valuation of the company.
If a company has consistent business performance, the Cyclically Adjusted PS Ratio should give similar results to regular PS Ratio.
Intellia Therapeutics Cyclically Adjusted PS Ratio Related Terms
Intellia Therapeutics Cyclically Adjusted PS Ratio Historical Data
* Premium members only.
The historical data trend for Intellia Therapeutics's Cyclically Adjusted PS Ratio can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Intellia Therapeutics Cyclically Adjusted PS Ratio Chart
FRA:38I vs SEPN, AVBP, VIR: Cyclically Adjusted PS Ratio Comparison
For the Biotechnology subindustry, Intellia Therapeutics's Cyclically Adjusted PS Ratio, along with its competitors' market caps and Cyclically Adjusted PS Ratio data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Intellia Therapeutics Cyclically Adjusted PS Ratio vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Intellia Therapeutics's Cyclically Adjusted PS Ratio distribution charts can be found below:
* The bar in red indicates where Intellia Therapeutics's Cyclically Adjusted PS Ratio falls into.
Intellia Therapeutics Cyclically Adjusted PS Ratio Calculation
Like the Shiller PE Ratio, the Cyclically Adjusted PS Ratio takes the Revenue per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/S calculation. Because it considers this 10-year average, it's often referred to as the CAPS Ratio.
The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PS Ratio.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.
What does a Cyclically Adjusted PS Ratio of 12.72 mean?
Intellia Therapeutics (FRA:38I) has a Cyclically Adjusted PS Ratio of 12.72 as of Jul. 31, 2026. Cyclically Adjusted PS Ratio is the ratio of share price to a company's inflation-adjusted revenue per share over a 10-year period. View historical data on Intellia Therapeutics and its competitors. This is 16% below median its historical median of 15.08. Over the past decade, Intellia Therapeutics' Cyclically Adjusted PS Ratio has ranged from 8.39 to 32.00. According to the industry distribution chart, Intellia Therapeutics ranks #386 out of 538 companies in the Biotechnology industry, placing it in the top 71.7%.
Is Intellia Therapeutics' Cyclically Adjusted PS Ratio too high?
Intellia Therapeutics' current Cyclically Adjusted PS Ratio of 12.72 is 16% below median its 10-year median of 15.08. Over the past 10 years, this metric has ranged from a low of 8.39 to a high of 32.00. The Biotechnology industry median Cyclically Adjusted PS Ratio is 5.53. Intellia Therapeutics' value of 12.72 is 130% above this industry median. Based on the distribution chart, Intellia Therapeutics ranks #386 out of 538 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Intellia Therapeutics has a GF Score™ of 66/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does Intellia Therapeutics' Cyclically Adjusted PS Ratio compare to SEPN and AVBP?
According to the Biotechnology industry distribution chart, Intellia Therapeutics ranks #386 out of 538 companies for Cyclically Adjusted PS Ratio. This places Intellia Therapeutics in the lower half of its industry. The industry median Cyclically Adjusted PS Ratio is 5.53. Intellia Therapeutics' value of 12.72 is 130% above this benchmark. Historically, Intellia Therapeutics' own Cyclically Adjusted PS Ratio has ranged from 8.39 to 32.00 over the past decade. While the company's 10-year median is 15.08 vs. the industry median of 5.53, Intellia Therapeutics has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PS Ratio for a Biotechnology company?
The median Cyclically Adjusted PS Ratio among Biotechnology companies is 5.53, based on 538 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PS Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PS Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Intellia Therapeutics's current Cyclically Adjusted PS Ratio of 12.72 is 130% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PS Ratio mean?
A high Cyclically Adjusted PS Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PS Ratio is the ratio of share price to a company's inflation-adjusted revenue per share over a 10-year period. View historical data on Intellia Therapeutics and its competitors. For the Biotechnology industry, the median Cyclically Adjusted PS Ratio is 5.53 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Intellia Therapeutics's current Cyclically Adjusted PS Ratio is 12.72, which is 16% below median its own 10-year median of 15.08. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Intellia Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Intellia Therapeutics (FRA:38I) is currently considered Possible Value Trap. The stock's GF Value™ is €16.98, compared to a current price of €9.16 — trading 46.1% below its estimated fair value. The current Cyclically Adjusted PS Ratio is 12.72, which is 16% below median its 10-year median of 15.08 and 130% above the Biotechnology industry median of 5.53. Intellia Therapeutics' overall GF Score™ is 66/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PS Ratio calculated?
Cyclically Adjusted PS Ratio is calculated from a company's financial statements. For Intellia Therapeutics (FRA:38I), the current Cyclically Adjusted PS Ratio is 12.72 as of Jul. 31, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Intellia Therapeutics (FRA:38I) Overvalued in 2026?
Based on GuruFocus' analysis, Intellia Therapeutics stock appears to be undervalued.
The current stock price of €9.16 is trading 46.1% below its estimated GF Value™ of €16.98.
GuruFocus considers Intellia Therapeutics to be Possible Value Trap.
Key valuation signals for FRA:38I:
Cyclically Adjusted PS Ratio: 12.72 (16% below median its 10-year median of 15.08)
GF Value™: €16.98 vs. price of €9.16 (46.1% below fair value)
Industry Position: 130% above the Biotechnology median (#386 of 538)
No single metric tells the full story. See the FRA:38I stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Intellia Therapeutics is a gene-editing company focused on the development of Crispr/Cas9-based therapeutics. Crispr/Cas9 stands for Clustered Regularly Interspaced Short Palindromic Repeats (Crispr)/Crispr-associated protein 9 (Cas9), which is a revolutionary technology for precisely altering specific sequences of genomic DNA. Intellia is focused on using this technology to treat genetically defined diseases. It's evaluating multiple gene editing approaches using in vivo and ex vivo therapies to address diseases with high unmet medical needs, including ATTR amyloidosis, hereditary angioedema, sickle cell disease, and immuno-oncology. Intellia has formed collaborations with several companies to advance its pipeline, including narrow-moat Regeneron and wide-moat Novartis.
66GF Score
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