Natera (HAM:45E) Cyclically Adjusted PS Ratio: (As of Aug. 21, 2026)

Author: Vera Yuan Vera Yuan
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Director of Data and Quant Analytics at GuruFocus
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Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

HAM:45E Natera Inc HAM:45E
59 GF Score
Price €274.40
GF Value €179.22
Valuation Significantly Overvalued
! 6 Warning Signs
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What is Natera Cyclically Adjusted PS Ratio?

Note: If the price history is too short, we do not calculate current Cyclically Adjusted PS Ratio for this stock. All the historical data is shown as the company's primary share's data instead.

Shiller PE for Stocks: The True Measure of Stock Valuation


Natera  (HAM:45E) Cyclically Adjusted PS Ratio Explanation

Compared with the regular PS Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PS Ratio smoothed out the fluctuations of revenue during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PS Ratio should give similar results to regular PS Ratio.


Natera Cyclically Adjusted PS Ratio Related Terms


Natera Cyclically Adjusted PS Ratio Historical Data

* Premium members only.

The historical data trend for Natera's Cyclically Adjusted PS Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Natera Cyclically Adjusted PS Ratio Chart

Natera Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PS Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 9.89 21.67 26.55

Natera Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Cyclically Adjusted PS Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 21.23 19.37 26.55 21.94 28.27

HAM:45E vs : Cyclically Adjusted PS Ratio Comparison

For the Diagnostics & Research subindustry, Natera's Cyclically Adjusted PS Ratio, along with its competitors' market caps and Cyclically Adjusted PS Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Natera Cyclically Adjusted PS Ratio vs Medical Diagnostics & Research Industry

For the Medical Diagnostics & Research industry and Healthcare sector, Natera's Cyclically Adjusted PS Ratio distribution charts can be found below:

* The bar in red indicates where Natera's Cyclically Adjusted PS Ratio falls into.


HAM:45E
59GF Score
Natera Inc HAM:45E
Cyclically Adjusted PS Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Natera Cyclically Adjusted PS Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PS Ratio takes the Revenue per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/S calculation. Because it considers this 10-year average, it's often referred to as the CAPS Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PS Ratio.

Natera's Cyclically Adjusted Revenue per Share for the quarter that ended in Jun. 2026 is calculated as:

For example, Natera's adjusted Revenue per Share data for the three months ended in Jun. 2026 was:

Adj_RevenuePerShare=Revenue per Share/CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=4.56/333.9520*333.9520
=4.560

Current CPI (Jun. 2026) = 333.9520.

Natera Quarterly Data

Revenue per Share CPI Adj_RevenuePerShare
201609 0.923 241.428 1.277
201612 0.809 241.432 1.119
201703 0.870 243.801 1.192
201706 0.877 244.955 1.196
201709 0.878 246.819 1.188
201712 0.798 246.524 1.081
201803 0.934 249.554 1.250
201806 0.990 251.989 1.312
201809 0.924 252.439 1.222
201812 0.949 251.233 1.261
201903 0.941 254.202 1.236
201906 0.965 256.143 1.258
201909 1.004 256.759 1.306
201912 0.978 256.974 1.271
202003 1.087 258.115 1.406
202006 0.971 257.797 1.258
202009 1.030 260.280 1.322
202012 1.077 260.474 1.381
202103 1.476 264.877 1.861
202106 1.338 271.696 1.645
202109 1.452 274.310 1.768
202112 1.615 278.802 1.934
202203 1.844 287.504 2.142
202206 1.941 296.311 2.188
202209 2.192 296.808 2.466
202212 1.964 296.797 2.210
202303 2.020 301.836 2.235
202306 2.122 305.109 2.323
202309 2.183 307.789 2.369
202312 2.391 306.746 2.603
202403 2.800 312.332 2.994
202406 3.126 314.175 3.323
202409 3.201 315.301 3.390
202412 3.460 315.605 3.661
202503 3.445 319.799 3.597
202506 3.475 322.561 3.598
202509 3.678 324.800 3.782
202512 4.108 324.054 4.233
202603 4.259 330.213 4.307
202606 4.560 333.952 4.560

Add all the adjusted revenue per share together and divide 10 will get our Cyclically Adjusted Revenue per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

Is Natera (HAM:45E) Overvalued in 2026?

Based on GuruFocus' analysis, Natera stock appears to be overvalued. The current stock price of €274.40 is trading 53.1% above its estimated GF Value™ of €179.22. GuruFocus considers Natera to be Significantly Overvalued.

Key valuation signals for HAM:45E:

  • Cyclically Adjusted PS Ratio:
  • GF Value™: €179.22 vs. price of €274.40 (53.1% above fair value)
  • GF Score™: 59/100 with 6 warning signs

No single metric tells the full story. See the HAM:45E stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Natera Business Description

Comparable Companies
Other Exchanges NTRA:USANTRA:Mexico
Address 13011 McCallen Pass, Building A Suite 100, Austin, TX, USA, 78753
Natera Inc is a diagnostic and research company with proprietary molecular and bioinformatics technology. The company's key product offerings include its Panorama Non-Invasive Prenatal Test (NIPT) which screens for chromosomal abnormalities of a fetus as well as in twin pregnancies, typically with a blood draw from the mother, Horizon Carrier Screening (HCS) to determine carrier status for a large number of severe genetic diseases that could be passed on to the carrier's children, Signatera molecular residual disease (MRD) test, which detects circulating tumor DNA in patients previously diagnosed with cancer to assess molecular residual disease and monitor for recurrence; and Prospera, to assess organ transplant rejection.
59GF Score

Get the complete analysis for HAM:45E

Cyclically Adjusted PS Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€274.40
Price
€179.22
GF Value