Illumina (WBO:ILMN) Cyclically Adjusted PS Ratio: (As of Sep. 21, 2026)

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
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Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

WBO:ILMN Illumina Inc WBO:ILMN
58 GF Score
Price €210.40
GF Value €117.44
Valuation Significantly Overvalued
! 7 Warning Signs
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What is Illumina Cyclically Adjusted PS Ratio?

Shiller PE for Stocks: The True Measure of Stock Valuation


Illumina  (WBO:ILMN) Cyclically Adjusted PS Ratio Explanation

Compared with the regular PS Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PS Ratio smoothed out the fluctuations of revenue during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PS Ratio should give similar results to regular PS Ratio.


Illumina Cyclically Adjusted PS Ratio Related Terms


Illumina Cyclically Adjusted PS Ratio Historical Data

* Premium members only.

The historical data trend for Illumina's Cyclically Adjusted PS Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Illumina Cyclically Adjusted PS Ratio Chart

Illumina Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PS Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 19.18 9.09 5.60 5.36 4.48

Illumina Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Cyclically Adjusted PS Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 3.24 3.10 4.46 4.08 5.79

WBO:ILMN vs MTD, LH, DGX: Cyclically Adjusted PS Ratio Comparison

For the Diagnostics & Research subindustry, Illumina's Cyclically Adjusted PS Ratio, along with its competitors' market caps and Cyclically Adjusted PS Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Illumina Cyclically Adjusted PS Ratio vs Medical Diagnostics & Research Industry

For the Medical Diagnostics & Research industry and Healthcare sector, Illumina's Cyclically Adjusted PS Ratio distribution charts can be found below:

* The bar in red indicates where Illumina's Cyclically Adjusted PS Ratio falls into.


WBO:ILMN
58GF Score
Illumina Inc WBO:ILMN
Cyclically Adjusted PS Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
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Illumina Cyclically Adjusted PS Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PS Ratio takes the Revenue per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/S calculation. Because it considers this 10-year average, it's often referred to as the CAPS Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PS Ratio.

Illumina's Cyclically Adjusted Revenue per Share for the quarter that ended in Jun. 2026 is calculated as:

For example, Illumina's adjusted Revenue per Share data for the three months ended in Jun. 2026 was:

Adj_RevenuePerShare=Revenue per Share/CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=6.526/333.9520*333.9520
=6.526

Current CPI (Jun. 2026) = 333.9520.

Illumina Quarterly Data

Revenue per Share CPI Adj_RevenuePerShare
201609 3.678 241.428 5.088
201612 3.880 241.432 5.367
201703 3.817 243.801 5.228
201706 4.092 244.955 5.579
201709 4.110 246.819 5.561
201712 4.465 246.524 6.048
201803 4.299 249.554 5.753
201806 4.707 251.989 6.238
201809 4.922 252.439 6.511
201812 5.099 251.233 6.778
201903 5.000 254.202 6.569
201906 5.005 256.143 6.525
201909 5.512 256.759 7.169
201912 5.816 256.974 7.558
202003 5.268 258.115 6.816
202006 3.884 257.797 5.031
202009 4.593 260.280 5.893
202012 5.438 260.474 6.972
202103 6.173 264.877 7.783
202106 6.359 271.696 7.816
202109 6.143 274.310 7.479
202112 6.676 278.802 7.997
202203 6.856 287.504 7.964
202206 6.945 296.311 7.827
202209 7.051 296.808 7.933
202212 6.724 296.797 7.566
202303 6.412 301.836 7.094
202306 6.839 305.109 7.486
202309 6.510 307.789 7.063
202312 6.563 306.746 7.145
202403 6.235 312.332 6.667
202406 6.496 314.175 6.905
202409 6.144 315.301 6.507
202412 6.469 315.605 6.845
202503 6.221 319.799 6.496
202506 5.940 322.561 6.150
202509 6.018 324.800 6.188
202512 6.472 324.054 6.670
202603 6.055 330.213 6.124
202606 6.526 333.952 6.526

Add all the adjusted revenue per share together and divide 10 will get our Cyclically Adjusted Revenue per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

Is Illumina (WBO:ILMN) Overvalued in 2026?

Based on GuruFocus' analysis, Illumina stock appears to be overvalued. The current stock price of €210.40 is trading 79.2% above its estimated GF Value™ of €117.44. GuruFocus considers Illumina to be Significantly Overvalued.

Key valuation signals for WBO:ILMN:

  • Cyclically Adjusted PS Ratio:
  • GF Value™: €117.44 vs. price of €210.40 (79.2% above fair value)
  • GF Score™: 58/100 with 7 warning signs

No single metric tells the full story. See the WBO:ILMN stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Illumina Business Description

Address 5200 Illumina Way, San Diego, CA, USA, 92122
Illumina provides tools and services to analyze genetic material with life science and clinical lab applications. The company generates over 90% of its revenue from sequencing instruments, consumables, and services. Illumina's high-throughput technology enables whole genome sequencing in humans and other large organisms. Its lower throughput tools enable applications that require smaller data outputs, such as viral and cancer tumor screening. Illumina also sells microarrays (9% of 2024 sales) that enable lower-cost, focused genetic screening with primarily consumer and agricultural applications.
58GF Score

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Cyclically Adjusted PS Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€210.40
Price
€117.44
GF Value