OPKO Health (FRA:XCY) Cyclically Adjusted Revenue per Share: €1.68 (As of Jun. 2026)

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

FRA:XCY OPKO Health Inc FRA:XCY
57 GF Score
Price €1.40
GF Value €0.87
Valuation Significantly Overvalued
! 5 Warning Signs
View Full Analysis

What is OPKO Health Cyclically Adjusted Revenue per Share?

OPKO Health FRA:XCY -6.04% 57 Cyclically Adjusted Revenue per Share is €1.68 as of Jun. 2026. GuruFocus rates FRA:XCY with a GF Score™ of 57/100 and a GF Value™ of €0.87 (Significantly Overvalued). The stock has 5 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Revenue per Share and the Cyclically Adjusted PS Ratio. The Cyclically Adjusted Revenue per Share is the average of the inflation adjusted Revenue per Share of a company over the past 10 years.

OPKO Health's adjusted revenue per share for the three months ended in Jun. 2026 was €0.188. Add all the adjusted revenue per share for the past 10 years together and divide the count will get our Cyclically Adjusted Revenue per Share, which is €1.68 for the trailing ten years ended in Jun. 2026.

During the past 12 months, OPKO Health's average Cyclically Adjusted Revenue Growth Rate was -5.90% per year. During the past 3 years, the average Cyclically Adjusted Revenue Growth Rate was 4.80% per year. During the past 5 years, the average Cyclically Adjusted Revenue Growth Rate was 10.90% per year. During the past 10 years, the average Cyclically Adjusted Revenue Growth Rate was 22.00% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the Cyclically Adjusted Revenue Growth Rate using Cyclically Adjusted Revenue per Share data.

During the past 13 years, the highest 3-Year average Cyclically Adjusted Revenue Growth Rate of OPKO Health was 57.00% per year. The lowest was -3.90% per year. And the median was 23.30% per year.

As of today (2026-07-30), OPKO Health's current stock price is €1.40. OPKO Health's Cyclically Adjusted Revenue per Share for the quarter that ended in Jun. 2026 was €1.68. OPKO Health's Cyclically Adjusted PS Ratio of today is 0.83.

During the past 13 years, the highest Cyclically Adjusted PS Ratio of OPKO Health was 29.97. The lowest was 0.48. And the median was 2.16.


OPKO Health  (FRA:XCY) Cyclically Adjusted Revenue per Share Explanation

If a company grows much fast than inflation, Cyclically Adjusted Revenue per Share may underestimate the company's revenue. Cyclically Adjusted PS Ratio can seem to be too high even the actual PS Ratio is low.

For the Cyclically Adjusted PS Ratio, the revenue per share of the past 10 years are inflation-adjusted and averaged. The result is used for P/S calculation. Since it looks at the average over the last 10 years, the Cyclically Adjusted PS Ratio is also called CAPS Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PS Ratio. The Cyclically Adjusted Revenue per Share is the average of the inflation adjusted revenue per share of a company over the past 10 years.

OPKO Health's Cyclically Adjusted PS Ratio of today is calculated as

Cyclically Adjusted PS Ratio=Share Price/Cyclically Adjusted Revenue per Share
=1.40/1.68
=0.83

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

During the past 13 years, the highest Cyclically Adjusted PS Ratio of OPKO Health was 29.97. The lowest was 0.48. And the median was 2.16.


Be Aware

Cyclically Adjusted PS Ratio works better for cyclical companies. It gives you a better idea on the company's real revenue value.


OPKO Health Cyclically Adjusted Revenue per Share Related Terms


OPKO Health Cyclically Adjusted Revenue per Share Historical Data

* Premium members only.

The historical data trend for OPKO Health's Cyclically Adjusted Revenue per Share can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

OPKO Health Cyclically Adjusted Revenue per Share Chart

OPKO Health Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted Revenue per Share
Get a 7-Day Free Trial Premium Member Only Premium Member Only 1.35 1.54 1.72 1.87 1.71

OPKO Health Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Cyclically Adjusted Revenue per Share Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 1.71 1.66 1.71 1.61 1.68

FRA:XCY vs CSTL, FRNM, PSNL: Cyclically Adjusted Revenue per Share Comparison

For the Diagnostics & Research subindustry, OPKO Health's Cyclically Adjusted PS Ratio, along with its competitors' market caps and Cyclically Adjusted PS Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


OPKO Health Cyclically Adjusted PS Ratio vs Medical Diagnostics & Research Industry

For the Medical Diagnostics & Research industry and Healthcare sector, OPKO Health's Cyclically Adjusted PS Ratio distribution charts can be found below:

* The bar in red indicates where OPKO Health's Cyclically Adjusted PS Ratio falls into.


FRA:XCY
57GF Score
OPKO Health Inc FRA:XCY
Cyclically Adjusted Revenue per Share is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

OPKO Health Cyclically Adjusted Revenue per Share Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Revenue per Share and the Cyclically Adjusted PS Ratio. The Cyclically Adjusted Revenue per Share is the average of the inflation adjusted Revenue per Share of a company over the past 10 years.

What is Cyclically Adjusted Revenue per Share? How do we calculate Cyclically Adjusted Revenue per Share?

Cyclically Adjusted Revenue per Share is the average of the inflation adjusted Revenue per Share of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the Cyclically Adjusted Revenue per Share of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the revenue per share from 2001 through 2010.

We adjusted the 2001 revenue per share data with the total inflation from 2001 through 2010 to the equivalent revenue in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart's revenue is $1 a share in 2001, then the 2001's equivalent revenue in 2010 is $1.4 a share. If Wal-Mart's revenue is $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 revenue in 2010 is $1.35. So on and so forth, you get the equivalent revenue per share of past 10 years. Then you add them together and divided the sum by the count to get Cyclically Adjusted Revenue per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, OPKO Health's adjusted Revenue per Share data for the three months ended in Jun. 2026 was:

Adj_RevenuePerShare= Revenue per Share /CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=0.188/333.9520*333.9520
=0.188

Current CPI (Jun. 2026) = 333.9520.

OPKO Health Quarterly Data

Revenue per Share CPI Adj_RevenuePerShare
201609 0.481 241.428 0.665
201612 0.282 241.432 0.390
201703 0.446 243.801 0.611
201706 0.462 244.955 0.630
201709 0.369 246.819 0.499
201712 0.243 246.524 0.329
201803 0.370 249.554 0.495
201806 0.403 251.989 0.534
201809 0.382 252.439 0.505
201812 0.340 251.233 0.452
201903 0.336 254.202 0.441
201906 0.342 256.143 0.446
201909 0.354 256.759 0.460
201912 0.324 256.974 0.421
202003 0.299 258.115 0.387
202006 0.418 257.797 0.541
202009 0.567 260.280 0.727
202012 0.635 260.474 0.814
202103 0.715 264.877 0.901
202106 0.568 271.696 0.698
202109 0.503 274.310 0.612
202112 0.545 278.802 0.653
202203 0.453 287.504 0.526
202206 0.411 296.311 0.463
202209 0.242 296.808 0.272
202212 0.233 296.797 0.262
202303 0.295 301.836 0.326
202306 0.326 305.109 0.357
202309 0.223 307.789 0.242
202312 0.222 306.746 0.242
202403 0.226 312.332 0.242
202406 0.243 314.175 0.258
202409 0.157 315.301 0.166
202412 0.259 315.605 0.274
202503 0.207 319.799 0.216
202506 0.173 322.561 0.179
202509 0.166 324.800 0.171
202512 0.165 324.054 0.170
202603 0.142 330.213 0.144
202606 0.188 333.952 0.188

Add all the adjusted revenue per share together and divide 10 will get our Cyclically Adjusted Revenue per Share.

What does a Cyclically Adjusted Revenue per Share of €1.68 mean?
OPKO Health (FRA:XCY) has a Cyclically Adjusted Revenue per Share of €1.68 as of Jun. 2026. Cyclically adjusted revenue per share represents the company's inflation-adjusted revenue per share over a 10-year period. View historical data on OPKO Health and its competitors.
Is OPKO Health's Cyclically Adjusted Revenue per Share too high?
OPKO Health's current Cyclically Adjusted Revenue per Share is €1.68. Overall, OPKO Health has a GF Score™ of 57/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does OPKO Health's Cyclically Adjusted Revenue per Share compare to CSTL and FRNM?
OPKO Health's Cyclically Adjusted Revenue per Share of €1.68 can be compared against companies in the Medical Diagnostics & Research industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted Revenue per Share for a Medical Diagnostics & Research company?
A good Cyclically Adjusted Revenue per Share depends on the Medical Diagnostics & Research industry context. However, Cyclically Adjusted Revenue per Share should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted Revenue per Share mean?
A high Cyclically Adjusted Revenue per Share can signal that a stock is expensive relative to its fundamentals. Cyclically adjusted revenue per share represents the company's inflation-adjusted revenue per share over a 10-year period. View historical data on OPKO Health and its competitors. OPKO Health's current Cyclically Adjusted Revenue per Share is €1.68. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is OPKO Health stock overvalued right now?
Based on GuruFocus' analysis, OPKO Health (FRA:XCY) is currently considered Significantly Overvalued. The stock's GF Value™ is €0.87, compared to a current price of €1.40 — trading 60.9% above its estimated fair value. The current Cyclically Adjusted Revenue per Share is €1.68. OPKO Health's overall GF Score™ is 57/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted Revenue per Share calculated?
Cyclically Adjusted Revenue per Share is calculated from a company's financial statements. For OPKO Health (FRA:XCY), the current Cyclically Adjusted Revenue per Share is €1.68 as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is OPKO Health (FRA:XCY) Overvalued in 2026?

Based on GuruFocus' analysis, OPKO Health stock appears to be overvalued. The current stock price of €1.40 is trading 60.9% above its estimated GF Value™ of €0.87. GuruFocus considers OPKO Health to be Significantly Overvalued.

Key valuation signals for FRA:XCY:

  • Cyclically Adjusted Revenue per Share: €1.68
  • GF Value™: €0.87 vs. price of €1.40 (60.9% above fair value)
  • GF Score™: 57/100 with 5 warning signs

No single metric tells the full story. See the FRA:XCY stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


OPKO Health Business Description

Address 4400 Biscayne Boulevard, Miami, FL, USA, 33137
OPKO Health Inc is a diversified biotechnology company that operates pharmaceutical and diagnostic development programs. Its segments include pharmaceutical and diagnostics. The Pharmaceutical segment consists of its pharmaceutical operations in Chile, Mexico, Ireland, Israel, Spain, Ecuador, France, the United States, and its pharmaceutical research and development operations. The Diagnostics segment consists of clinical and genomics laboratory operations through BioReference and point-of-care operations. It generates the majority of its revenue from the Diagnostics segment.
57GF Score

Get the complete analysis for FRA:XCY

Cyclically Adjusted Revenue per Share is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€1.40
Price
€0.87
GF Value