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A high Debt-to-EBITDA ratio generally means that a company may spend more time to paying off its debt. According to Joel Tillinghast's BIG MONEY THINKS SMALL: Biases, Blind Spots, and Smarter Investing, a ratio of Debt-to-EBITDA exceeding four is usually considered scary unless tangible assets cover the debt.
The historical rank and industry rank for argenx SE's Debt-to-EBITDA or its related term are showing as below:
ARGX'
s Debt-to-EBITDA Range Over the Past 10 Years
Min: -0.1 Med: -0.02 Max: 0.37
Current: 0.03
During the past 13 years, the highest Debt-to-EBITDA Ratio of argenx SE was 0.37. The lowest was -0.10. And the median was -0.02.
ARGX's Debt-to-EBITDA is ranked better than 93.94% of 297
companies
in the Biotechnology industry
Industry Median: 1.21
vs ARGX: 0.03
A high Debt-to-EBITDA ratio generally means that a company may spend more time to paying off its debt.
According to Joel Tillinghast's BIG MONEY THINKS SMALL: Biases, Blind Spots, and Smarter Investing, a ratio of Debt-to-EBITDA exceeding four is usually considered scary unless tangible assets cover the debt.
argenx SE Debt-to-EBITDA Related Terms
argenx SE Debt-to-EBITDA Historical Data
* Premium members only.
The historical data trend for argenx SE's Debt-to-EBITDA can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
ARGX vs VRTX, REGN, RVMD: Debt-to-EBITDA Comparison
For the Biotechnology subindustry, argenx SE's Debt-to-EBITDA, along with its competitors' market caps and Debt-to-EBITDA data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
argenx SE Debt-to-EBITDA vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, argenx SE's Debt-to-EBITDA distribution charts can be found below:
* The bar in red indicates where argenx SE's Debt-to-EBITDA falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
In the calculation of annual Debt-to-EBITDA, the EBITDA of the last fiscal year is used. In calculating the annualized quarterly data,
the EBITDA data used here is four times the quarterly (Jun. 2026) EBITDA data.
argenx SE (ARGX) has a Debt-to-EBITDA of 0.02 as of Jun. 2026. Debt-to-EBITDA ratio represents the ratio of total debt to total earnings before interest, taxes, depreciation and amortization. View historical data on argenx SE. According to the industry distribution chart, argenx SE ranks #18 out of 297 companies in the Biotechnology industry, placing it in the top 6.1%.
Is argenx SE's Debt-to-EBITDA too high?
argenx SE's current Debt-to-EBITDA is 0.02. The Biotechnology industry median Debt-to-EBITDA is 1.21. argenx SE's value of 0.02 is 98.3% below this industry median. Based on the distribution chart, argenx SE ranks #18 out of 297 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, argenx SE has a GF Score™ of 78/100 and is considered Significantly Undervalued, reflecting its overall financial health beyond just this single metric.
How does argenx SE's Debt-to-EBITDA compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, argenx SE ranks #18 out of 297 companies for Debt-to-EBITDA. This places argenx SE in the top 6% of its industry — outperforming the majority of peers. The industry median Debt-to-EBITDA is 1.21. argenx SE's value of 0.02 is 98.3% below this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Debt-to-EBITDA for a Biotechnology company?
The median Debt-to-EBITDA among Biotechnology companies is 1.21, based on 297 companies in the industry. Companies in the top quartile (top 25%) have a Debt-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, Debt-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. argenx SE's current Debt-to-EBITDA of 0.02 is 98.3% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Debt-to-EBITDA mean?
A high Debt-to-EBITDA can signal that a stock is expensive relative to its fundamentals. Debt-to-EBITDA ratio represents the ratio of total debt to total earnings before interest, taxes, depreciation and amortization. View historical data on argenx SE. For the Biotechnology industry, the median Debt-to-EBITDA is 1.21 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. argenx SE's current Debt-to-EBITDA is 0.02. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is argenx SE stock overvalued right now?
Based on GuruFocus' analysis, argenx SE (ARGX) is currently considered Significantly Undervalued. The stock's GF Value™ is $1,419.51, compared to a current price of $865.04 — trading 39.1% below its estimated fair value. The current Debt-to-EBITDA is 0.02 and 98.3% below the Biotechnology industry median of 1.21. argenx SE's overall GF Score™ is 78/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Debt-to-EBITDA calculated?
Debt-to-EBITDA is calculated from a company's financial statements. For argenx SE (ARGX), the current Debt-to-EBITDA is 0.02 as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is argenx SE (ARGX) Overvalued in 2026?
Based on GuruFocus' analysis, argenx SE stock appears to be undervalued.
The current stock price of $865.04 is trading 39.1% below its estimated GF Value™ of $1,419.51.
GuruFocus considers argenx SE to be Significantly Undervalued.
Key valuation signals for ARGX:
Debt-to-EBITDA: 0.02
GF Value™: $1,419.51 vs. price of $865.04 (39.1% below fair value)
Industry Position: 98.3% below the Biotechnology median (#18 of 297)
No single metric tells the full story. See the ARGX stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Argenx is a Dutch biopharmaceutical company focused on developing antibody-based therapies for rare autoimmune diseases. The company's lead product, Vyvgart (efgartigimod), was approved by the FDA in December 2021 for the treatment of generalized myasthenia gravis (gMG). In 2022, Argenx also received FDA approval for Vyvgart Hytrulo, a subcutaneous formulation of Vyvgart, offering a more convenient option compared with Vyvgart's intravenous administration. In 2024, the FDA approved Vyvgart Hytrulo for Chronic Inflammatory Demyelinating Polyneuropathy, a rare immune-mediated neuromuscular disorder of the peripheral nervous system. Argenx is focused on innovation and developing its pipeline for treatments such as primary immune thrombocytopenia, thyroid eye disease, and Sjogren's Disease.
78GF Score
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