ARGX (argenx SE) 3-Year ROIIC % : 67.34% (As of Dec. 2025)

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ARGX argenx SE ARGX
78 GF Score
Price $860.94
GF Value $1,449.85
Valuation Significantly Undervalued
! 5 Warning Signs
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What is argenx SE 3-Year ROIIC %?

argenx SE ARGX +0.30% 78 3-Year ROIIC % is 67.34 as of Dec. 2025. GuruFocus rates ARGX with a GF Score™ of 78/100 and a GF Value™ of $1,449.85 (Significantly Undervalued). The stock has 5 warning signs investors should review. Among 1,322 Biotechnology companies, argenx SE ranks better than 75.26% on this metric.

3-Year Return on Invested Incremental Capital (3-Year ROIIC %) measures the change in earnings as a percentage of change in investment over 3-year. argenx SE's 3-Year ROIIC % for the quarter that ended in Dec. 2025 was 67.34%. High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.

The industry rank for argenx SE's 3-Year ROIIC % or its related term are showing as below:

ARGX's 3-Year ROIIC % is ranked better than
75.26% of 1322 companies
in the Biotechnology industry
Industry Median: -4.835 vs ARGX: 67.34

argenx SE  (NAS:ARGX) 3-Year ROIIC % Explanation

Return on Incremental Invested Capital (ROIIC) is an extension of Return on Investment Capital (ROIC). ROIC % tells investors how efficiently that profitability is earned per dollar of company capital. ROIIC narrows the focus even further and shows how profitable each additional unit of capital investment could be. ROIIC % is a more powerful metric than ROIC because it measures how much money the company can generate going forward on future capital investments.

High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.

Be Aware

It's important to keep in mind that when tracking ROIIC, the metric is better suited to forecasting the trend of future returns rather than measuring current return on investment.


argenx SE 3-Year ROIIC % Related Terms


argenx SE 3-Year ROIIC % Historical Data

* Premium members only.

The historical data trend for argenx SE's 3-Year ROIIC % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

argenx SE 3-Year ROIIC % Chart

argenx SE Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
3-Year ROIIC %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -72.02 -89.49 2.94 15.13 67.34

argenx SE Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
3-Year ROIIC % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 0.00 67.34 0.00

ARGX vs VRTX, REGN, ALNY: 3-Year ROIIC % Comparison

For the Biotechnology subindustry, argenx SE's 3-Year ROIIC %, along with its competitors' market caps and 3-Year ROIIC % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


argenx SE 3-Year ROIIC % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, argenx SE's 3-Year ROIIC % distribution charts can be found below:

* The bar in red indicates where argenx SE's 3-Year ROIIC % falls into.


ARGX
78GF Score
argenx SE ARGX
3-Year ROIIC % is just one metric. See GF Score™, valuation, warning signs, and more.
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argenx SE 3-Year ROIIC % Calculation

argenx SE's 3-Year ROIIC % for the quarter that ended in Dec. 2025 is calculated as:

3-Year ROIIC %=3-Year Incremental Net Operating Profit After Taxes (NOPAT)**/3-Year Incremental Invested Capital**
=( 1054.615 (Dec. 2025) - -704.373187 (Dec. 2022) )/( 3547.682 (Dec. 2025) - 746.669 (Dec. 2022) )
=1758.988187/2801.013
=62.80%***

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

** Annual data of NOPAT and Invested Capital was used to calculate 3-Year ROIIC %.
*** Please be aware that the ROIIC (Return on Invested Capital) calculations are based on company-level data using the primary share class. The calculated data provided is for demonstration purposes and may slightly differ from the results displayed in the title due to potential variations caused by currency exchange rate differences throughout the year.

Frequently Asked Questions Learn more about 3-Year ROIIC % →
What does a 3-Year ROIIC % of 67.34 mean?
argenx SE (ARGX) has a 3-Year ROIIC % of 67.34 as of Dec. 2025. 3-Year ROIIC % measures the change in earnings as a percentage of change in investment over 3-year. View historical data on argenx SE and its competitors. According to the industry distribution chart, argenx SE ranks #327 out of 1322 companies in the Biotechnology industry, placing it in the top 24.7%.
Is argenx SE's 3-Year ROIIC % too high?
argenx SE's current 3-Year ROIIC % is 67.34. Based on the distribution chart, argenx SE ranks #327 out of 1322 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, argenx SE has a GF Score™ of 78/100 and is considered Significantly Undervalued, reflecting its overall financial health beyond just this single metric.
How does argenx SE's 3-Year ROIIC % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, argenx SE ranks #327 out of 1322 companies for 3-Year ROIIC %. This places argenx SE in the top 25% of its industry — outperforming the majority of peers. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good 3-Year ROIIC % for a Biotechnology company?
A good 3-Year ROIIC % depends on the Biotechnology industry context. However, 3-Year ROIIC % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high 3-Year ROIIC % mean?
A high 3-Year ROIIC % can signal that a stock is expensive relative to its fundamentals. 3-Year ROIIC % measures the change in earnings as a percentage of change in investment over 3-year. View historical data on argenx SE and its competitors. argenx SE's current 3-Year ROIIC % is 67.34. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is argenx SE stock overvalued right now?
Based on GuruFocus' analysis, argenx SE (ARGX) is currently considered Significantly Undervalued. The stock's GF Value™ is $1,449.85, compared to a current price of $860.94 — trading 40.6% below its estimated fair value. The current 3-Year ROIIC % is 67.34. argenx SE's overall GF Score™ is 78/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is 3-Year ROIIC % calculated?
3-Year ROIIC % is calculated from a company's financial statements. For argenx SE (ARGX), the current 3-Year ROIIC % is 67.34 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is argenx SE (ARGX) Overvalued in 2026?

Based on GuruFocus' analysis, argenx SE stock appears to be undervalued. The current stock price of $860.94 is trading 40.6% below its estimated GF Value™ of $1,449.85. GuruFocus considers argenx SE to be Significantly Undervalued.

Key valuation signals for ARGX:

  • 3-Year ROIIC %: 67.34
  • GF Value™: $1,449.85 vs. price of $860.94 (40.6% below fair value)
  • GF Score™: 78/100 with 5 warning signs

No single metric tells the full story. See the ARGX stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


argenx SE Business Description

Address Laarderhoogtweg 25, Amsterdam, NH, NLD, 1101EB
Argenx is a Dutch biopharmaceutical company focused on developing antibody-based therapies for rare autoimmune diseases. The company's lead product, Vyvgart (efgartigimod), was approved by the FDA in December 2021 for the treatment of generalized myasthenia gravis (gMG). In 2022, Argenx also received FDA approval for Vyvgart Hytrulo, a subcutaneous formulation of Vyvgart, offering a more convenient option compared with Vyvgart's intravenous administration. In 2024, the FDA approved Vyvgart Hytrulo for Chronic Inflammatory Demyelinating Polyneuropathy, a rare immune-mediated neuromuscular disorder of the peripheral nervous system. Argenx is focused on innovation and developing its pipeline for treatments such as primary immune thrombocytopenia, thyroid eye disease, and Sjogren's Disease.
78GF Score

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3-Year ROIIC % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$860.94
Price
$1,449.85
GF Value