ImmuneOnco Biopharmaceuticals (Shanghai) (FRA:R9Z) Debt-to-EBITDA : -1.79 (As of Dec. 2025)

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FRA:R9Z ImmuneOnco Biopharmaceuticals (Shanghai) Inc FRA:R9Z
6 GF Score
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What is ImmuneOnco Biopharmaceuticals (Shanghai) Debt-to-EBITDA?

ImmuneOnco Biopharmaceuticals (Shanghai) FRA:R9Z -2.22% 6 Debt-to-EBITDA is -1.79 as of Dec. 2025. GuruFocus rates FRA:R9Z with a GF Score™ of 6/100. The stock has 5 warning signs investors should review. Among 314 Biotechnology companies, ImmuneOnco Biopharmaceuticals (Shanghai) ranks worse than 318471.02% on this metric.

Debt-to-EBITDA measures a company's ability to pay off its debt.

ImmuneOnco Biopharmaceuticals (Shanghai)'s Short-Term Debt & Capital Lease Obligation for the quarter that ended in Dec. 2025 was €23.68 Mil. ImmuneOnco Biopharmaceuticals (Shanghai)'s Long-Term Debt & Capital Lease Obligation for the quarter that ended in Dec. 2025 was €3.97 Mil. ImmuneOnco Biopharmaceuticals (Shanghai)'s annualized EBITDA for the quarter that ended in Dec. 2025 was €-15.44 Mil. ImmuneOnco Biopharmaceuticals (Shanghai)'s annualized Debt-to-EBITDA for the quarter that ended in Dec. 2025 was -1.79.

A high Debt-to-EBITDA ratio generally means that a company may spend more time to paying off its debt. According to Joel Tillinghast's BIG MONEY THINKS SMALL: Biases, Blind Spots, and Smarter Investing, a ratio of Debt-to-EBITDA exceeding four is usually considered scary unless tangible assets cover the debt.

The historical rank and industry rank for ImmuneOnco Biopharmaceuticals (Shanghai)'s Debt-to-EBITDA or its related term are showing as below:

FRA:R9Z' s Debt-to-EBITDA Range Over the Past 10 Years
Min: -1.14   Med: -0.21   Max: -0.03
Current: -1.07

During the past 5 years, the highest Debt-to-EBITDA Ratio of ImmuneOnco Biopharmaceuticals (Shanghai) was -0.03. The lowest was -1.14. And the median was -0.21.

FRA:R9Z's Debt-to-EBITDA is ranked worse than
100% of 314 companies
in the Biotechnology industry
Industry Median: 1.41 vs FRA:R9Z: -1.07

ImmuneOnco Biopharmaceuticals (Shanghai)  (FRA:R9Z) Debt-to-EBITDA Explanation

In the calculation of Debt-to-EBITDA, we use the total of Short-Term Debt & Capital Lease Obligation and Long-Term Debt & Capital Lease Obligation divided by EBITDA. In some calculations, Total Liabilities is used to for calculation.


Be Aware

A high Debt-to-EBITDA ratio generally means that a company may spend more time to paying off its debt.

According to Joel Tillinghast's BIG MONEY THINKS SMALL: Biases, Blind Spots, and Smarter Investing, a ratio of Debt-to-EBITDA exceeding four is usually considered scary unless tangible assets cover the debt.


ImmuneOnco Biopharmaceuticals (Shanghai) Debt-to-EBITDA Related Terms


ImmuneOnco Biopharmaceuticals (Shanghai) Debt-to-EBITDA Historical Data

* Premium members only.

The historical data trend for ImmuneOnco Biopharmaceuticals (Shanghai)'s Debt-to-EBITDA can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

ImmuneOnco Biopharmaceuticals (Shanghai) Debt-to-EBITDA Chart

ImmuneOnco Biopharmaceuticals (Shanghai) Annual Data
Trend Dec21 Dec22 Dec23 Dec24 Dec25
Debt-to-EBITDA
-0.03 -0.04 -0.21 -0.47 -1.14

ImmuneOnco Biopharmaceuticals (Shanghai) Semi-Annual Data
Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
Debt-to-EBITDA Get a 7-Day Free Trial Premium Member Only -0.18 -0.30 -0.46 -0.51 -1.79

FRA:R9Z vs VRTX, REGN, RVMD: Debt-to-EBITDA Comparison

For the Biotechnology subindustry, ImmuneOnco Biopharmaceuticals (Shanghai)'s Debt-to-EBITDA, along with its competitors' market caps and Debt-to-EBITDA data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


ImmuneOnco Biopharmaceuticals (Shanghai) Debt-to-EBITDA vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, ImmuneOnco Biopharmaceuticals (Shanghai)'s Debt-to-EBITDA distribution charts can be found below:

* The bar in red indicates where ImmuneOnco Biopharmaceuticals (Shanghai)'s Debt-to-EBITDA falls into.


FRA:R9Z
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ImmuneOnco Biopharmaceuticals (Shanghai) Inc FRA:R9Z
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ImmuneOnco Biopharmaceuticals (Shanghai) Debt-to-EBITDA Calculation

Debt-to-EBITDA measures a company's ability to pay off its debt.

ImmuneOnco Biopharmaceuticals (Shanghai)'s Debt-to-EBITDA for the fiscal year that ended in Dec. 2025 is calculated as

Debt-to-EBITDA=Total Debt / EBITDA
=(Short-Term Debt & Capital Lease Obligation + Long-Term Debt & Capital Lease Obligation) / EBITDA
=(23.684 + 3.965) / -24.171
=-1.14

ImmuneOnco Biopharmaceuticals (Shanghai)'s annualized Debt-to-EBITDA for the quarter that ended in Dec. 2025 is calculated as

Debt-to-EBITDA=Total Debt / EBITDA
=(Short-Term Debt & Capital Lease Obligation + Long-Term Debt & Capital Lease Obligation) / EBITDA
=(23.684 + 3.965) / -15.442
=-1.79

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual Debt-to-EBITDA, the EBITDA of the last fiscal year is used. In calculating the annualized quarterly data, the EBITDA data used here is two times the quarterly (Dec. 2025) EBITDA data.

Frequently Asked Questions Learn more about Debt-to-EBITDA →
What does a Debt-to-EBITDA of -1.79 mean?
ImmuneOnco Biopharmaceuticals (Shanghai) (FRA:R9Z) has a Debt-to-EBITDA of -1.79 as of Dec. 2025. Debt-to-EBITDA ratio represents the ratio of total debt to total earnings before interest, taxes, depreciation and amortization. View historical data on ImmuneOnco Biopharmaceuticals (Shanghai). According to the industry distribution chart, ImmuneOnco Biopharmaceuticals (Shanghai) ranks #999999 out of 314 companies in the Biotechnology industry.
Is ImmuneOnco Biopharmaceuticals (Shanghai)'s Debt-to-EBITDA too high?
ImmuneOnco Biopharmaceuticals (Shanghai)'s current Debt-to-EBITDA is -1.79. Based on the distribution chart, ImmuneOnco Biopharmaceuticals (Shanghai) ranks #999999 out of 314 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, ImmuneOnco Biopharmaceuticals (Shanghai) has a GF Score™ of 6/100, reflecting its overall financial health beyond just this single metric.
How does ImmuneOnco Biopharmaceuticals (Shanghai)'s Debt-to-EBITDA compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, ImmuneOnco Biopharmaceuticals (Shanghai) ranks #999999 out of 314 companies for Debt-to-EBITDA. This places ImmuneOnco Biopharmaceuticals (Shanghai) in the lower half of its industry. The industry median Debt-to-EBITDA is 1.41. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Debt-to-EBITDA for a Biotechnology company?
The median Debt-to-EBITDA among Biotechnology companies is 1.41, based on 314 companies in the industry. Companies in the top quartile (top 25%) have a Debt-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, Debt-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Debt-to-EBITDA mean?
A high Debt-to-EBITDA can signal that a stock is expensive relative to its fundamentals. Debt-to-EBITDA ratio represents the ratio of total debt to total earnings before interest, taxes, depreciation and amortization. View historical data on ImmuneOnco Biopharmaceuticals (Shanghai). For the Biotechnology industry, the median Debt-to-EBITDA is 1.41 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. ImmuneOnco Biopharmaceuticals (Shanghai)'s current Debt-to-EBITDA is -1.79. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is ImmuneOnco Biopharmaceuticals (Shanghai) stock overvalued right now?
ImmuneOnco Biopharmaceuticals (Shanghai) (FRA:R9Z) has a current Debt-to-EBITDA of -1.79. The current Debt-to-EBITDA is -1.79. ImmuneOnco Biopharmaceuticals (Shanghai)'s overall GF Score™ is 6/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Debt-to-EBITDA calculated?
Debt-to-EBITDA is calculated from a company's financial statements. For ImmuneOnco Biopharmaceuticals (Shanghai) (FRA:R9Z), the current Debt-to-EBITDA is -1.79 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

ImmuneOnco Biopharmaceuticals (Shanghai) Business Description

Other Exchanges 01541:Hong Kong
Address 1000 Zhangheng Road, Unit 15, China (Shanghai) Pilot Free Trade Zone, Pudong New Area, Shanghai, CHN
ImmuneOnco Biopharmaceuticals (Shanghai) Inc is a science-driven biotechnology company dedicated to the development of immuno-oncology therapies. It is one of the few biotechnology companies globally adopting a systematic approach to harness both the innate and adaptive immune systems. It has designed a robust pipeline of over ten drug candidates with 12 ongoing clinical programs., featured by a comprehensive innate-immunity-based asset portfolio. Its pipeline reflects its extensive understanding of the frontiers of cancer biology and immunology and its expertise in turning scientific research into drug candidates.
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Debt-to-EBITDA is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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