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Otsuka Holdings CoSTU:OS1 +1.71%87 Debt-to-EBITDA is 0.30 as of Mar. 2026, which is 65% below its 10-year median of 0.85. GuruFocus rates STU:OS1 with a GF Score™ of 87/100 and a GF Value™ of €44.72 (Significantly Overvalued). The stock has 5 warning signs investors should review. Among 689 Drug Manufacturers companies, Otsuka Holdings Co ranks better than 77.65% on this metric.
Debt-to-EBITDA measures a company's ability to pay off its debt.
A high Debt-to-EBITDA ratio generally means that a company may spend more time to paying off its debt. According to Joel Tillinghast's BIG MONEY THINKS SMALL: Biases, Blind Spots, and Smarter Investing, a ratio of Debt-to-EBITDA exceeding four is usually considered scary unless tangible assets cover the debt.
The historical rank and industry rank for Otsuka Holdings Co's Debt-to-EBITDA or its related term are showing as below:
STU:OS1'
s Debt-to-EBITDA Range Over the Past 10 Years
Min: 0.31 Med: 0.85 Max: 1.44
Current: 0.31
During the past 13 years, the highest Debt-to-EBITDA Ratio of Otsuka Holdings Co was 1.44. The lowest was 0.31. And the median was 0.85.
STU:OS1's Debt-to-EBITDA is ranked better than 77.65% of 689
companies
in the Drug Manufacturers industry
Industry Median: 1.68
vs STU:OS1: 0.31
Otsuka Holdings Co (STU:OS1) Debt-to-EBITDA Explanation
A high Debt-to-EBITDA ratio generally means that a company may spend more time to paying off its debt.
According to Joel Tillinghast's BIG MONEY THINKS SMALL: Biases, Blind Spots, and Smarter Investing, a ratio of Debt-to-EBITDA exceeding four is usually considered scary unless tangible assets cover the debt.
Otsuka Holdings Co Debt-to-EBITDA Related Terms
Otsuka Holdings Co Debt-to-EBITDA Historical Data
* Premium members only.
The historical data trend for Otsuka Holdings Co's Debt-to-EBITDA can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
STU:OS1 vs LLY, JNJ, ABBV: Debt-to-EBITDA Comparison
For the Drug Manufacturers - General subindustry, Otsuka Holdings Co's Debt-to-EBITDA, along with its competitors' market caps and Debt-to-EBITDA data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Otsuka Holdings Co Debt-to-EBITDA vs Drug Manufacturers Industry
For the Drug Manufacturers industry and Healthcare sector, Otsuka Holdings Co's Debt-to-EBITDA distribution charts can be found below:
* The bar in red indicates where Otsuka Holdings Co's Debt-to-EBITDA falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
In the calculation of annual Debt-to-EBITDA, the EBITDA of the last fiscal year is used. In calculating the annualized quarterly data,
the EBITDA data used here is four times the quarterly (Mar. 2026) EBITDA data.
Otsuka Holdings Co (STU:OS1) has a Debt-to-EBITDA of 0.30 as of Mar. 2026. Debt-to-EBITDA ratio represents the ratio of total debt to total earnings before interest, taxes, depreciation and amortization. View historical data on Otsuka Holdings Co. This is 65% below median its historical median of 0.85. Over the past decade, Otsuka Holdings Co's Debt-to-EBITDA has ranged from 0.31 to 1.44. According to the industry distribution chart, Otsuka Holdings Co ranks #154 out of 689 companies in the Drug Manufacturers industry, placing it in the top 22.4%.
Is Otsuka Holdings Co's Debt-to-EBITDA too high?
Otsuka Holdings Co's current Debt-to-EBITDA of 0.30 is 65% below median its 10-year median of 0.85. Over the past 10 years, this metric has ranged from a low of 0.31 to a high of 1.44. The Drug Manufacturers industry median Debt-to-EBITDA is 1.68. Otsuka Holdings Co's value of 0.30 is 82.1% below this industry median. Based on the distribution chart, Otsuka Holdings Co ranks #154 out of 689 companies in the Drug Manufacturers industry, which is in the top quartile — a strong position relative to peers. Overall, Otsuka Holdings Co has a GF Score™ of 87/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Otsuka Holdings Co's Debt-to-EBITDA compare to LLY and JNJ?
According to the Drug Manufacturers industry distribution chart, Otsuka Holdings Co ranks #154 out of 689 companies for Debt-to-EBITDA. This places Otsuka Holdings Co in the top 22% of its industry — outperforming the majority of peers. The industry median Debt-to-EBITDA is 1.68. Otsuka Holdings Co's value of 0.30 is 82.1% below this benchmark. Historically, Otsuka Holdings Co's own Debt-to-EBITDA has ranged from 0.31 to 1.44 over the past decade. While the company's 10-year median is 0.85 vs. the industry median of 1.68, Otsuka Holdings Co has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Debt-to-EBITDA for a Drug Manufacturers company?
The median Debt-to-EBITDA among Drug Manufacturers companies is 1.68, based on 689 companies in the industry. Companies in the top quartile (top 25%) have a Debt-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, Debt-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Otsuka Holdings Co's current Debt-to-EBITDA of 0.30 is 82.1% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Debt-to-EBITDA mean?
A high Debt-to-EBITDA can signal that a stock is expensive relative to its fundamentals. Debt-to-EBITDA ratio represents the ratio of total debt to total earnings before interest, taxes, depreciation and amortization. View historical data on Otsuka Holdings Co. For the Drug Manufacturers industry, the median Debt-to-EBITDA is 1.68 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Otsuka Holdings Co's current Debt-to-EBITDA is 0.30, which is 65% below median its own 10-year median of 0.85. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Otsuka Holdings Co stock overvalued right now?
Based on GuruFocus' analysis, Otsuka Holdings Co (STU:OS1) is currently considered Significantly Overvalued. The stock's GF Value™ is €44.72, compared to a current price of €59.50 — trading 33.1% above its estimated fair value. The current Debt-to-EBITDA is 0.30, which is 65% below median its 10-year median of 0.85 and 82.1% below the Drug Manufacturers industry median of 1.68. Otsuka Holdings Co's overall GF Score™ is 87/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Debt-to-EBITDA calculated?
Debt-to-EBITDA is calculated from a company's financial statements. For Otsuka Holdings Co (STU:OS1), the current Debt-to-EBITDA is 0.30 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Otsuka Holdings Co (STU:OS1) Overvalued in 2026?
Based on GuruFocus' analysis, Otsuka Holdings Co stock appears to be overvalued.
The current stock price of €59.50 is trading 33.1% above its estimated GF Value™ of €44.72.
GuruFocus considers Otsuka Holdings Co to be Significantly Overvalued.
Key valuation signals for STU:OS1:
Debt-to-EBITDA: 0.30 (65% below median its 10-year median of 0.85)
GF Value™: €44.72 vs. price of €59.50 (33.1% above fair value)
Industry Position: 82.1% below the Drug Manufacturers median (#154 of 689)
No single metric tells the full story. See the STU:OS1 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Otsuka Holdings Co Ltd is a Japan-based company that operates in pharmaceuticals, nutraceuticals, and consumer products. It operates through four reportable segments: Medical-related Business, Nutraceutical-related Business, Consumer-related Business, and Other Business. The Medical Business manufactures and sells therapeutic drugs and infusions, the Nutraceutical Business produces functional foods, beverages, and nutritional supplements, the Consumer Business offers mineral water, beverages, and foods, while the Other Business provides storage services and manufactures chemicals and analytical equipment. It generates the majority of its revenue from the medical-related business segment.
87GF Score
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