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Generate BiomedicinesGENB +1.68%6 Debt-to-Equity is -0.11 as of Dec. 2025. GuruFocus rates GENB with a GF Score™ of 6/100. The stock has 1 warning sign investors should review. Among 970 Biotechnology companies, Generate Biomedicines ranks worse than 103092.68% on this metric.
A high debt to equity ratio generally means that a company has been aggressive in financing its growth with debt. This can result in volatile earnings as a result of the additional interest expense.
The historical rank and industry rank for Generate Biomedicines's Debt-to-Equity or its related term are showing as below:
GENB'
s Debt-to-Equity Range Over the Past 10 Years
Min: -0.18 Med: -0.14 Max: -0.11
Current: -0.11
During the past 2 years, the highest Debt-to-Equity Ratio of Generate Biomedicines was -0.11. The lowest was -0.18. And the median was -0.14.
GENB's Debt-to-Equity is not ranked
in the Biotechnology industry.
Industry Median: 0.16
vs GENB: -0.11
Because a company can increase its ROE % by having more financial leverage, it is important to watch the leverage ratio when investing in high ROE % companies.
Generate Biomedicines Debt-to-Equity Related Terms
Generate Biomedicines Debt-to-Equity Historical Data
* Premium members only.
The historical data trend for Generate Biomedicines's Debt-to-Equity can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Generate Biomedicines Debt-to-Equity Chart
Generate Biomedicines Annual Data
Trend
Dec24
Dec25
Debt-to-Equity
-0.18
-0.11
Generate Biomedicines Semi-Annual Data
Dec24
Dec25
Debt-to-Equity
-0.18
-0.11
GENB vs ZYME, DMRA, SLBT: Debt-to-Equity Comparison
For the Biotechnology subindustry, Generate Biomedicines's Debt-to-Equity, along with its competitors' market caps and Debt-to-Equity data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Generate Biomedicines Debt-to-Equity vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Generate Biomedicines's Debt-to-Equity distribution charts can be found below:
* The bar in red indicates where Generate Biomedicines's Debt-to-Equity falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Generate Biomedicines (GENB) has a Debt-to-Equity of -0.11 as of Dec. 2025. Debt-to-Equity ratio represents the ratio of total debt to total company equity. View historical data on Generate Biomedicines and its competitors. According to the industry distribution chart, Generate Biomedicines ranks #999999 out of 970 companies in the Biotechnology industry.
Is Generate Biomedicines' Debt-to-Equity too high?
Generate Biomedicines' current Debt-to-Equity is -0.11. Based on the distribution chart, Generate Biomedicines ranks #999999 out of 970 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Generate Biomedicines has a GF Score™ of 6/100, reflecting its overall financial health beyond just this single metric.
How does Generate Biomedicines' Debt-to-Equity compare to ZYME and DMRA?
According to the Biotechnology industry distribution chart, Generate Biomedicines ranks #999999 out of 970 companies for Debt-to-Equity. This places Generate Biomedicines in the lower half of its industry. The industry median Debt-to-Equity is 0.16. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Debt-to-Equity for a Biotechnology company?
The median Debt-to-Equity among Biotechnology companies is 0.16, based on 970 companies in the industry. Companies in the top quartile (top 25%) have a Debt-to-Equity significantly above this median, while those in the bottom quartile fall well below. However, Debt-to-Equity should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Debt-to-Equity mean?
A high Debt-to-Equity can signal that a stock is expensive relative to its fundamentals. Debt-to-Equity ratio represents the ratio of total debt to total company equity. View historical data on Generate Biomedicines and its competitors. For the Biotechnology industry, the median Debt-to-Equity is 0.16 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Generate Biomedicines's current Debt-to-Equity is -0.11. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Generate Biomedicines stock overvalued right now?
Generate Biomedicines (GENB) has a current Debt-to-Equity of -0.11. The current Debt-to-Equity is -0.11. Generate Biomedicines' overall GF Score™ is 6/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Debt-to-Equity calculated?
Debt-to-Equity is calculated from a company's financial statements. For Generate Biomedicines (GENB), the current Debt-to-Equity is -0.11 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Generate Biomedicines Inc is a clinical-stage generative biology company pioneering the AI revolution in biotechnology and drug design and development. The company's single operating segment is engaged in the field of generative biology by using machine learning for drug discovery and development through the programming of novel protein therapeutics. Its product candidates include: GB-0895, GB-4362, and GB-5267. Through the company's Generate Platform, it can generate medicines on demand across multiple therapeutic modalities with unprecedented speed representing a fundamental shift in drug discovery.
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