GENB (Generate Biomedicines) Pretax Margin %: -698.59% (As of Dec. 2025)


GENB Generate Biomedicines Inc GENB
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Price $16.92
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What is Generate Biomedicines Pretax Margin %?

Generate Biomedicines GENB +2.18% 6 Pretax Margin % is -698.59% as of Dec. 2025. GuruFocus rates GENB with a GF Score™ of 6/100. The stock has 2 warning signs investors should review. Among 944 Biotechnology companies, Generate Biomedicines ranks worse than 74.68% on this metric.

Pre-Tax margin is calculated as Pre-Tax Income divided by its Revenue. Generate Biomedicines's Pre-Tax Income for the six months ended in Dec. 2025 was $-222.80 Mil. Generate Biomedicines's Revenue for the six months ended in Dec. 2025 was $31.89 Mil. Therefore, Generate Biomedicines's pretax margin for the quarter that ended in Dec. 2025 was -698.59%.

The historical rank and industry rank for Generate Biomedicines's Pretax Margin % or its related term are showing as below:

GENB' s Pretax Margin % Range Over the Past 10 Years
Min: -885.54   Med: -792.07   Max: -698.59
Current: -698.59

GENB's Pretax Margin % is ranked worse than
74.68% of 944 companies
in the Biotechnology industry
Industry Median: -90.5 vs GENB: -698.59

Generate Biomedicines  (NAS:GENB) Pretax Margin % Explanation

The pretax margin, as know as pretax profit margin, is widely used to measure the operating efficiency of a company before deducting taxes.

The pretax margin is sometimes preferred over the net margin as tax expenditures can make profitability comparisons between companies misleading.

It is a useful tool to compare companies operating in the same sector and less effective when comparing companies from other sectors as each industry generally has different operating expenses and sales patterns.

The long term trend of the pretax margin is a good indicator of the competitiveness and health of the business.

Generate Biomedicines Pretax Margin % Related Terms

Generate Biomedicines Pretax Margin % Historical Data

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The historical data trend for Generate Biomedicines's Pretax Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Generate Biomedicines Pretax Margin % Chart

Generate Biomedicines Annual Data
Trend Dec24 Dec25
Pretax Margin %
-885.54 -698.59

Generate Biomedicines Semi-Annual Data
Dec24 Dec25
Pretax Margin % -885.54 -698.59

GENB vs PVLA, SLBT, NKTR: Pretax Margin % Comparison

For the Biotechnology subindustry, Generate Biomedicines's Pretax Margin %, along with its competitors' market caps and Pretax Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.

Generate Biomedicines Pretax Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Generate Biomedicines's Pretax Margin % distribution charts can be found below:

* The bar in red indicates where Generate Biomedicines's Pretax Margin % falls into.


GENB
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Generate Biomedicines Inc GENB
Pretax Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Generate Biomedicines Pretax Margin % Calculation

Pretax margin - also known as pretax profit margin is the ratio of Pretax Income divided by net sales or Revenue, usually presented in percent.

Generate Biomedicines's Pretax Margin for the fiscal year that ended in Dec. 2025 is calculated as

Pretax Margin=Pre-Tax Income (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=-222.802/31.893
=-698.59 %

Generate Biomedicines's Pretax Margin for the quarter that ended in Dec. 2025 is calculated as

Pretax Margin=Pre-Tax Income (Q: Dec. 2025 )/Revenue (Q: Dec. 2025 )
=-222.802/31.893
=-698.59 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Pretax Margin % →
What does a Pretax Margin % of -698.59% mean?
Generate Biomedicines (GENB) has a Pretax Margin % of -698.59% as of Dec. 2025. Pre-Tax margin is the ratio of total pre-tax income to net sales. View historical data on Generate Biomedicines and its competitors. According to the industry distribution chart, Generate Biomedicines ranks #705 out of 944 companies in the Biotechnology industry, placing it in the top 74.7%.
Is Generate Biomedicines' Pretax Margin % too high?
Generate Biomedicines' current Pretax Margin % is -698.59%. Based on the distribution chart, Generate Biomedicines ranks #705 out of 944 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Generate Biomedicines has a GF Score™ of 6/100, reflecting its overall financial health beyond just this single metric.
How does Generate Biomedicines' Pretax Margin % compare to PVLA and SLBT?
According to the Biotechnology industry distribution chart, Generate Biomedicines ranks #705 out of 944 companies for Pretax Margin %. This places Generate Biomedicines in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Pretax Margin % for a Biotechnology company?
A good Pretax Margin % depends on the Biotechnology industry context. However, Pretax Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Pretax Margin % mean?
A high Pretax Margin % can signal that a stock is expensive relative to its fundamentals. Pre-Tax margin is the ratio of total pre-tax income to net sales. View historical data on Generate Biomedicines and its competitors. Generate Biomedicines's current Pretax Margin % is -698.59%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Generate Biomedicines stock overvalued right now?
Generate Biomedicines (GENB) has a current Pretax Margin % of -698.59%. The current Pretax Margin % is -698.59%. Generate Biomedicines' overall GF Score™ is 6/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Pretax Margin % calculated?
Pretax Margin % is calculated from a company's financial statements. For Generate Biomedicines (GENB), the current Pretax Margin % is -698.59% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Generate Biomedicines Business Description

Address 101 South Street, Suite 900, Somerville, MA, USA, 02143
Generate Biomedicines Inc is a clinical-stage generative biology company pioneering the AI revolution in biotechnology and drug design and development. The company's single operating segment is engaged in the field of generative biology by using machine learning for drug discovery and development through the programming of novel protein therapeutics. Its product candidates include: GB-0895, GB-4362, and GB-5267. Through the company's Generate Platform, it can generate medicines on demand across multiple therapeutic modalities with unprecedented speed representing a fundamental shift in drug discovery.
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