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Nautilus BiotechnologyNAUT +3.38%22 Debt-to-Equity is 0.21 as of Jun. 2026, which is 62% above its 10-year median of 0.13. GuruFocus rates NAUT with a GF Score™ of 22/100. The stock has 3 warning signs investors should review. Among 968 Biotechnology companies, Nautilus Biotechnology ranks worse than 55.89% on this metric.
A high debt to equity ratio generally means that a company has been aggressive in financing its growth with debt. This can result in volatile earnings as a result of the additional interest expense.
The historical rank and industry rank for Nautilus Biotechnology's Debt-to-Equity or its related term are showing as below:
NAUT'
s Debt-to-Equity Range Over the Past 10 Years
Min: -0.16 Med: 0.13 Max: 0.21
Current: 0.21
During the past 6 years, the highest Debt-to-Equity Ratio of Nautilus Biotechnology was 0.21. The lowest was -0.16. And the median was 0.13.
NAUT's Debt-to-Equity is ranked worse than 55.89% of 968
companies
in the Biotechnology industry
Industry Median: 0.16
vs NAUT: 0.21
Because a company can increase its ROE % by having more financial leverage, it is important to watch the leverage ratio when investing in high ROE % companies.
Nautilus Biotechnology Debt-to-Equity Related Terms
Nautilus Biotechnology Debt-to-Equity Historical Data
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The historical data trend for Nautilus Biotechnology's Debt-to-Equity can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
NAUT vs SLNCF, CHRS, AVXL: Debt-to-Equity Comparison
For the Biotechnology subindustry, Nautilus Biotechnology's Debt-to-Equity, along with its competitors' market caps and Debt-to-Equity data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Nautilus Biotechnology Debt-to-Equity vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Nautilus Biotechnology's Debt-to-Equity distribution charts can be found below:
* The bar in red indicates where Nautilus Biotechnology's Debt-to-Equity falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Nautilus Biotechnology (NAUT) has a Debt-to-Equity of 0.21 as of Jun. 2026. Debt-to-Equity ratio represents the ratio of total debt to total company equity. View historical data on Nautilus Biotechnology and its competitors. This is 62% above median its historical median of 0.13. According to the industry distribution chart, Nautilus Biotechnology ranks #541 out of 968 companies in the Biotechnology industry, placing it in the top 55.9%.
Is Nautilus Biotechnology's Debt-to-Equity too high?
Nautilus Biotechnology's current Debt-to-Equity of 0.21 is 62% above median its 10-year median of 0.13. The Biotechnology industry median Debt-to-Equity is 0.16. Nautilus Biotechnology's value of 0.21 is 31.3% above this industry median. Based on the distribution chart, Nautilus Biotechnology ranks #541 out of 968 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Nautilus Biotechnology has a GF Score™ of 22/100, reflecting its overall financial health beyond just this single metric.
How does Nautilus Biotechnology's Debt-to-Equity compare to SLNCF and CHRS?
According to the Biotechnology industry distribution chart, Nautilus Biotechnology ranks #541 out of 968 companies for Debt-to-Equity. This places Nautilus Biotechnology in the lower half of its industry. The industry median Debt-to-Equity is 0.16. Nautilus Biotechnology's value of 0.21 is 31.3% above this benchmark. While the company's 10-year median is 0.13 vs. the industry median of 0.16, Nautilus Biotechnology has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Debt-to-Equity for a Biotechnology company?
The median Debt-to-Equity among Biotechnology companies is 0.16, based on 968 companies in the industry. Companies in the top quartile (top 25%) have a Debt-to-Equity significantly above this median, while those in the bottom quartile fall well below. However, Debt-to-Equity should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Nautilus Biotechnology's current Debt-to-Equity of 0.21 is 31.3% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Debt-to-Equity mean?
A high Debt-to-Equity can signal that a stock is expensive relative to its fundamentals. Debt-to-Equity ratio represents the ratio of total debt to total company equity. View historical data on Nautilus Biotechnology and its competitors. For the Biotechnology industry, the median Debt-to-Equity is 0.16 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Nautilus Biotechnology's current Debt-to-Equity is 0.21, which is 62% above median its own 10-year median of 0.13. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Nautilus Biotechnology stock overvalued right now?
Nautilus Biotechnology (NAUT) has a current Debt-to-Equity of 0.21. The current Debt-to-Equity is 0.21, which is 62% above median its 10-year median of 0.13 and 31.3% above the Biotechnology industry median of 0.16. Nautilus Biotechnology's overall GF Score™ is 22/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Debt-to-Equity calculated?
Debt-to-Equity is calculated from a company's financial statements. For Nautilus Biotechnology (NAUT), the current Debt-to-Equity is 0.21 as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Nautilus Biotechnology Inc is a development stage life sciences company creating a platform technology for quantifying and unlocking the complexity of the human proteome. The Company transform the field of proteomics by democratizing access to the proteome and enabling fundamental advancements across human health and medicine. Its products includes: Proteome Analysis System, Reagent Kits, Software and analysis.
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