NAUT (Nautilus Biotechnology) Moat Score: 4/10 (As of Jun. 29, 2026)


NAUT Nautilus Biotechnology Inc NAUT
28 GF Score
Price $1.79
! 2 Warning Signs
View Full Analysis

What is Nautilus Biotechnology Moat Score?

Nautilus Biotechnology NAUT -13.11% 28 Moat Score is 4 as of Jun. 29, 2026. GuruFocus rates NAUT with a GF Score™ of 28/100. The stock has 2 warning signs investors should review. Among 1,401 Biotechnology companies, Nautilus Biotechnology ranks better than 88.79% on this metric.

Nautilus Biotechnology has the Moat Score of 4, which implies that the company might have Narrow Moat - Discernible but modest moat.

Nautilus Biotechnology has Narrow Moat: Nautilus Biotechnology has a discernible moat due to its innovative R&D capabilities and proprietary technology in proteomics. However, it is still developing its market presence and lacks strong customer switching costs or network effects.

Moat Score is a ranking system developed by GuruFocus to assess a company's ability to sustain a competitive advantage, rated on a scale from 0 to 10. It takes into account key factors such as market leadership, cost advantages, network effects, customer switching costs, and more.

The company's Moat Score is based on these criteria:

1. Market leadership and sustainable market share
2. Network effects and significant customer switching costs
3. Valuable intellectual property and patents
4. Strong brand strength and deep customer loyalty
5. Durable cost advantages (e.g., economies of scale, proprietary technology)
6. Significant regulatory barriers and exclusive licenses
7. Superior distribution network
8. Strong and sustainable pricing power
9. Consistent and impactful innovation and R&D capabilities

Based on the research, GuruFocus believes Nautilus Biotechnology might have Narrow Moat - Discernible but modest moat.

Nautilus Biotechnology  (NAS:NAUT) Moat Score Explanation

The Moat Score ranges from 0 to 10, with 10 as the highest. GuruFocus divided Moat Score into following 8 categories:

Moat Score Moat Level
10Wide Moat - Exceptionally dominant and durable wide moat
8 - 9Wide Moat - Clear and robust wide moat
7Wide Moat - Entry-level wide moat, clearly possessing durable advantages
6Narrow Moat - Strong narrow moat, clearly distinguishable but not wide
5Narrow Moat - Solid narrow moat
4Narrow Moat - Discernible but modest moat
1 - 3No Moat - Very weak/transient advantages
0No Moat - No discernible moat

Nautilus Biotechnology Moat Score Related Terms

NAUT vs IVVD, ACIU, OTLK: Moat Score Comparison

For the Biotechnology subindustry, Nautilus Biotechnology's Moat Score, along with its competitors' market caps and Moat Score data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.

Nautilus Biotechnology Moat Score vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Nautilus Biotechnology's Moat Score distribution charts can be found below:

* The bar in red indicates where Nautilus Biotechnology's Moat Score falls into.


NAUT
28GF Score
Nautilus Biotechnology Inc NAUT
Moat Score is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis
Frequently Asked Questions Learn more about Moat Score →
What does a Moat Score of 4 mean?
Nautilus Biotechnology (NAUT) has a Moat Score of 4 as of Jun. 29, 2026. Moat Score is a ranking system developed by GuruFocus to assess a company's ability to sustain a competitive advantage, rated on a scale from 0 to 10. It takes into account key factors such as market leadership, cost advantages, network effects, customer switching costs, and more. According to the industry distribution chart, Nautilus Biotechnology ranks #157 out of 1401 companies in the Biotechnology industry, placing it in the top 11.2%.
Is Nautilus Biotechnology's Moat Score too high?
Nautilus Biotechnology's current Moat Score is 4. The Biotechnology industry median Moat Score is 2.00. Nautilus Biotechnology's value of 4 is 100% above this industry median. Based on the distribution chart, Nautilus Biotechnology ranks #157 out of 1401 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Nautilus Biotechnology has a GF Score™ of 28/100, reflecting its overall financial health beyond just this single metric.
How does Nautilus Biotechnology's Moat Score compare to IVVD and ACIU?
According to the Biotechnology industry distribution chart, Nautilus Biotechnology ranks #157 out of 1401 companies for Moat Score. This places Nautilus Biotechnology in the top 11% of its industry — outperforming the majority of peers. The industry median Moat Score is 2.00. Nautilus Biotechnology's value of 4 is 100% above this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Moat Score for a Biotechnology company?
The median Moat Score among Biotechnology companies is 2.00, based on 1,401 companies in the industry. Companies in the top quartile (top 25%) have a Moat Score significantly above this median, while those in the bottom quartile fall well below. However, Moat Score should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Nautilus Biotechnology's current Moat Score of 4 is 100% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Moat Score mean?
A high Moat Score can signal that a stock is expensive relative to its fundamentals. Moat Score is a ranking system developed by GuruFocus to assess a company's ability to sustain a competitive advantage, rated on a scale from 0 to 10. It takes into account key factors such as market leadership, cost advantages, network effects, customer switching costs, and more. For the Biotechnology industry, the median Moat Score is 2.00 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Nautilus Biotechnology's current Moat Score is 4. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Nautilus Biotechnology stock overvalued right now?
Nautilus Biotechnology (NAUT) has a current Moat Score of 4. The current Moat Score is 4 and 100% above the Biotechnology industry median of 2.00. Nautilus Biotechnology's overall GF Score™ is 28/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Moat Score calculated?
Moat Score is calculated from a company's financial statements. For Nautilus Biotechnology (NAUT), the current Moat Score is 4 as of Jun. 29, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Nautilus Biotechnology Business Description

Address 2701 Eastlake Avenue East, Seattle, WA, USA, 98102
Nautilus Biotechnology Inc is a development stage life sciences company creating a platform technology for quantifying and unlocking the complexity of the human proteome. The Company transform the field of proteomics by democratizing access to the proteome and enabling fundamental advancements across human health and medicine. Its products includes: Proteome Analysis System, Reagent Kits, Software and analysis.
28GF Score

Get the complete analysis for NAUT

Moat Score is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$1.79
Price