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hVIVOOPORF +27.29%48 Degree of Operating Leverage is 4.89 as of Dec. 2025. GuruFocus rates OPORF with a GF Score™ of 48/100 and a GF Value™ of $0.27. The stock has 6 warning signs investors should review. Among 197 Medical Diagnostics & Research companies, hVIVO ranks worse than 81.22% on this metric.
Degree of Operating Leverage (DOL) measures the percentage change in EBIT for a unit change in Revenue.
hVIVO's Degree of Operating Leverage for the quarter that ended in Dec. 2025 was 4.89. The higher Degree of Operating Leverage, the higher operating risk the company will take.
The industry rank for hVIVO's Degree of Operating Leverage or its related term are showing as below:
OPORF's Degree of Operating Leverage is ranked worse than 81.22% of 197
companies
in the Medical Diagnostics & Research industry
Industry Median: 0.44
vs OPORF: 4.89
hVIVO (OTCPK:OPORF) Degree of Operating Leverage Explanation
Degree of Operating Leverage (DOL) is a leverage ratio that measures the sensitivity of a company’s operting income, also referred to as Earnings Before Interest and Taxes (EBIT), to fluctuations in its Revenue. DOL is a method used to quantify a company’s operating risk. This risk is related to the company's structure of variable costs and fixed costs. Since the fixed costs do not allow the company to adjust the operating costs, the operating risk rises with a higher fixed-to-variable costs proportion.
A high Degree of Operating Leverage indicates that the company’s fixed costs exceed its variable costs. By increasing the sales, the company can earn more profits. In addition, the company must be able to maintain relatively high sales to cover all fixed costs.
Be Aware
The use of operating leverage varies across different industries and business sectors, and the application of Degree of Operating Leverage (DOL) should be adjusted accordingly.
hVIVO Degree of Operating Leverage Related Terms
hVIVO Degree of Operating Leverage Historical Data
* Premium members only.
The historical data trend for hVIVO's Degree of Operating Leverage can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
OPORF vs TMO, DHR, NTRA: Degree of Operating Leverage Comparison
For the Diagnostics & Research subindustry, hVIVO's Degree of Operating Leverage, along with its competitors' market caps and Degree of Operating Leverage data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
hVIVO Degree of Operating Leverage vs Medical Diagnostics & Research Industry
For the Medical Diagnostics & Research industry and Healthcare sector, hVIVO's Degree of Operating Leverage distribution charts can be found below:
* The bar in red indicates where hVIVO's Degree of Operating Leverage falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
** TTM data of EBIT and Revenue was used to calculate Degree of Operating Leverage.
*** Please be aware that the Degree of Operating Leverage calculations are based on company-level data using the primary share class. The calculated data provided is for demonstration purposes and may slightly differ from the results displayed in the title due to potential variations caused by currency exchange rate differences throughout the year.
What does a Degree of Operating Leverage of 4.89 mean?
hVIVO (OPORF) has a Degree of Operating Leverage of 4.89 as of Dec. 2025. Degree of Operating Leverage (DOL) measures the percentage change in EBIT for a unit change in Revenue. View historical data for hVIVO and its competitors. According to the industry distribution chart, hVIVO ranks #160 out of 197 companies in the Medical Diagnostics & Research industry, placing it in the top 81.2%.
Is hVIVO's Degree of Operating Leverage too high?
hVIVO's current Degree of Operating Leverage is 4.89. The Medical Diagnostics & Research industry median Degree of Operating Leverage is 0.44. hVIVO's value of 4.89 is 1011.4% above this industry median. Based on the distribution chart, hVIVO ranks #160 out of 197 companies in the Medical Diagnostics & Research industry, which is in the bottom quartile relative to peers. Overall, hVIVO has a GF Score™ of 48/100, reflecting its overall financial health beyond just this single metric.
How does hVIVO's Degree of Operating Leverage compare to TMO and DHR?
According to the Medical Diagnostics & Research industry distribution chart, hVIVO ranks #160 out of 197 companies for Degree of Operating Leverage. This places hVIVO in the lower half of its industry. The industry median Degree of Operating Leverage is 0.44. hVIVO's value of 4.89 is 1011.4% above this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Degree of Operating Leverage for a Medical Diagnostics & Research company?
The median Degree of Operating Leverage among Medical Diagnostics & Research companies is 0.44, based on 197 companies in the industry. Companies in the top quartile (top 25%) have a Degree of Operating Leverage significantly above this median, while those in the bottom quartile fall well below. However, Degree of Operating Leverage should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. hVIVO's current Degree of Operating Leverage of 4.89 is 1011.4% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Degree of Operating Leverage mean?
A high Degree of Operating Leverage can signal that a stock is expensive relative to its fundamentals. Degree of Operating Leverage (DOL) measures the percentage change in EBIT for a unit change in Revenue. View historical data for hVIVO and its competitors. For the Medical Diagnostics & Research industry, the median Degree of Operating Leverage is 0.44 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. hVIVO's current Degree of Operating Leverage is 4.89. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is hVIVO stock overvalued right now?
hVIVO (OPORF) has a current Degree of Operating Leverage of 4.89. The stock's GF Value™ is $0.27, compared to a current price of $0.11 — trading 59.4% below its estimated fair value. The current Degree of Operating Leverage is 4.89 and 1011.4% above the Medical Diagnostics & Research industry median of 0.44. hVIVO's overall GF Score™ is 48/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Degree of Operating Leverage calculated?
Degree of Operating Leverage is calculated from a company's financial statements. For hVIVO (OPORF), the current Degree of Operating Leverage is 4.89 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is hVIVO (OPORF) Overvalued in 2026?
Based on GuruFocus' analysis, hVIVO stock appears to be undervalued.
The current stock price of $0.11 is trading 59.4% below its estimated GF Value™ of $0.27.
Key valuation signals for OPORF:
Degree of Operating Leverage: 4.89
GF Value™: $0.27 vs. price of $0.11 (59.4% below fair value)
Industry Position: 1011.4% above the Medical Diagnostics & Research median (#160 of 197)
No single metric tells the full story. See the OPORF stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
hVIVO PLC is a full-service early phase Contract Research Organisation (CRO). It delivers end-to-end clinical development services to a diverse and expanding client base. The group specialises in conducting human challenge trials across multiple infectious and respiratory indications. It also offers comprehensive virology and immunology laboratory services under the hLAB brand. Through its subsidiary, it provides early-phase clinical trial services and Early Drug Development Consulting and Biometry services to the biopharma sector. It provides development solutions from preclinical stages through Phase II trials, via FluCamp. Geographically, the company generates maximum revenue from Europe, followed by North America, the United Kingdom, and Asia.
48GF Score
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