hVIVO (OPORF) Return-on-Tangible-Equity: -51.88% (As of Dec. 2025)


OPORF hVIVO PLC OPORF
42 GF Score
Price $0.11
GF Value $0.25
Valuation Possible Value Trap
! 6 Warning Signs
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What is hVIVO Return-on-Tangible-Equity?

hVIVO OPORF +27.29% 42 Return-on-Tangible-Equity is -51.88% as of Dec. 2025. GuruFocus rates OPORF with a GF Score™ of 42/100 and a GF Value™ of $0.25 (Possible Value Trap). The stock has 6 warning signs investors should review. Among 193 Medical Diagnostics & Research companies, hVIVO ranks worse than 66.32% on this metric.

Return-on-Tangible-Equity is calculated as Net Income divided by its average total shareholder tangible equity. Total shareholder tangible equity equals to Total Stockholders Equity minus Intangible Assets. hVIVO's annualized net income for the quarter that ended in Dec. 2025 was $-15.75 Mil. hVIVO's average shareholder tangible equity for the quarter that ended in Dec. 2025 was $30.36 Mil. Therefore, hVIVO's annualized Return-on-Tangible-Equity for the quarter that ended in Dec. 2025 was -51.88%.

The historical rank and industry rank for hVIVO's Return-on-Tangible-Equity or its related term are showing as below:

OPORF' s Return-on-Tangible-Equity Range Over the Past 10 Years
Min: -361.92   Med: -5.42   Max: 75.21
Current: -21.41

During the past 13 years, hVIVO's highest Return-on-Tangible-Equity was 75.21%. The lowest was -361.92%. And the median was -5.42%.

OPORF's Return-on-Tangible-Equity is ranked worse than
66.32% of 193 companies
in the Medical Diagnostics & Research industry
Industry Median: 0.07 vs OPORF: -21.41

hVIVO  (OTCPK:OPORF) Return-on-Tangible-Equity Explanation

Return-on-Tangible-Equity measures the rate of return on the ownership interest (shareholder's tangible equity) of the common stock owners. It measures a firm's efficiency at generating profits from every unit of shareholders' tangible equity (shareholders equity minus intangibles). Return-on-Tangible-Equity shows how well a company uses investment funds to generate earnings growth. Return-on-Tangible-Equitys between 15% and 20% are considered desirable.


Be Aware

Net Income is used.

Because a company can increase its Return-on-Tangible-Equity by having more financial leverage, it is important to watch the leverage ratio when investing in high Return-on-Tangible-Equity companies. Like Return-on-Tangible-Asset, Return-on-Tangible-Equity is calculated with only 12 months data. Fluctuations in company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.

Asset light businesses require very few assets to generate very high earnings. Their Return-on-Tangible-Equitys can be extremely high.


hVIVO Return-on-Tangible-Equity Related Terms


hVIVO Return-on-Tangible-Equity Historical Data

* Premium members only.

The historical data trend for hVIVO's Return-on-Tangible-Equity can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

hVIVO Return-on-Tangible-Equity Chart

hVIVO Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Return-on-Tangible-Equity
Get a 7-Day Free Trial Premium Member Only Premium Member Only -0.48 -5.18 76.16 31.48 -21.36

hVIVO Semi-Annual Data
Jun16 Dec16 Jun17 Dec17 Jun18 Dec18 Jun19 Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
Return-on-Tangible-Equity Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 110.05 34.32 29.99 -0.71 -51.88

OPORF vs TMO, DHR, IDXX: Return-on-Tangible-Equity Comparison

For the Diagnostics & Research subindustry, hVIVO's Return-on-Tangible-Equity, along with its competitors' market caps and Return-on-Tangible-Equity data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


hVIVO Return-on-Tangible-Equity vs Medical Diagnostics & Research Industry

For the Medical Diagnostics & Research industry and Healthcare sector, hVIVO's Return-on-Tangible-Equity distribution charts can be found below:

* The bar in red indicates where hVIVO's Return-on-Tangible-Equity falls into.


OPORF
42GF Score
hVIVO PLC OPORF
Return-on-Tangible-Equity is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

hVIVO Return-on-Tangible-Equity Calculation

hVIVO's annualized Return-on-Tangible-Equity for the fiscal year that ended in Dec. 2025 is calculated as

Return-on-Tangible-Equity=Net Income/( (Total Tangible Equity+Total Tangible Equity)/ count )
(A: Dec. 2025 )  (A: Dec. 2024 )(A: Dec. 2025 )
=Net Income/( (Total Stockholders Equity - Intangible Assets+Total Stockholders Equity - Intangible Assets )/ count )
(A: Dec. 2025 )  (A: Dec. 2024 )(A: Dec. 2025 )
=-8.023/( (49.272+25.833 )/ 2 )
=-8.023/37.5525
=-21.36 %

hVIVO's annualized Return-on-Tangible-Equity for the quarter that ended in Dec. 2025 is calculated as

Return-on-Tangible-Equity=Net Income/( (Total Tangible Equity+Total Tangible Equity)/ count )
(Q: Dec. 2025 )  (Q: Jun. 2025 )(Q: Dec. 2025 )
=Net Income/( (Total Stockholders Equity - Intangible Assets+Total Stockholders Equity - Intangible Assets)/ count )
(Q: Dec. 2025 )  (Q: Jun. 2025 )(Q: Dec. 2025 )
=-15.752/( (34.893+25.833)/ 2 )
=-15.752/30.363
=-51.88 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual Return-on-Tangible-Equity, the net income of the last fiscal year and the average total shareholder tangible equity over the fiscal year are used. In calculating the quarterly data, the net income data used here is two times the semi-annual (Dec. 2025) net income data. Return-on-Tangible-Equity is displayed in the 10-year financial page.

What does a Return-on-Tangible-Equity of -51.88% mean?
hVIVO (OPORF) has a Return-on-Tangible-Equity of -51.88% as of Dec. 2025. Return on tangible equity is the ratio of current-period net income to average two-period tangible equity. View historical data on hVIVO and its competitors. According to the industry distribution chart, hVIVO ranks #128 out of 193 companies in the Medical Diagnostics & Research industry, placing it in the top 66.3%.
Is hVIVO's Return-on-Tangible-Equity too high?
hVIVO's current Return-on-Tangible-Equity is -51.88%. Based on the distribution chart, hVIVO ranks #128 out of 193 companies in the Medical Diagnostics & Research industry, which is below the industry midpoint. Overall, hVIVO has a GF Score™ of 42/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does hVIVO's Return-on-Tangible-Equity compare to TMO and DHR?
According to the Medical Diagnostics & Research industry distribution chart, hVIVO ranks #128 out of 193 companies for Return-on-Tangible-Equity. This places hVIVO in the lower half of its industry. The industry median Return-on-Tangible-Equity is 0.07. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Return-on-Tangible-Equity for a Medical Diagnostics & Research company?
The median Return-on-Tangible-Equity among Medical Diagnostics & Research companies is 0.07, based on 193 companies in the industry. Companies in the top quartile (top 25%) have a Return-on-Tangible-Equity significantly above this median, while those in the bottom quartile fall well below. However, Return-on-Tangible-Equity should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Return-on-Tangible-Equity mean?
A high Return-on-Tangible-Equity can signal that a stock is expensive relative to its fundamentals. Return on tangible equity is the ratio of current-period net income to average two-period tangible equity. View historical data on hVIVO and its competitors. For the Medical Diagnostics & Research industry, the median Return-on-Tangible-Equity is 0.07 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. hVIVO's current Return-on-Tangible-Equity is -51.88%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is hVIVO stock overvalued right now?
Based on GuruFocus' analysis, hVIVO (OPORF) is currently considered Possible Value Trap. The stock's GF Value™ is $0.25, compared to a current price of $0.11 — trading 56.2% below its estimated fair value. The current Return-on-Tangible-Equity is -51.88%. hVIVO's overall GF Score™ is 42/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Return-on-Tangible-Equity calculated?
Return-on-Tangible-Equity is calculated from a company's financial statements. For hVIVO (OPORF), the current Return-on-Tangible-Equity is -51.88% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is hVIVO (OPORF) Overvalued in 2026?

Based on GuruFocus' analysis, hVIVO stock appears to be undervalued. The current stock price of $0.11 is trading 56.2% below its estimated GF Value™ of $0.25. GuruFocus considers hVIVO to be Possible Value Trap.

Key valuation signals for OPORF:

  • Return-on-Tangible-Equity: -51.88%
  • GF Value™: $0.25 vs. price of $0.11 (56.2% below fair value)
  • GF Score™: 42/100 with 6 warning signs

No single metric tells the full story. See the OPORF stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


hVIVO Business Description

Other Exchanges HVO:UKCRO:Germany
Address 40 Bank Street, Floor 24, London, GBR, E14 5NR
hVIVO PLC is a full-service early phase Contract Research Organisation (CRO). It delivers end-to-end clinical development services to a diverse and expanding client base. The group specialises in conducting human challenge trials across multiple infectious and respiratory indications. It also offers comprehensive virology and immunology laboratory services under the hLAB brand. Through its subsidiary, it provides early-phase clinical trial services and Early Drug Development Consulting and Biometry services to the biopharma sector. It provides development solutions from preclinical stages through Phase II trials, via FluCamp. Geographically, the company generates maximum revenue from Europe, followed by North America, the United Kingdom, and Asia.
42GF Score

Get the complete analysis for OPORF

Return-on-Tangible-Equity is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$0.11
Price
$0.25
GF Value