PLX (Protalix BioTherapeutics) Degree of Operating Leverage : 5.61 (As of Jun. 2026)

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PLX Protalix BioTherapeutics Inc PLX
54 GF Score
Price $2.34
GF Value $2.20
Valuation Fairly Valued
! 4 Warning Signs
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What is Protalix BioTherapeutics Degree of Operating Leverage?

Protalix BioTherapeutics PLX +2.18% 54 Degree of Operating Leverage is 5.61 as of Jun. 2026. GuruFocus rates PLX with a GF Score™ of 54/100 and a GF Value™ of $2.20 (Fairly Valued). The stock has 4 warning signs investors should review. Among 850 Biotechnology companies, Protalix BioTherapeutics ranks worse than 87.76% on this metric.

Degree of Operating Leverage (DOL) measures the percentage change in EBIT for a unit change in Revenue. Protalix BioTherapeutics's Degree of Operating Leverage for the quarter that ended in Jun. 2026 was 5.61. The higher Degree of Operating Leverage, the higher operating risk the company will take.

The industry rank for Protalix BioTherapeutics's Degree of Operating Leverage or its related term are showing as below:

PLX's Degree of Operating Leverage is ranked worse than
87.76% of 850 companies
in the Biotechnology industry
Industry Median: -0.02 vs PLX: 5.61

Protalix BioTherapeutics  (AMEX:PLX) Degree of Operating Leverage Explanation

Degree of Operating Leverage (DOL) is a leverage ratio that measures the sensitivity of a company’s operting income, also referred to as Earnings Before Interest and Taxes (EBIT), to fluctuations in its Revenue. DOL is a method used to quantify a company’s operating risk. This risk is related to the company's structure of variable costs and fixed costs. Since the fixed costs do not allow the company to adjust the operating costs, the operating risk rises with a higher fixed-to-variable costs proportion.

A high Degree of Operating Leverage indicates that the company’s fixed costs exceed its variable costs. By increasing the sales, the company can earn more profits. In addition, the company must be able to maintain relatively high sales to cover all fixed costs.

Be Aware

The use of operating leverage varies across different industries and business sectors, and the application of Degree of Operating Leverage (DOL) should be adjusted accordingly.


Protalix BioTherapeutics Degree of Operating Leverage Related Terms


Protalix BioTherapeutics Degree of Operating Leverage Historical Data

* Premium members only.

The historical data trend for Protalix BioTherapeutics's Degree of Operating Leverage can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Protalix BioTherapeutics Degree of Operating Leverage Chart

Protalix BioTherapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Degree of Operating Leverage
Get a 7-Day Free Trial Premium Member Only Premium Member Only 18.76 -1.67 -5.31 3.01 148.05

Protalix BioTherapeutics Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Degree of Operating Leverage Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -2.70 -5.54 148.05 9.23 5.61

PLX vs GLSI, DTIL, NERV: Degree of Operating Leverage Comparison

For the Biotechnology subindustry, Protalix BioTherapeutics's Degree of Operating Leverage, along with its competitors' market caps and Degree of Operating Leverage data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Protalix BioTherapeutics Degree of Operating Leverage vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Protalix BioTherapeutics's Degree of Operating Leverage distribution charts can be found below:

* The bar in red indicates where Protalix BioTherapeutics's Degree of Operating Leverage falls into.


PLX
54GF Score
Protalix BioTherapeutics Inc PLX
Degree of Operating Leverage is just one metric. See GF Score™, valuation, warning signs, and more.
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Protalix BioTherapeutics Degree of Operating Leverage Calculation

Protalix BioTherapeutics's Degree of Operating Leverage for the quarter that ended in Jun. 2026 is calculated as:

Degree of Operating Leverage=% Change in EBIT**/% Change in Revenue
=( 24.714 (Jun. 2026) / 9.182 (Jun. 2025) - 1 )/( 80.619 (Jun. 2026) / 61.948 (Jun. 2025) - 1 )
=1.6916/0.3014
=5.61***

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

** TTM data of EBIT and Revenue was used to calculate Degree of Operating Leverage.
*** Please be aware that the Degree of Operating Leverage calculations are based on company-level data using the primary share class. The calculated data provided is for demonstration purposes and may slightly differ from the results displayed in the title due to potential variations caused by currency exchange rate differences throughout the year.

What does a Degree of Operating Leverage of 5.61 mean?
Protalix BioTherapeutics (PLX) has a Degree of Operating Leverage of 5.61 as of Jun. 2026. Degree of Operating Leverage (DOL) measures the percentage change in EBIT for a unit change in Revenue. View historical data for Protalix BioTherapeutics and its competitors. According to the industry distribution chart, Protalix BioTherapeutics ranks #746 out of 850 companies in the Biotechnology industry, placing it in the top 87.8%.
Is Protalix BioTherapeutics' Degree of Operating Leverage too high?
Protalix BioTherapeutics' current Degree of Operating Leverage is 5.61. Based on the distribution chart, Protalix BioTherapeutics ranks #746 out of 850 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Protalix BioTherapeutics has a GF Score™ of 54/100 and is considered Fairly Valued, reflecting its overall financial health beyond just this single metric.
How does Protalix BioTherapeutics' Degree of Operating Leverage compare to GLSI and DTIL?
According to the Biotechnology industry distribution chart, Protalix BioTherapeutics ranks #746 out of 850 companies for Degree of Operating Leverage. This places Protalix BioTherapeutics in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Degree of Operating Leverage for a Biotechnology company?
A good Degree of Operating Leverage depends on the Biotechnology industry context. However, Degree of Operating Leverage should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Degree of Operating Leverage mean?
A high Degree of Operating Leverage can signal that a stock is expensive relative to its fundamentals. Degree of Operating Leverage (DOL) measures the percentage change in EBIT for a unit change in Revenue. View historical data for Protalix BioTherapeutics and its competitors. Protalix BioTherapeutics's current Degree of Operating Leverage is 5.61. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Protalix BioTherapeutics stock overvalued right now?
Based on GuruFocus' analysis, Protalix BioTherapeutics (PLX) is currently considered Fairly Valued. The stock's GF Value™ is $2.20, compared to a current price of $2.34 — trading 6.4% above its estimated fair value. The current Degree of Operating Leverage is 5.61. Protalix BioTherapeutics' overall GF Score™ is 54/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Degree of Operating Leverage calculated?
Degree of Operating Leverage is calculated from a company's financial statements. For Protalix BioTherapeutics (PLX), the current Degree of Operating Leverage is 5.61 as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Protalix BioTherapeutics (PLX) Overvalued in 2026?

Based on GuruFocus' analysis, Protalix BioTherapeutics stock appears to be overvalued. The current stock price of $2.34 is trading 6.4% above its estimated GF Value™ of $2.20. GuruFocus considers Protalix BioTherapeutics to be Fairly Valued.

Key valuation signals for PLX:

  • Degree of Operating Leverage: 5.61
  • GF Value™: $2.20 vs. price of $2.34 (6.4% above fair value)
  • GF Score™: 54/100 with 4 warning signs

No single metric tells the full story. See the PLX stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Protalix BioTherapeutics Business Description

Other Exchanges PBDA:Germany
Address 2 University Plaza, Suite 100, Hackensack, NJ, USA, 07601
Protalix BioTherapeutics Inc is a commercial-stage biopharmaceutical company focused on the discovery, development, production, and commercialization of therapeutics for rare diseases with important unmet needs. ProCellEx, a proprietary plant cell-based protein expression system, represents a new method for developing recombinant proteins in an industrial-scale manner. corporate includes the development of treatments for rare and orphan diseases. The Company operates as a single operating segment in Israel.
54GF Score

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Degree of Operating Leverage is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$2.34
Price
$2.20
GF Value