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EV-to-EBITDA is calculated as enterprise value divided by its EBITDA. As of today, Protalix BioTherapeutics's enterprise value is $157.09 Mil.
Protalix BioTherapeutics's EBITDA for the trailing twelve months (TTM) ended in Jun. 2026 was $26.28 Mil. Therefore, Protalix BioTherapeutics's EV-to-EBITDA for today is 5.98.
The historical rank and industry rank for Protalix BioTherapeutics's EV-to-EBITDA or its related term are showing as below:
PLX'
s EV-to-EBITDA Range Over the Past 10 Years
Min: -79.31 Med: -2.73 Max: 64.34
Current: 5.98
During the past 13 years, the highest EV-to-EBITDA of Protalix BioTherapeutics was 64.34. The lowest was -79.31. And the median was -2.73.
PLX's EV-to-EBITDA is ranked better than 66.58% of 401
companies
in the Biotechnology industry
Industry Median: 13.6
vs PLX: 5.98
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio to determine the fair market value of a company.
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
Protalix BioTherapeutics's PE Ratio (TTM) for today is calculated as:
Protalix BioTherapeutics's share price for today is $2.34.
Protalix BioTherapeutics's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $0.230.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Study has found that the companies with the lowest EV-to-EBITDA outperforms companies measured as cheap by other ratios such as PE Ratio (TTM).
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Biotechnology subindustry, Protalix BioTherapeutics's EV-to-EBITDA, along with its competitors' market caps and EV-to-EBITDA data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Protalix BioTherapeutics EV-to-EBITDA vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Protalix BioTherapeutics's EV-to-EBITDA distribution charts can be found below:
* The bar in red indicates where Protalix BioTherapeutics's EV-to-EBITDA falls into.
Protalix BioTherapeutics's current Enterprise Value is $157.09 Mil.
Protalix BioTherapeutics's EBITDA for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $26.28 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Protalix BioTherapeutics (PLX) has a EV-to-EBITDA of 5.98 as of Aug. 19, 2026. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Protalix BioTherapeutics. According to the industry distribution chart, Protalix BioTherapeutics ranks #134 out of 401 companies in the Biotechnology industry, placing it in the top 33.4%.
Is Protalix BioTherapeutics' EV-to-EBITDA too high?
Protalix BioTherapeutics' current EV-to-EBITDA is 5.98. The Biotechnology industry median EV-to-EBITDA is 13.60. Protalix BioTherapeutics' value of 5.98 is 56% below this industry median. Based on the distribution chart, Protalix BioTherapeutics ranks #134 out of 401 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Protalix BioTherapeutics has a GF Score™ of 54/100 and is considered Fairly Valued, reflecting its overall financial health beyond just this single metric.
How does Protalix BioTherapeutics' EV-to-EBITDA compare to GLSI and DTIL?
According to the Biotechnology industry distribution chart, Protalix BioTherapeutics ranks #134 out of 401 companies for EV-to-EBITDA. This puts Protalix BioTherapeutics in the upper half of its industry. The industry median EV-to-EBITDA is 13.60. Protalix BioTherapeutics' value of 5.98 is 56% below this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBITDA for a Biotechnology company?
The median EV-to-EBITDA among Biotechnology companies is 13.60, based on 401 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Protalix BioTherapeutics's current EV-to-EBITDA of 5.98 is 56% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBITDA mean?
A high EV-to-EBITDA can signal that a stock is expensive relative to its fundamentals. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Protalix BioTherapeutics. For the Biotechnology industry, the median EV-to-EBITDA is 13.60 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Protalix BioTherapeutics's current EV-to-EBITDA is 5.98. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Protalix BioTherapeutics stock overvalued right now?
Based on GuruFocus' analysis, Protalix BioTherapeutics (PLX) is currently considered Fairly Valued. The stock's GF Value™ is $2.21, compared to a current price of $2.34 — trading 5.9% above its estimated fair value. The current EV-to-EBITDA is 5.98 and 56% below the Biotechnology industry median of 13.60. Protalix BioTherapeutics' overall GF Score™ is 54/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBITDA calculated?
EV-to-EBITDA is calculated from a company's financial statements. For Protalix BioTherapeutics (PLX), the current EV-to-EBITDA is 5.98 as of Aug. 19, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Protalix BioTherapeutics (PLX) Overvalued in 2026?
Based on GuruFocus' analysis, Protalix BioTherapeutics stock appears to be overvalued.
The current stock price of $2.34 is trading 5.9% above its estimated GF Value™ of $2.21.
GuruFocus considers Protalix BioTherapeutics to be Fairly Valued.
Key valuation signals for PLX:
EV-to-EBITDA: 5.98
GF Value™: $2.21 vs. price of $2.34 (5.9% above fair value)
Industry Position: 56% below the Biotechnology median (#134 of 401)
No single metric tells the full story. See the PLX stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Protalix BioTherapeutics Inc is a commercial-stage biopharmaceutical company focused on the discovery, development, production, and commercialization of therapeutics for rare diseases with important unmet needs. ProCellEx, a proprietary plant cell-based protein expression system, represents a new method for developing recombinant proteins in an industrial-scale manner. corporate includes the development of treatments for rare and orphan diseases. The Company operates as a single operating segment in Israel.
54GF Score
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