AKBA (Akebia Therapeutics) E10: $-2.03 (As of Mar. 2026)


AKBA Akebia Therapeutics Inc AKBA
49 GF Score
Price $1.14
GF Value $1.31
Valuation Modestly Undervalued
! 4 Warning Signs
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What is Akebia Therapeutics E10?

Akebia Therapeutics AKBA +10.14% 49 E10 is $-2.03 as of Mar. 2026. GuruFocus rates AKBA with a GF Score™ of 49/100 and a GF Value™ of $1.31 (Modestly Undervalued). The stock has 4 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years.

Akebia Therapeutics's adjusted earnings per share data for the three months ended in Mar. 2026 was $-0.030. Add all the adjusted EPS for the past 10 years together and divide 10 will get our e10, which is $-2.03 for the trailing ten years ended in Mar. 2026.

During the past 3 years, the average E10 Growth Rate was 37.10% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the E10 growth rate using E10 data.

During the past 13 years, the highest 3-Year average E10 Growth Rate of Akebia Therapeutics was 37.10% per year. The lowest was 37.10% per year. And the median was 37.10% per year.

As of today (2026-06-28), Akebia Therapeutics's current stock price is $1.14. Akebia Therapeutics's E10 for the quarter that ended in Mar. 2026 was $-2.03. Akebia Therapeutics's Shiller PE Ratio of today is .


Akebia Therapeutics  (NAS:AKBA) E10 Explanation

If a company grows much fast than inflation, E10 may underestimate the company's earnings power. Shiller PE Ratio can seem to be too high even the actual P/E is low.

For the Shiller P/E, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller P/E is also called PE10.

The Shiller P/E was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.


Be Aware

Shiller PE Ratio works better for cyclical companies. It gives you a better idea on the company's real earnings power.


Akebia Therapeutics E10 Related Terms


Akebia Therapeutics E10 Historical Data

* Premium members only.

The historical data trend for Akebia Therapeutics's E10 can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Akebia Therapeutics E10 Chart

Akebia Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
E10
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 -8.40 -7.87 -2.24 -2.09

Akebia Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
E10 Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -2.19 0.00 0.00 -2.09 -2.03

AKBA vs TKNO, ORGO, SIGA: E10 Comparison

For the Drug Manufacturers - Specialty & Generic subindustry, Akebia Therapeutics's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Akebia Therapeutics Shiller PE Ratio vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Akebia Therapeutics's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where Akebia Therapeutics's Shiller PE Ratio falls into.


AKBA
49GF Score
Akebia Therapeutics Inc AKBA
E10 is just one metric. See GF Score™, valuation, warning signs, and more.
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Akebia Therapeutics E10 Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. When we calculate the today's Shiller P/E ratio of a stock, we use today's price divided by E10.

What is E10? How do we calculate E10?

E10 is the average of the inflation adjusted earnings of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the E10 of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the earnings from 2001 through 2010.

We adjusted the earnings of 2001 earnings data with the total inflation from 2001 through 2010 to the equivalent earnings in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart earned $1 a share in 2001, then the 2001's equivalent earnings in 2010 is $1.4 a share. If Wal-Mart earns $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 earnings in 2010 is $1.35. So on and so forth, you get the equivalent earnings of past 10 years. Then you add them together and divided the sum by 10 to get E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, Akebia Therapeutics's adjusted earnings per share data for the three months ended in Mar. 2026 was:

Adj_EPS= Earnings per Share (Diluted) /CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=-0.03/330.2130*330.2130
=-0.030

Current CPI (Mar. 2026) = 330.2130.

Akebia Therapeutics Quarterly Data

per share eps CPI Adj_EPS
201606 -0.950 241.018 -1.302
201609 -0.960 241.428 -1.313
201612 -0.990 241.432 -1.354
201703 -1.150 243.801 -1.558
201706 -0.530 244.955 -0.714
201709 -0.490 246.819 -0.656
201712 0.420 246.524 0.563
201803 -0.480 249.554 -0.635
201806 -0.600 251.989 -0.786
201809 -0.460 252.439 -0.602
201812 -0.756 251.233 -0.994
201903 -0.620 254.202 -0.805
201906 -0.490 256.143 -0.632
201909 -0.460 256.759 -0.592
201912 -0.790 256.974 -1.015
202003 -0.470 258.115 -0.601
202006 -1.280 257.797 -1.640
202009 -0.420 260.280 -0.533
202012 -0.600 260.474 -0.761
202103 -0.450 264.877 -0.561
202106 -0.510 271.696 -0.620
202109 -0.340 274.310 -0.409
202112 -0.400 278.802 -0.474
202203 -0.350 287.504 -0.402
202206 0.150 296.311 0.167
202209 -0.290 296.808 -0.323
202212 -0.040 296.797 -0.045
202303 -0.150 301.836 -0.164
202306 -0.060 305.109 -0.065
202309 -0.080 307.789 -0.086
202312 0.003 306.746 0.003
202403 -0.090 312.332 -0.095
202406 -0.040 314.175 -0.042
202409 -0.100 315.301 -0.105
202412 -0.100 315.605 -0.105
202503 0.030 319.799 0.031
202506 0.000 322.561 0.000
202509 0.000 324.800 0.000
202512 -0.050 324.054 -0.051
202603 -0.030 330.213 -0.030

Add all the adjusted EPS together and divide 10 will get our e10.

Frequently Asked Questions Learn more about E10 →
What does a E10 of $-2.03 mean?
Akebia Therapeutics (AKBA) has a E10 of $-2.03 as of Mar. 2026. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Akebia Therapeutics and its competitors.
Is Akebia Therapeutics' E10 too high?
Akebia Therapeutics' current E10 is $-2.03. Overall, Akebia Therapeutics has a GF Score™ of 49/100 and is considered Modestly Undervalued, reflecting its overall financial health beyond just this single metric.
How does Akebia Therapeutics' E10 compare to TKNO and ORGO?
Akebia Therapeutics' E10 of $-2.03 can be compared against companies in the Drug Manufacturers industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good E10 for a Drug Manufacturers company?
A good E10 depends on the Drug Manufacturers industry context. However, E10 should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high E10 mean?
A high E10 can signal that a stock is expensive relative to its fundamentals. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Akebia Therapeutics and its competitors. Akebia Therapeutics's current E10 is $-2.03. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Akebia Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Akebia Therapeutics (AKBA) is currently considered Modestly Undervalued. The stock's GF Value™ is $1.31, compared to a current price of $1.14 — trading 13% below its estimated fair value. The current E10 is $-2.03. Akebia Therapeutics' overall GF Score™ is 49/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is E10 calculated?
E10 is calculated from a company's financial statements. For Akebia Therapeutics (AKBA), the current E10 is $-2.03 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Akebia Therapeutics (AKBA) Overvalued in 2026?

Based on GuruFocus' analysis, Akebia Therapeutics stock appears to be undervalued. The current stock price of $1.14 is trading 13% below its estimated GF Value™ of $1.31. GuruFocus considers Akebia Therapeutics to be Modestly Undervalued.

Key valuation signals for AKBA:

  • E10: $-2.03
  • GF Value™: $1.31 vs. price of $1.14 (13% below fair value)
  • GF Score™: 49/100 with 4 warning signs

No single metric tells the full story. See the AKBA stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Akebia Therapeutics Business Description

Other Exchanges AX9:Germany
Address 245 First Street, Suite 1400, Cambridge, MA, USA, 02142
Akebia Therapeutics Inc is a fully integrated biopharmaceutical company. The Company's operating segment is the business of developing and commercializing novel therapeutics. The current portfolio of the company includes Auryxia (ferric citrate), a medicine approved and marketed in the United States for the control of serum phosphorus levels in adult patients with dialysis-dependent chronic kidney disease and the treatment of iron deficiency anemia, in adult patients with non-dialysis-dependent chronic kidney disease, Vafseo (vadadustat), an oral hypoxia-inducible factor prolyl hydroxylase, inhibitor approved in Japan for the treatment of anemia due to chronic kidney disease, and HIF-PH inhibitors in preclinical development.
49GF Score

Get the complete analysis for AKBA

E10 is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$1.14
Price
$1.31
GF Value