INVA (Innoviva) E10: $2.48 (As of Mar. 2026)


INVA Innoviva Inc INVA
89 GF Score
Price $23.58
GF Value $20.37
Valuation Modestly Overvalued
! 5 Warning Signs
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What is Innoviva E10?

Innoviva INVA +0.99% 89 E10 is $2.48 as of Mar. 2026. GuruFocus rates INVA with a GF Score™ of 89/100 and a GF Value™ of $20.37 (Modestly Overvalued). The stock has 5 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years.

Innoviva's adjusted earnings per share data for the three months ended in Mar. 2026 was $2.220. Add all the adjusted EPS for the past 10 years together and divide 10 will get our e10, which is $2.48 for the trailing ten years ended in Mar. 2026.

During the past 12 months, Innoviva's average E10 Growth Rate was 37.00% per year. During the past 3 years, the average E10 Growth Rate was 26.00% per year. During the past 5 years, the average E10 Growth Rate was 41.60% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the E10 growth rate using E10 data.

During the past 13 years, the highest 3-Year average E10 Growth Rate of Innoviva was 66.90% per year. The lowest was 15.70% per year. And the median was 28.60% per year.

As of today (2026-06-27), Innoviva's current stock price is $23.58. Innoviva's E10 for the quarter that ended in Mar. 2026 was $2.48. Innoviva's Shiller PE Ratio of today is 9.51.

During the past 13 years, the highest Shiller PE Ratio of Innoviva was 144.60. The lowest was 8.41. And the median was 10.95.


Innoviva  (NAS:INVA) E10 Explanation

If a company grows much fast than inflation, E10 may underestimate the company's earnings power. Shiller PE Ratio can seem to be too high even the actual P/E is low.

For the Shiller P/E, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller P/E is also called PE10.

The Shiller P/E was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.

Innoviva's Shiller P/E Ratio of today is calculated as

Shiller PE Ratio=Share Price/E10
=23.58/2.48
=9.51

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

During the past 13 years, the highest Shiller P/E Ratio of Innoviva was 144.60. The lowest was 8.41. And the median was 10.95.


Be Aware

Shiller PE Ratio works better for cyclical companies. It gives you a better idea on the company's real earnings power.


Innoviva E10 Related Terms


Innoviva E10 Historical Data

* Premium members only.

The historical data trend for Innoviva's E10 can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Innoviva E10 Chart

Innoviva Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
E10
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.82 1.11 1.58 1.85 2.22

Innoviva Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
E10 Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 1.81 1.91 2.04 2.22 2.48

INVA vs IMTX, VIR, PGEN: E10 Comparison

For the Biotechnology subindustry, Innoviva's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Innoviva Shiller PE Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Innoviva's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where Innoviva's Shiller PE Ratio falls into.


INVA
89GF Score
Innoviva Inc INVA
E10 is just one metric. See GF Score™, valuation, warning signs, and more.
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Innoviva E10 Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. When we calculate the today's Shiller P/E ratio of a stock, we use today's price divided by E10.

What is E10? How do we calculate E10?

E10 is the average of the inflation adjusted earnings of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the E10 of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the earnings from 2001 through 2010.

We adjusted the earnings of 2001 earnings data with the total inflation from 2001 through 2010 to the equivalent earnings in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart earned $1 a share in 2001, then the 2001's equivalent earnings in 2010 is $1.4 a share. If Wal-Mart earns $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 earnings in 2010 is $1.35. So on and so forth, you get the equivalent earnings of past 10 years. Then you add them together and divided the sum by 10 to get E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, Innoviva's adjusted earnings per share data for the three months ended in Mar. 2026 was:

Adj_EPS= Earnings per Share (Diluted) /CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=2.22/330.2130*330.2130
=2.220

Current CPI (Mar. 2026) = 330.2130.

Innoviva Quarterly Data

per share eps CPI Adj_EPS
201606 0.130 241.018 0.178
201609 0.130 241.428 0.178
201612 0.220 241.432 0.301
201703 0.150 243.801 0.203
201706 0.300 244.955 0.404
201709 0.210 246.819 0.281
201712 0.500 246.524 0.670
201803 0.270 249.554 0.357
201806 0.490 251.989 0.642
201809 0.430 252.439 0.562
201812 2.340 251.233 3.076
201903 0.310 254.202 0.403
201906 0.340 256.143 0.438
201909 0.360 256.759 0.463
201912 0.420 256.974 0.540
202003 0.590 258.115 0.755
202006 0.690 257.797 0.884
202009 0.260 260.280 0.330
202012 0.480 260.474 0.609
202103 0.840 264.877 1.047
202106 0.900 271.696 1.094
202109 0.900 274.310 1.083
202112 0.140 278.802 0.166
202203 0.200 287.504 0.230
202206 0.010 296.311 0.011
202209 2.800 296.808 3.115
202212 -0.980 296.797 -1.090
202303 0.420 301.836 0.459
202306 0.020 305.109 0.022
202309 0.980 307.789 1.051
202312 0.760 306.746 0.818
202403 0.460 312.332 0.486
202406 -0.550 314.175 -0.578
202409 0.020 315.301 0.021
202412 0.260 315.605 0.272
202503 -0.740 319.799 -0.764
202506 0.770 322.561 0.788
202509 1.080 324.800 1.098
202512 1.940 324.054 1.977
202603 2.220 330.213 2.220

Add all the adjusted EPS together and divide 10 will get our e10.

Frequently Asked Questions Learn more about E10 →
What does a E10 of $2.48 mean?
Innoviva (INVA) has a E10 of $2.48 as of Mar. 2026. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Innoviva and its competitors.
Is Innoviva's E10 too high?
Innoviva's current E10 is $2.48. Overall, Innoviva has a GF Score™ of 89/100 and is considered Modestly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Innoviva's E10 compare to IMTX and VIR?
Innoviva's E10 of $2.48 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good E10 for a Biotechnology company?
A good E10 depends on the Biotechnology industry context. However, E10 should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high E10 mean?
A high E10 can signal that a stock is expensive relative to its fundamentals. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Innoviva and its competitors. Innoviva's current E10 is $2.48. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Innoviva stock overvalued right now?
Based on GuruFocus' analysis, Innoviva (INVA) is currently considered Modestly Overvalued. The stock's GF Value™ is $20.37, compared to a current price of $23.58 — trading 15.8% above its estimated fair value. The current E10 is $2.48. Innoviva's overall GF Score™ is 89/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is E10 calculated?
E10 is calculated from a company's financial statements. For Innoviva (INVA), the current E10 is $2.48 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Innoviva (INVA) Overvalued in 2026?

Based on GuruFocus' analysis, Innoviva stock appears to be overvalued. The current stock price of $23.58 is trading 15.8% above its estimated GF Value™ of $20.37. GuruFocus considers Innoviva to be Modestly Overvalued.

Key valuation signals for INVA:

  • E10: $2.48
  • GF Value™: $20.37 vs. price of $23.58 (15.8% above fair value)
  • GF Score™: 89/100 with 5 warning signs

No single metric tells the full story. See the INVA stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Innoviva Business Description

Other Exchanges HVE:Germany
Address 1350 Old Bayshore Highway, Suite 400, Burlingame, CA, USA, 94010
Innoviva Inc is a company with a portfolio of royalty healthcare assets. It has three primary sets of assets: a royalty portfolio, operating assets in critical care and infectious disease, and other strategic healthcare assets. Its product offering includes Relvar/Breo/Ellipta, Anoro, Trelegy, and others.
89GF Score

Get the complete analysis for INVA

E10 is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$23.58
Price
$20.37
GF Value