MGNX (Macrogenics) E10: $-2.57 (As of Jun. 2026)

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MGNX Macrogenics Inc MGNX
51 GF Score
Price $4.10
GF Value $3.98
Valuation Fairly Valued
! 6 Warning Signs
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What is Macrogenics E10?

Macrogenics MGNX +1.11% 51 E10 is $-2.57 as of Jun. 2026. GuruFocus rates MGNX with a GF Score™ of 51/100 and a GF Value™ of $3.98 (Fairly Valued). The stock has 6 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years.

Macrogenics's adjusted earnings per share data for the three months ended in Jun. 2026 was $0.310. Add all the adjusted EPS for the past 10 years together and divide 10 will get our e10, which is $-2.57 for the trailing ten years ended in Jun. 2026.

During the past 3 years, the average E10 Growth Rate was -2.40% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the E10 growth rate using E10 data.

During the past 13 years, the highest 3-Year average E10 Growth Rate of Macrogenics was -2.40% per year. The lowest was -2.40% per year. And the median was -2.40% per year.

As of today (2026-08-24), Macrogenics's current stock price is $4.10. Macrogenics's E10 for the quarter that ended in Jun. 2026 was $-2.57. Macrogenics's Shiller PE Ratio of today is .


Macrogenics  (NAS:MGNX) E10 Explanation

If a company grows much fast than inflation, E10 may underestimate the company's earnings power. Shiller PE Ratio can seem to be too high even the actual P/E is low.

For the Shiller P/E, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller P/E is also called PE10.

The Shiller P/E was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.


Be Aware

Shiller PE Ratio works better for cyclical companies. It gives you a better idea on the company's real earnings power.


Macrogenics E10 Related Terms


Macrogenics E10 Historical Data

* Premium members only.

The historical data trend for Macrogenics's E10 can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Macrogenics E10 Chart

Macrogenics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
E10
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 -2.26 -2.35 -2.34 -2.43

Macrogenics Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
E10 Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -2.61 -2.54 -2.43 -2.41 -2.57

MGNX vs RNAC, CNXU, GALT: E10 Comparison

For the Biotechnology subindustry, Macrogenics's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Macrogenics Shiller PE Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Macrogenics's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where Macrogenics's Shiller PE Ratio falls into.


MGNX
51GF Score
Macrogenics Inc MGNX
E10 is just one metric. See GF Score™, valuation, warning signs, and more.
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Macrogenics E10 Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. When we calculate the today's Shiller P/E ratio of a stock, we use today's price divided by E10.

What is E10? How do we calculate E10?

E10 is the average of the inflation adjusted earnings of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the E10 of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the earnings from 2001 through 2010.

We adjusted the earnings of 2001 earnings data with the total inflation from 2001 through 2010 to the equivalent earnings in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart earned $1 a share in 2001, then the 2001's equivalent earnings in 2010 is $1.4 a share. If Wal-Mart earns $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 earnings in 2010 is $1.35. So on and so forth, you get the equivalent earnings of past 10 years. Then you add them together and divided the sum by 10 to get E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, Macrogenics's adjusted earnings per share data for the three months ended in Jun. 2026 was:

Adj_EPS= Earnings per Share (Diluted) /CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=0.31/333.9520*333.9520
=0.310

Current CPI (Jun. 2026) = 333.9520.

Macrogenics Quarterly Data

per share eps CPI Adj_EPS
201609 -0.970 241.428 -1.342
201612 -1.000 241.432 -1.383
201703 -1.080 243.801 -1.479
201706 -1.140 244.955 -1.554
201709 -1.280 246.819 -1.732
201712 2.960 246.524 4.010
201803 -1.340 249.554 -1.793
201806 -1.030 251.989 -1.365
201809 -0.810 252.439 -1.072
201812 -1.060 251.233 -1.409
201903 -0.990 254.202 -1.301
201906 -0.650 256.143 -0.847
201909 -0.910 256.759 -1.184
201912 -0.620 256.974 -0.806
202003 -0.910 258.115 -1.177
202006 -0.940 257.797 -1.218
202009 -0.660 260.280 -0.847
202012 0.020 260.474 0.026
202103 -0.900 264.877 -1.135
202106 -0.660 271.696 -0.811
202109 -0.860 274.310 -1.047
202112 -0.950 278.802 -1.138
202203 -1.080 287.504 -1.254
202206 -0.670 296.311 -0.755
202209 -0.400 296.808 -0.450
202212 0.210 296.797 0.236
202303 -0.610 301.836 -0.675
202306 0.920 305.109 1.007
202309 0.280 307.789 0.304
202312 -0.750 306.746 -0.817
202403 -0.840 312.332 -0.898
202406 -0.890 314.175 -0.946
202409 0.900 315.301 0.953
202412 -0.250 315.605 -0.265
202503 -0.650 319.799 -0.679
202506 -0.570 322.561 -0.590
202509 0.270 324.800 0.278
202512 -0.220 324.054 -0.227
202603 -0.580 330.213 -0.587
202606 0.310 333.952 0.310

Add all the adjusted EPS together and divide 10 will get our e10.

Frequently Asked Questions Learn more about E10 →
What does a E10 of $-2.57 mean?
Macrogenics (MGNX) has a E10 of $-2.57 as of Jun. 2026. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Macrogenics and its competitors.
Is Macrogenics' E10 too high?
Macrogenics' current E10 is $-2.57. Overall, Macrogenics has a GF Score™ of 51/100 and is considered Fairly Valued, reflecting its overall financial health beyond just this single metric.
How does Macrogenics' E10 compare to RNAC and CNXU?
Macrogenics' E10 of $-2.57 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good E10 for a Biotechnology company?
A good E10 depends on the Biotechnology industry context. However, E10 should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high E10 mean?
A high E10 can signal that a stock is expensive relative to its fundamentals. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Macrogenics and its competitors. Macrogenics's current E10 is $-2.57. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Macrogenics stock overvalued right now?
Based on GuruFocus' analysis, Macrogenics (MGNX) is currently considered Fairly Valued. The stock's GF Value™ is $3.98, compared to a current price of $4.10 — trading 3% above its estimated fair value. The current E10 is $-2.57. Macrogenics' overall GF Score™ is 51/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is E10 calculated?
E10 is calculated from a company's financial statements. For Macrogenics (MGNX), the current E10 is $-2.57 as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Macrogenics (MGNX) Overvalued in 2026?

Based on GuruFocus' analysis, Macrogenics stock appears to be overvalued. The current stock price of $4.10 is trading 3% above its estimated GF Value™ of $3.98. GuruFocus considers Macrogenics to be Fairly Valued.

Key valuation signals for MGNX:

  • E10: $-2.57
  • GF Value™: $3.98 vs. price of $4.10 (3% above fair value)
  • GF Score™: 51/100 with 6 warning signs

No single metric tells the full story. See the MGNX stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Macrogenics Business Description

Other Exchanges M55:Germany
Address 9704 Medical Center Drive, Rockville, MD, USA, 20850
Macrogenics Inc is a clinical-stage biopharmaceutical company focused on developing antibody-based therapeutics for the treatment of cancer. The company is currently developing therapeutics utilizing multiple modalities, including antibody-drug conjugates (ADCs) and multi-specific antibodies (which it refers to as DART and TRIDENT molecules). It is advancing three proprietary product candidates in clinical development: lorigerlimab, a bispecific DART molecule that targets checkpoint inhibitors PD-1 and CTLA-4; MGC026, an ADC that targets B7-H3 and delivers a novel topoisomerase I inhibitor (TOP1i)-based linker-payload, and MGC028, an ADC that targets ADAM9 and delivers a novel TOP1i-based linker-payload. Its segment is developing and commercializing monoclonal antibody-based therapeutics.
51GF Score

Get the complete analysis for MGNX

E10 is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$4.10
Price
$3.98
GF Value