MacrogenicsMGNX -2.90%47 Net Margin % is -177.01% as of Mar. 2026. GuruFocus rates MGNX with a GF Score™ of 47/100 and a GF Value™ of $4.06 (Modestly Overvalued). The stock has 8 warning signs investors should review. Among 938 Biotechnology companies, Macrogenics ranks better than 56.29% on this metric.
Net margin is calculated as Net Income divided by its Revenue. Macrogenics's Net Income for the
three
months ended in Mar. 2026 was $-36.8 Mil. Macrogenics's Revenue for the
three
months ended in Mar. 2026 was $20.8 Mil. Therefore, Macrogenics's net margin for the quarter that ended in Mar. 2026 was -177.01%.
The historical rank and industry rank for Macrogenics's Net Margin % or its related term are showing as below:
MGNX'
s Net Margin % Range Over the Past 10 Years
Min: -292.36 Med: -73.72 Max: -12.62
Current: -44.79
MGNX's Net Margin % is ranked better than 56.29% of 938
companies
in the Biotechnology industry
Industry Median: -88.09
vs MGNX: -44.79
Macrogenics (NAS:MGNX) Net Margin % Explanation
Although Net Income and Earnings-per-Share (EPS) are the most widely used parameter in measuring a company's profitability and valuation, it is the least reliable. The reason is that reported earnings can be manipulated easily by adjusting any numbers such as Depreciation, Depletion and Amotorization and non-recurring items.
But the long term trend of the net margin is a good indicator of the competitiveness and health of the business.
Macrogenics Net Margin % Related Terms
Macrogenics Net Margin % Historical Data
* Premium members only.
The historical data trend for Macrogenics's Net Margin % can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
MGNX vs IMRX, TRDA, SLNCF: Net Margin % Comparison
For the Biotechnology subindustry, Macrogenics's Net Margin %, along with its competitors' market caps and Net Margin % data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Macrogenics Net Margin % vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Macrogenics's Net Margin % distribution charts can be found below:
* The bar in red indicates where Macrogenics's Net Margin % falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Macrogenics (MGNX) has a Net Margin % of -177.01% as of Mar. 2026. Net margin is the ratio of total net income to net sales. View historical data on Macrogenics and its competitors. According to the industry distribution chart, Macrogenics ranks #410 out of 938 companies in the Biotechnology industry, placing it in the top 43.7%.
Is Macrogenics' Net Margin % too high?
Macrogenics' current Net Margin % is -177.01%. Based on the distribution chart, Macrogenics ranks #410 out of 938 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Macrogenics has a GF Score™ of 47/100 and is considered Modestly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Macrogenics' Net Margin % compare to IMRX and TRDA?
According to the Biotechnology industry distribution chart, Macrogenics ranks #410 out of 938 companies for Net Margin %. This puts Macrogenics in the upper half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Net Margin % for a Biotechnology company?
A good Net Margin % depends on the Biotechnology industry context. However, Net Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Net Margin % mean?
A high Net Margin % can signal that a stock is expensive relative to its fundamentals. Net margin is the ratio of total net income to net sales. View historical data on Macrogenics and its competitors. Macrogenics's current Net Margin % is -177.01%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Macrogenics stock overvalued right now?
Based on GuruFocus' analysis, Macrogenics (MGNX) is currently considered Modestly Overvalued. The stock's GF Value™ is $4.06, compared to a current price of $4.53 — trading 11.5% above its estimated fair value. The current Net Margin % is -177.01%. Macrogenics' overall GF Score™ is 47/100 with 8 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Net Margin % calculated?
Net Margin % is calculated from a company's financial statements. For Macrogenics (MGNX), the current Net Margin % is -177.01% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Macrogenics (MGNX) Overvalued in 2026?
Based on GuruFocus' analysis, Macrogenics stock appears to be overvalued.
The current stock price of $4.53 is trading 11.5% above its estimated GF Value™ of $4.06.
GuruFocus considers Macrogenics to be Modestly Overvalued.
Key valuation signals for MGNX:
Net Margin %: -177.01%
GF Value™: $4.06 vs. price of $4.53 (11.5% above fair value)
No single metric tells the full story. See the MGNX stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Macrogenics Inc is a clinical-stage biopharmaceutical company focused on developing antibody-based therapeutics for the treatment of cancer. The company is currently developing therapeutics utilizing multiple modalities, including antibody-drug conjugates (ADCs) and multi-specific antibodies (which it refers to as DART and TRIDENT molecules). It is advancing three proprietary product candidates in clinical development: lorigerlimab, a bispecific DART molecule that targets checkpoint inhibitors PD-1 and CTLA-4; MGC026, an ADC that targets B7-H3 and delivers a novel topoisomerase I inhibitor (TOP1i)-based linker-payload, and MGC028, an ADC that targets ADAM9 and delivers a novel TOP1i-based linker-payload. Its segment is developing and commercializing monoclonal antibody-based therapeutics.
47GF Score
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